ChemicalBook > CAS DataBase List > 2S,4R-Sacubitril
2S,4R-Sacubitril
- Product Name
- 2S,4R-Sacubitril
- CAS No.
- 2307668-79-5
- Chemical Name
- 2S,4R-Sacubitril
- Synonyms
- [1,1'-Biphenyl]-4-pentanoic acid, γ-[(3-carboxy-1-oxobutyl)amino]-α-methyl-, 4-ethyl ester, (αR,γS)-rel-
- CBNumber
- CB09272710
- Molecular Formula
- C25H31NO5
- Formula Weight
- 425.53
- MOL File
- 2307668-79-5.mol
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2S,4R-Sacubitril Property
- Boiling point:
- 658.5±55.0 °C(Predicted)
- Density
- 1.136±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 4.76±0.10(Predicted)
- form
- Oil
- color
- Colorless to light yellow
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N-Bromosuccinimide Price
A2B
- Product number
- BA33135
- Product name
- 2S,4R-Sacubitril
- Purity
- 99%
- Packaging
- 1mg
- Price
- $685
- Updated
- 2021/12/16
A2B
- Product number
- BA33135
- Product name
- 2S,4R-Sacubitril
- Purity
- 99%
- Packaging
- 5mg
- Price
- $2035
- Updated
- 2021/12/16
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2S,4R-Sacubitril Chemical Properties,Usage,Production
Description
2S,4R-Sacubitril is the impurity of Sacubitril. Sacubitril is approved by the Food and Drug Administration for use in combination with valsartan for the treatment of patients with heart failure.
References
[1]. Shi J, et al. Sacubitril Is Selectively Activated by Carboxylesterase 1 (CES1) in the Liver and the Activation Is Affected by CES1 Genetic Variation. Drug Metab Dispos. 2016 Apr;44(4):554-9.
2S,4R-Sacubitril Preparation Products And Raw materials
Raw materials
Preparation Products
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2S,4R-Sacubitril Suppliers
- Tel
- 010-60605840 15801484223;
- psaitong@jm-bio.com
- Country
- China
- ProdList
- 29774
- Advantage
- 58
- Tel
- 010-50973130 17801761073
- Gsiyu@solarbio.com
- Country
- China
- ProdList
- 50464
- Advantage
- 58
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