CARBOCROMENE HYDROCHLORIDE
- Product Name
- CARBOCROMENE HYDROCHLORIDE
- CAS No.
- 655-35-6
- Chemical Name
- CARBOCROMENE HYDROCHLORIDE
- Synonyms
- Carboc;antiangor;Aids126445;intercordin;Aids-126445;Karbokromen;carbocromene;chromonar HCl;intensain hydrochloride;CARBOCROMENE HYDROCHLORIDE
- CBNumber
- CB0875578
- Molecular Formula
- C20H28ClNO5
- Formula Weight
- 397.89302
- MOL File
- 655-35-6.mol
CARBOCROMENE HYDROCHLORIDE Property
- Melting point:
- 159-160°
- solubility
- Chloroform (Slightly), Methanol (Slightly), Water (Slightly)
- form
- Solid
- color
- White to Off-White
Safety
- Toxicity
- LD50 in mice (g/kg): 6.3 orally; 0.528 i.p.; 0.0355 i.v. (Nitz, Potzch)
N-Bromosuccinimide Price
- Product number
- C432685
- Product name
- ChromonarHydrochloride
- Packaging
- 100mg
- Price
- $545
- Updated
- 2021/12/16
- Product number
- FC20422
- Product name
- Chromonar hydrochloride
- Packaging
- 100mg
- Price
- $840
- Updated
- 2021/12/16
- Product number
- FC20422
- Product name
- Chromonar hydrochloride
- Packaging
- 250mg
- Price
- $1530
- Updated
- 2021/12/16
- Product number
- FC20422
- Product name
- Chromonar hydrochloride
- Packaging
- 10mg
- Price
- $139.8
- Updated
- 2021/12/16
- Product number
- FC20422
- Product name
- Chromonar hydrochloride
- Packaging
- 25mg
- Price
- $254.5
- Updated
- 2021/12/16
CARBOCROMENE HYDROCHLORIDE Chemical Properties,Usage,Production
Originator
Intensain,Hoechst,Switz,1963
Uses
Vasodilator (coronary).
Definition
ChEBI: Carbocromen hydrochloride is a member of coumarins.
Manufacturing Process
18.7 g of 3β-diethylaminoethyl-4-methyl-7-hydroxy-coumarin chlorhydrate are
dissolved in 200 cc methyl ethyl ketone and 18 g anhydrous potassium
carbonate are added. The mixture is stirred for 1 hour at 70°C and then 12 g
bromoacetic acid ethyl ester are allowed to drop in. The reaction mixture is
stirred under reflux for 9 hours and then it is filtered off with suction in the
heat. The filtrate is concentrated in the vacuum to dryness and the resultant
residue is dissolved in ether. The etheric solution is washed with diluted
caustic soda solution for several times and, subsequently, dried with Glauber's
salt. By introduction of hydrochloric acid gas into the etheric solution the
reaction product is precipitated in the form of chlorhydrate. Yield: 15 g of 3β-
diethylaminoethyl-4-methylcoumarin-7-ethyl oxyacetate chlorhydrate having a
melting point of 154° to 156°C (= 63% of the theory).
The starting material is produced by reacting resorcinol with 2-(2-
diethylaminoethyl)acetic acid ethyl ester.
Therapeutic Function
Coronary vasodilator
CARBOCROMENE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from CARBOCROMENE HYDROCHLORIDE manufacturers
- Product
- CARBOCROMENE HYDROCHLORIDE 655-35-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2019-12-26