ChemicalBook > CAS DataBase List > 2S,4R-Sacubitril
2S,4R-Sacubitril
- Product Name
- 2S,4R-Sacubitril
- CAS No.
- 2307668-79-5
- Chemical Name
- 2S,4R-Sacubitril
- Synonyms
- Sacubitril Impurity 71;Sacubitril Impurity 121;[1,1'-Biphenyl]-4-pentanoic acid, γ-[(3-carboxy-1-oxobutyl)amino]-α-methyl-, 4-ethyl ester, (αR,γS)-rel-
- CBNumber
- CB09272710
- Molecular Formula
- C25H31NO5
- Formula Weight
- 425.53
- MOL File
- 2307668-79-5.mol
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2S,4R-Sacubitril Property
- Boiling point:
- 658.5±55.0 °C(Predicted)
- Density
- 1.136±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 4.76±0.10(Predicted)
- form
- Oil
- color
- Colorless to light yellow
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N-Bromosuccinimide Price
A2B
- Product number
- BA33135
- Product name
- 2S,4R-Sacubitril
- Purity
- 99%
- Packaging
- 1mg
- Price
- $685
- Updated
- 2021/12/16
A2B
- Product number
- BA33135
- Product name
- 2S,4R-Sacubitril
- Purity
- 99%
- Packaging
- 5mg
- Price
- $2035
- Updated
- 2021/12/16
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2S,4R-Sacubitril Chemical Properties,Usage,Production
Description
2S,4R-Sacubitril is the impurity of Sacubitril. Sacubitril is approved by the Food and Drug Administration for use in combination with valsartan for the treatment of patients with heart failure.
Uses
2S,4R-Sacubitril is the impurity of Sacubitril. Sacubitril is approved by the Food and agent Administration for use in combination with valsartan for the treatment of patients with heart failure.
References
[1]. Shi J, et al. Sacubitril Is Selectively Activated by Carboxylesterase 1 (CES1) in the Liver and the Activation Is Affected by CES1 Genetic Variation. Drug Metab Dispos. 2016 Apr;44(4):554-9.
2S,4R-Sacubitril Preparation Products And Raw materials
Raw materials
Preparation Products
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2S,4R-Sacubitril Suppliers
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