Sacubitril Sodium

Product Name: Sacubitril Sodium
CAS No.: 149690-05-1
Chemical Name: Sacubitril Sodium
Synonyms: Sacubitril sodium;Valsartan Sodium;Thacubatra sodium;AHU-377 sodium salt;Sacubitril Sodium Salt;AHU-377 (Sacubitril free base);Sodium,4-[[(2S,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoate;sodium 4-(((2S,4R)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoate;(αR,γS)- γ-[(3-Carboxy -1-oxopropyl) amino]-methyl-[1,1'-biphenyl]-4-pentanoic acid 4-ethyl ester sodium salt
CBNumber: CB03069990
Molecular Formula: C24H28NNaO5
Formula Weight: 433.47259
MOL File: 149690-05-1.mol

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Sacubitril Sodium Property

Melting point:: 163-165°C
storage temp.: -20°C, Hygroscopic
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
color: White to Off-White
Stability:: Hygroscopic

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H319Causes serious eye irritation

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

DC Chemicals

Product number: DC32235
Product name: Sacubitrilsodium
Packaging: 250mg
Price: $700
Updated: 2021/12/16

DC Chemicals

Product number: DC32235
Product name: Sacubitrilsodium
Packaging: 1g
Price: $1400
Updated: 2021/12/16

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Sacubitril Sodium Chemical Properties,Usage,Production

Description

Sacubitril Sodium is a potent orally active NEP (enkephalinase) inhibitor with an IC50 of 5 nM. Sacubitril Sodium enhances the tone of the natriuretic peptide (NP) system and exerts significant antihypertensive effects. Sacubitril Sodium is a component of the heart failure drug LCZ696. Sacubitril Sodium is used in heart failure, hypertension and COVID-19 studies.

Uses

Sacubitril Sodium Salt is a salt of Sacubitril, an antihypertensive drug used in combination with valsartan. The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure.

Sacubitril Sodium Preparation Products And Raw materials

Raw materials

Preparation Products

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Sacubitril Sodium Suppliers

China 61 India 11 United States 4 Global 76

CHANGZHOU PHARMACEUTICAL FACTORY

Tel: 519-88821493 18915891730
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Hubei Weideli Chemical Reagent Co.，Ltd.

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Jiangxi ravel Biotechnology Co.,Ltd

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Hubei Chenxin Pharmaceutical Co., Ltd.

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Shanghai Pansopharm Technology Co., Ltd.

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INTERCHEMIE NANJING PHARMATECH CO., LTD

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Shanghai QianYan Bio-technology Co., Ltd

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ShangHai Biochempartner Co.,Ltd

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Wuhan Wsem Biological Co., Ltd.

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Wellman Pharmaceutical Group Limited

Tel: 027-027-83778875 15807197853
Fax: 027-83991220
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149690-05-1, Sacubitril Sodium Related Search:

LCZ696(valsartan + sacubitril) impurity 35 [1,1′-Biphenyl]-4-pentanoic acid, γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl-, 4-methyl ester, calcium salt (2:1), (αR,γS)- LCZ696(valsartan + sacubitril) impurity 31 [1,1'-Biphenyl]-4-pentanoic acid, γ-(acetylamino)-α-methyl-, (αR,γS)- LCZ696(valsartan + sacubitril) impurity 34 2S,4R-Sacubitril Sacubatrava valsartan sodium hydrate Sacubitril Impurity 43 Sacubitril Methyl esterQ: What is Sacubitril Methyl ester Q: What is the CAS Number of Sacubitril Methyl ester Sacubitrilat-d5

Sacubitril Sodium Salt

Sacubitril sodium

Valsartan Sodium

sodium 4-(((2S,4R)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoate

AHU-377 (Sacubitril free base)

AHU-377 sodium salt

Sodium,4-[[(2S,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoate

Thacubatra sodium

(αR,γS)- γ-[(3-Carboxy -1-oxopropyl) amino]-methyl-[1,1'-biphenyl]-4-pentanoic acid 4-ethyl ester sodium salt

149690-05-1