propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate
- Product Name
- propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate
- CAS No.
- 1421-14-3
- Chemical Name
- propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate
- Synonyms
- Epontol;WH-5668;TH-2180;FBA-1420;BAY-1420;Fabantol;Fabontal;Sombrevin;propanidid;Bayer-1420
- CBNumber
- CB0875008
- Molecular Formula
- C18H27NO5
- Formula Weight
- 337.41
- MOL File
- 1421-14-3.mol
propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate Property
- Boiling point:
- bp0.7 210-212°
- Density
- 1.2043 (rough estimate)
- refractive index
- 1.5000 (estimate)
- storage temp.
- Refrigerator
- solubility
- DMSO (Slightly), Ethyl Acetate (Slightly)
- form
- Oil
- color
- Pale Yellow to Yellow
- EPA Substance Registry System
- Propanidid (1421-14-3)
Safety
- Toxicity
- LD50 orally in rats: >10,000 mg/kg (Goldenthal)
N-Bromosuccinimide Price
- Product number
- S676765
- Product name
- Sombrevin
- Packaging
- 25mg
- Price
- $85
- Updated
- 2021/12/16
- Product number
- API0015482
- Product name
- PROPANIDID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $502.28
- Updated
- 2021/12/16
- Product number
- 61759
- Product name
- Sombrevin
- Packaging
- 5G
- Price
- $2200
- Updated
- 2021/12/16
- Product number
- API0015482
- Product name
- PROPANIDID
- Purity
- 95.00%
- Packaging
- 25G
- Price
- $5649
- Updated
- 2021/12/16
propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate Chemical Properties,Usage,Production
Chemical Properties
yellow oil bp0.7 210-212°C soluble in alcohol, chloroform, essentially water insoluble anasthetic Epontol (Bayer) Sombrevin
Uses
Anesthetic (intravenous).
Uses
Sombrevin, is an ultra short-acting phenylacetate general anesthetic.
Definition
ChEBI: Propanidid is a member of methoxybenzenes.
brand name
Epontol (Farbenfabriken Bayer A.G., Germany).
Clinical Use
Propanidid is used as a very short- to shortacting intravenous anesthetic for minor surgery and gynecology. It is characterized by rapid onset of and quick recovery from anesthesia, producing surgical anesthesia for 3 – 4 min. Repeated injections can be used to prolong the anesthesia. Postanesthetic sleep does not occur because the propyl ester is hydrolyzed rapidly in the patient to form inactive 3-methoxy-4- (N,N-diethylcarbamoylmethoxy)phenylacetic acid. After 20 – 30 min the patients generally are completely responsive .
Synthesis
Propanidid , propyl 3-
methoxy-4-(N,N-diethylcarbamoylmethoxy)-
phenylacetate, is a colorless to pale
yellowish water-insoluble oil. It is prepared
from the propyl ester of sodium homovanillic
acid and N,N-diethylchloroacetamide .
propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate Preparation Products And Raw materials
Raw materials
Preparation Products
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