clofexamide
- Product Name
- clofexamide
- CAS No.
- 1223-36-5
- Chemical Name
- clofexamide
- Synonyms
- ANP246;NP-246;IEM-455;ANP 246;ANP-246;clofexamide;Chlofexamide;Amichlophene;2-(4-Chlorophenoxy)-N-[2-(diethylamino)ethyl]acetamide;Acetamide, 2-(4-chlorophenoxy)-N-[2-(diethylamino)ethyl]-
- CBNumber
- CB0884312
- Molecular Formula
- C14H21ClN2O2
- Formula Weight
- 284.78
- MOL File
- 1223-36-5.mol
clofexamide Property
- Melting point:
- 45 °C
- Boiling point:
- 124.5°C (rough estimate)
- Density
- 1.1742 (rough estimate)
- refractive index
- 1.5200 (estimate)
- pka
- 14.19±0.46(Predicted)
Safety
- Toxicity
- LD50 oral in rat: 1040mg/kg
N-Bromosuccinimide Price
- Product number
- API0011096
- Product name
- CLOFEXAMIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $501.37
- Updated
- 2021/12/16
clofexamide Chemical Properties,Usage,Production
Originator
Clofexamide ,CNRS
Manufacturing Process
In 1 L of water there is dissolved 116.0 g (1 mole) of N,Ndiethylethylenediamine and, under vigorous stirring at a temperature maintained below 50°C, there is added 205.0 g (1 mole) of the chloride of pchlorphenoxyacetic acid. The solution becomes rapidly homogeneous; the formation of the basic amide hydrochloride is rapidly completed by further stirring the reaction mixture for 2 h at about 20°C. Then an excess of soda lye is added and the basic amide formed is extracted by ether. The ethereal solution is dried on anhydrous sodium sulfate and ether is distilled after that the residue is dried. So 2-(p-chlorophenoxy)-N-(2-(diethylamino)ethyl) acetamide is obtained.
Therapeutic Function
Antidepressant, Analgesic, Antiinflammatory, Local anesthetic
clofexamide Preparation Products And Raw materials
Raw materials
Preparation Products
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