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CARBOCROMENE HYDROCHLORIDE

Product Name
CARBOCROMENE HYDROCHLORIDE
CAS No.
655-35-6
Chemical Name
CARBOCROMENE HYDROCHLORIDE
Synonyms
Carboc;antiangor;Aids126445;intercordin;Aids-126445;Karbokromen;carbocromene;chromonar HCl;intensain hydrochloride;CARBOCROMENE HYDROCHLORIDE
CBNumber
CB0875578
Molecular Formula
C20H28ClNO5
Formula Weight
397.89302
MOL File
655-35-6.mol
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CARBOCROMENE HYDROCHLORIDE Property

Melting point:
159-160°
solubility 
Chloroform (Slightly), Methanol (Slightly), Water (Slightly)
form 
Solid
color 
White to Off-White
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Safety

Toxicity
LD50 in mice (g/kg): 6.3 orally; 0.528 i.p.; 0.0355 i.v. (Nitz, Potzch)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
C432685
Product name
ChromonarHydrochloride
Packaging
100mg
Price
$545
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC20422
Product name
Chromonar hydrochloride
Packaging
100mg
Price
$840
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC20422
Product name
Chromonar hydrochloride
Packaging
250mg
Price
$1530
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC20422
Product name
Chromonar hydrochloride
Packaging
10mg
Price
$139.8
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC20422
Product name
Chromonar hydrochloride
Packaging
25mg
Price
$254.5
Updated
2021/12/16
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CARBOCROMENE HYDROCHLORIDE Chemical Properties,Usage,Production

Originator

Intensain,Hoechst,Switz,1963

Uses

Vasodilator (coronary).

Definition

ChEBI: Carbocromen hydrochloride is a member of coumarins.

Manufacturing Process

18.7 g of 3β-diethylaminoethyl-4-methyl-7-hydroxy-coumarin chlorhydrate are dissolved in 200 cc methyl ethyl ketone and 18 g anhydrous potassium carbonate are added. The mixture is stirred for 1 hour at 70°C and then 12 g bromoacetic acid ethyl ester are allowed to drop in. The reaction mixture is stirred under reflux for 9 hours and then it is filtered off with suction in the heat. The filtrate is concentrated in the vacuum to dryness and the resultant
residue is dissolved in ether. The etheric solution is washed with diluted caustic soda solution for several times and, subsequently, dried with Glauber's salt. By introduction of hydrochloric acid gas into the etheric solution the reaction product is precipitated in the form of chlorhydrate. Yield: 15 g of 3β- diethylaminoethyl-4-methylcoumarin-7-ethyl oxyacetate chlorhydrate having a melting point of 154° to 156°C (= 63% of the theory).
The starting material is produced by reacting resorcinol with 2-(2- diethylaminoethyl)acetic acid ethyl ester.

Therapeutic Function

Coronary vasodilator

CARBOCROMENE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Ethyl acetoacetate 7-hydroxy-4-methyl coumarin Acetoxyacetic acid CHLOROETHANE Resorcinol Ethyl chloroacetate

Preparation Products

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CARBOCROMENE HYDROCHLORIDE Suppliers

Canada 1 China 5 India 1 United Kingdom 1 United States 2 Global 10
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View Lastest Price from CARBOCROMENE HYDROCHLORIDE manufacturers

Career Henan Chemical Co
Product
CARBOCROMENE HYDROCHLORIDE 655-35-6
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2019-12-26

655-35-6, CARBOCROMENE HYDROCHLORIDERelated Search:

CHEMBRDG-BB 6149363 Cloricromenehydrochloride CARBOCROMEN (3-METHOXYPHENOXY) ACETIC ACID ETHYL ESTER 7-(CARBOXYMETHOXY)-4-METHYLCOUMARIN Cloricromene 3-[2-(DIETHYLAMINO)ETHYL]-7-HYDROXY-4-METHYLCOUMARIN HYDROCHLORIDE (4-METHYLPHENOXY) ACETIC ACID ETHYL ESTER CARBOCROMENE HYDROCHLORIDE

  • CARBOCROMENE HYDROCHLORIDE
  • ethyl [[3-[2-(diethylamino)ethyl]-4-methyl-2-oxo-2H-1-benzopyran-7-yl]oxy]acetate hydrochloride
  • 3-(beta-diethylaminoethyl)-4-methyl-7-(carbethoxymethoxy)-coumarin hydrochlor
  • antiangor
  • carbochromene hydrochloride
  • carbocromene
  • intensain hydrochloride
  • intercordin
  • 3[2-(N,N-Diethylamino)ethyl]-4-methyl-2-oxo-2H-1-benzopyran-7-yloxyacetic acid ethanol ether
  • Acetic acid, {[[3-[2-(diethylamino)ethyl]-4-methyl-2-oxo-2H-1-benzopyran-7-yl]ox} Y\]-, ethyl ester, hydrochloride
  • Aids126445
  • Aids-126445
  • 2-[[3-[2-(DiethylaMino)ethyl]-4-Methyl-2-oxo-2H-1-benzopyran-7-yl]oxy]acetic Acid Ethyl Ester Hydrochloride
  • 3-(2-DiethylaMinoethyl)-4-Methyl-7-carbethoxyMethoxy -2-oxo-1,2-chroMene Hydrochloride
  • Carboc
  • CarbochroMen Hydrochloride
  • ethyl 2-({3-[2-(diethylamino)ethyl]-4-methyl-2-oxo-2H-c hromen-7-yl}oxy)acetate hydrochloride
  • chromonar HCl
  • Karbokromen
  • 655-35-6
  • C20H27NO5HCl
  • Amines
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals