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Triton X-100

Product Name
Triton X-100
CAS No.
9002-93-1
Chemical Name
Triton X-100
Synonyms
Triton X 100;X-405;tritonx;OCTOXYNOL-40;OCTYLPHENYLPOLYETHYLENE GLYCOL;NP 40;Octoxinol;tx100;TERGITOL NP-9;NONIDET P 40
CBNumber
CB6682291
Molecular Formula
(C2H4O)nC14H22O
Formula Weight
324.41192
MOL File
9002-93-1.mol
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Triton X-100 Property

Melting point:
44-46 °C
Boiling point:
250 °C(lit.)
Density 
1.06 g/mL at 20 °C
vapor density 
>1 (vs air)
vapor pressure 
< 1.33 hPa at 20 °C
refractive index 
n20/D 1.491
Flash point:
535 °F
storage temp. 
protect from light
solubility 
H2O: 0.005 M at 20 °C, clear, colorless
form 
Viscous Liquid
color 
≤100(APHA)
Odor
Odorless
PH Range
9.7
PH
6.5-8.5 (25℃)
Water Solubility 
Miscible with water.
Merck 
14,6761
BRN 
2315025
LogP
4.610 (est)
EPA Substance Registry System
Octoxynol 9 (9002-93-1)
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Safety

Hazard Codes 
Xi,Xn,N
Risk Statements 
41-36/38-22-51/53-36-36/37/38-37/38-52/53
Safety Statements 
26-39-36-61-36/39-36/37/39
RIDADR 
UN 3082 9/PG 3
WGK Germany 
3
RTECS 
WZ4750000
3
TSCA 
Yes
HazardClass 
9
PackingGroup 
III
HS Code 
34021300
Toxicity
LD50 oral in rat: 1800mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
X305
Product name
Triton™ X-305 solution
Purity
70% in H2O
Packaging
1gal
Price
$371
Updated
2024/03/01
Sigma-Aldrich
Product number
56741
Product name
IGEPAL® CA-630
Packaging
50mL
Price
$67.7
Updated
2024/03/01
Sigma-Aldrich
Product number
56741
Product name
IGEPAL® CA-630
Packaging
250ML
Price
$143
Updated
2024/03/01
Sigma-Aldrich
Product number
1477502
Product name
Octoxynol 9
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
200mg
Price
$474
Updated
2024/03/01
TCI Chemical
Product number
P0873
Product name
Polyethylene Glycol Mono-4-octylphenyl Ether (n=approx. 10)
Packaging
25g
Price
$27
Updated
2024/03/01
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Triton X-100 Chemical Properties,Usage,Production

Description

Triton X-100 is a nonionic surfactant that has a hydrophilic polyethylene oxide chain (on average it has 9.5 ethylene oxide units) and an aromatic hydrocarbon lipophilic or hydrophobic group. The hydrocarbon group is a 4-(1,1,3,3-tetramethylbutyl)-phenyl group. Triton X-100 is closely related to IGEPAL CA-630 or former Nonidet P-40, which might differ from it mainly in having slightly shorter ethylene oxide chains. Thus Triton X-100 is slightly more hydrophilic than Igepal CA-630; these two detergents may not be considered to be functionally interchangeable for most applications.
Triton X-100 is a common non-ionic surfactant and emulsifier which is often used in biochemical applications to solubilize proteins. It is considered a comparatively mild detergent, non-denaturing, and is reported in numerous references as a routinely added reagent. It is utilized for lysing cells to extract protein and cellular organelles. It can also permeabilize the living cell membrane for transfection.

Chemical Properties

Triton X-100 is a very stable material, assumed to be stable for years if stored sealed. It is a clear to slightly hazy, colorless to light yellow liquid (color by APHA = 100).
1. Specific gravity: 1.065 at 25°C (Approx. 1.07 g/mL).
2. Approximate molecular weight = 625, giving effective molarity = 1.7 M for the neat liquid.
3. UV absorption: lambda max = 275 nm and 283 nm in methanol.
4. Viscosity (Brookfield): 240 cps at 25°C.
5. pH (5% aqueous solution): 6.0 to 8.0.
6. Critical micelle concentration (CMC): 0.22 to 0.24 mM.

Uses

Nonionic detergent, emulsifier, dispersing agent. Octoxynol-9 as spermaticide.

Uses

Detergent, equivalent to Nonidet P-40.Triton X-100 is used as a non-ionic detergent, emulsifier and dispersing agent. It is useful for isolation of membrane proteins. It is also used in electrophoresis. It is an active ingredient in influenza vaccine (Fluzone). It finds applications in the dispersion of carbon materials for soft composite materials and restricting colony expansion in Aspergillus nidulans in microbiology. Further, it is an active ingredient in homemade vinyl record cleaning fluids together with distilled water and isopropyl alcohol.

Uses

Triton-X 100 is a non-ionic surfactant. Used in the enhancement of film porosity in conducting polymers.

Definition

ChEBI: A poly(ethylene glycol) terminated with a 4-(2,4,4-trimethylpentan-3-yl) phenyl group at one end.

brand name

Triton X-100 (Union Carbide).

General Description

Triton X-305 is a non-ionic surfactant. This octylphenol ethoxylate has higher number of ethylene oxide units, increased cmc (Critical micelle concentration) and hydrophile/lipophile balance when compared to Triton X-100. Triton X-305 is compatible with anionic, cationic, and other nonionic surfactants and chemically stable in most acidic and alkaline solutions.
Triton X-100 is a nonionic detergent, 100% active ingredient, which is often used in biochemical applications to solubilize proteins. Triton X-100 has no antimicrobial properties. It is considered a comparatively mild detergent, non-denaturing, and is reported in numerous references as a routinely added reagent. It does absorb in the ultraviolet region of the spectrum, however, so can interfere with protein quantitation. A number of polymeric resins have been used to remove X-100 from solution, including Amberlite hydrophobic XAD resins and Rezorian A161 cartridges. The &quot;X&quot; series of Triton detergents are produced from octylphenol polymerized with ethylene oxide. The number (&quot;-100&quot;) relates only indirectly to the number of ethylene oxide units in the structure. X100 has an &quot;average of 9.5&quot; ethylene oxide units per molecule, with an average molecular weight of 625. In addition, lower and higher mole adducts will be present in lesser amounts, varying slightly within supplier&#39;s standard manufacturing conditions. No antioxidants are added by Sigma or the manufacturer, but commercial preparations of Triton X-100 have been found to contain peroxides up to 0.22% hydrogen peroxide (H2O2) equivalents. These impurities may interfere with biological reactions. Sigma offers X-100-PC and X-100R-PC as biological grade alternatives.

Hazard

Triton X-100 is irritating to human skin and eyes, harmful if ingested and acutely toxic. It caused an increase in cellular and humoral immune responses in a 3-day intermittent skin study in mice, but there was no evidence of teratogenicity in rats.

Biological Activity

Triton X-100 causes a change in the fluorescence characteristics of the Tritoln X-100 effectively ruptures chloroplasts and reduces the electron flow required for the Hill reaction at low concentrations. Treatment of pea root cell preparations with Tritoln X-100 and low-speed centrifugation resulted in a pellet containing a large amount of stromal material (including RNA polymerase and DNA polymerase activity, most of the DNA, about 30% of the RNA, and 50% of the protein)[1-2].

Safety Profile

Moderately toxic by ingestion and intravenous routes. Experimental reproductive effects. Human mutation data reported. An eye and human skin irritant. Many glycol ethers cause dangerous human reproductive effects. When heated to decomposition it emits toxic fumes of NOx. A surfactant. See also GLYCOL ETHERS.

References

[1] L P VERNON; E S. Photochemical Activities of Spinach Chloroplasts Following Treatment with the Detergent Triton X-100.[J]. Plant Physiology, 1965. DOI:10.1104/pp.40.6.1269.
[2] BOTTOMLEY W. Some effects of triton x-100 on pea etioplasts.[J]. Plant Physiology, 1970. DOI:10.1104/pp.46.3.437.

Triton X-100 Preparation Products And Raw materials

Raw materials

Preparation Products

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Triton X-100 Suppliers

Hai 'an national strength chemical co. LTD
Tel
0513-88826680 13951428565
Email
13951428565@139.com
Country
China
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nantong chenrun chemical co.,ltd
Tel
+86-0513-88743581 +86-15358700783
Fax
0513-82971198
Email
chenrunchem@sina.com
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China
ProdList
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Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
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Hai'an County Guoli Chemical Co., Ltd.
Tel
0513-88826676 18862703018
Fax
0513-88867259
Email
liuminjin1118@163.com
Country
China
ProdList
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Nantong Yuanlai New Material Co., Ltd.
Tel
15151302905
Email
yuanlai20210628@163.com
Country
China
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Hubei XinghengKang Chemical Technology Co., Ltd.
Tel
027-88878869 18162384755
Fax
027-88878869
Email
xhkhu2014@163.com
Country
China
ProdList
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Biopole Pharmatech Co., Ltd.
Tel
0512-65974739-0 15151475053
Email
mengqi_biopole@163.com
Country
China
ProdList
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J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
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future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1995
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View Lastest Price from Triton X-100 manufacturers

Watson Biotechnology Co.,Ltd
Product
Triton x-100 9002-93-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20MT
Release date
2024-07-27
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Triton X-100 9002-93-1
Price
US $30.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000kg/Month
Release date
2024-04-28
Hebei Weibang Biotechnology Co., Ltd
Product
OCTYLPHENYLPOLYETHYLENE GLYCOL 9002-93-1
Price
US $100.00/KG
Min. Order
1KG
Purity
99%min
Supply Ability
200TON
Release date
2024-10-31

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