2S,4R-Sacubitril

Product Name: 2S,4R-Sacubitril
CAS No.: 2307668-79-5
Chemical Name: 2S,4R-Sacubitril
Synonyms: [1,1'-Biphenyl]-4-pentanoic acid, γ-[(3-carboxy-1-oxobutyl)amino]-α-methyl-, 4-ethyl ester, (αR,γS)-rel-
CBNumber: CB09272710
Molecular Formula: C25H31NO5
Formula Weight: 425.53
MOL File: 2307668-79-5.mol

More

Less

2S,4R-Sacubitril Property

Boiling point:: 658.5±55.0 °C(Predicted)
Density: 1.136±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
pka: 4.76±0.10(Predicted)

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

A2B

Product number: BA33135
Product name: 2S,4R-Sacubitril
Purity: 99%
Packaging: 1mg
Price: $685
Updated: 2021/12/16

A2B

Product number: BA33135
Product name: 2S,4R-Sacubitril
Purity: 99%
Packaging: 5mg
Price: $2035
Updated: 2021/12/16

More

Less

2S,4R-Sacubitril Chemical Properties,Usage,Production

Description

2S,4R-Sacubitril is the impurity of Sacubitril. Sacubitril is approved by the Food and Drug Administration for use in combination with valsartan for the treatment of patients with heart failure.

References

[1]. Shi J, et al. Sacubitril Is Selectively Activated by Carboxylesterase 1 (CES1) in the Liver and the Activation Is Affected by CES1 Genetic Variation. Drug Metab Dispos. 2016 Apr;44(4):554-9.

2S,4R-Sacubitril Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

2S,4R-Sacubitril Suppliers

China 2 United States 1 Global 3

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 29778
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 17801761073
Email: Gsiyu@solarbio.com
Country: China
ProdList: 50471
Advantage: 58

2307668-79-5, 2S,4R-SacubitrilRelated Search:

LCZ696(valsartan + sacubitril) impurity 35 [1,1′-Biphenyl]-4-pentanoic acid, γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl-, 4-methyl ester, calcium salt (2:1), (αR,γS)- LCZ696(valsartan + sacubitril) impurity 31 [1,1'-Biphenyl]-4-pentanoic acid, γ-(acetylamino)-α-methyl-, (αR,γS)- LCZ696(valsartan + sacubitril) impurity 34 Sacubatrava valsartan sodium hydrate Sacubitril Impurity 43 Sacubitril Sodium Sacubitril Methyl esterQ: What is Sacubitril Methyl ester Q: What is the CAS Number of Sacubitril Methyl ester Sacubitrilat-d5

[1,1'-Biphenyl]-4-pentanoic acid, γ-[(3-carboxy-1-oxobutyl)amino]-α-methyl-, 4-ethyl ester, (αR,γS)-rel-

2307668-79-5