CLOFEZONE
- Product Name
- CLOFEZONE
- CAS No.
- 60104-29-2
- Chemical Name
- CLOFEZONE
- Synonyms
- CLOFEZONE
- CBNumber
- CB4511715
- Molecular Formula
- C33H41ClN4O4
- Formula Weight
- 593.17
- MOL File
- 60104-29-2.mol
CLOFEZONE Property
- pka
- pKa 4.5(H2O t unde?ned I unde?ned) (Uncertain)
CLOFEZONE Chemical Properties,Usage,Production
Originator
Perclusone,Anphar-Rolland,France,1967
Manufacturing Process
935 g of phenylbutazone are dissolved, with heating to a lukewarm state, in 2.7 liters of acetone containing 20% water, and the mixture is filtered if necessary. 853.5 g of p-chlorophenoxyacetic acid diethylamino ethylamide are dissolved in 300 cc of acetone containing 20% water, and the solution is poured into the phenylbutazone solution. There is slight heating, and the solution clarifies. The salt crystallizes rapidly. Drying is effected on a Buchner funnel and the mixture is washed in 450 cc of acetone containing 20% of water. The 1,702 g of product obtained is recrystallized in 2,450 cc of acetone containing 20% of water and, after drying in an oven at 37°C, 1,585 g (86%) of product are obtained. The product is in the form of a white crystalline powder having a melting point of from 87° to 89°C in the Maquenne block.
Therapeutic Function
Analgesic, Antiinflammator
CLOFEZONE Preparation Products And Raw materials
Raw materials
Preparation Products
CLOFEZONE Suppliers
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- China
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- Country
- Germany
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- Country
- United States
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