Selamectin
- Product Name
- Selamectin
- CAS No.
- 220119-17-5
- Chemical Name
- Selamectin
- Synonyms
- Skudin;Stronghold;Selamectin;Selamection;Selamectin（b）;Selamectin CRS;hypnocarpic acid;Sierra rhzomorph;selamectin ceutical;Selamectin (1611729)
- CBNumber
- CB0947411
- Molecular Formula
- C43H63NO11
- Formula Weight
- 769.97
- MOL File
- 220119-17-5.mol
Selamectin Property
- Melting point:
- >180°C
- Boiling point:
- 917.0±65.0 °C(Predicted)
- Density
- 1.35±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform (Slightly), Dichloromethane (Slightly, Heated), DMSO (Slightly)
- pka
- 10.34±0.70(Predicted)
- color
- White to Yellow
- Stability:
- Hygroscopic
- InChIKey
- AFJYYKSVHJGXSN-KAJWKRCWSA-N
- CAS DataBase Reference
- 220119-17-5
Safety
- WGK Germany
- 3
- HS Code
- 2932206000
N-Bromosuccinimide Price
- Product number
- 32476
- Product name
- Selamectin
- Purity
- VETRANAL
- Packaging
- 10mg
- Price
- $575
- Updated
- 2024/03/01
- Product number
- 1611729
- Product name
- Selamectin
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 350mg
- Price
- $2150
- Updated
- 2024/03/01
- Product number
- 21529
- Product name
- Selamectin
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 21529
- Product name
- Selamectin
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $122
- Updated
- 2024/03/01
- Product number
- 21529
- Product name
- Selamectin
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $184
- Updated
- 2024/03/01
Selamectin Chemical Properties,Usage,Production
Description
Selamectin is formulated as a spot-on for cats and dogs to control fleas (Ctenocephalides spp.) and flea-allergy dermatitis, to prevent heartworm disease, and to control ear mites (Otodectes cynotes) in cats and dogs. It is also approved for the treatment and control of sarcoptic mange (Sarcoptes scabiei) in dogs and hookworms (Ancylostoma tubaeformis) and roundworms (Toxocara cati) in cats.
Description
Selamectin is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes. At 0.1 μg/ml, selamectin is reported to inhibit growth in an H. contortus larval development assay.
Uses
Selamectin is a topical parasiticide and also used as a veterinary antihelminithic agent on animals.
Uses
Selamectin is a semi-synthetic avermectin derivative prepared by selective hydrolysis and oximation of doramectin. Selamectin is a potent nematocide used for the treatment of endo- and exo- parasites of domestic animals, notably cats and dogs. Like the other milbemycin/avermectins, selamectin selectively binds to parasite glutamate-gated chloride ion channels and disrupts neurotransmission leading to paralysis and death of the parasite.
Definition
ChEBI: Selamectin is a milbemycin.
Veterinary Drugs and Treatments
Topical selamectin (Revolution?—Pfizer) is indicated for flea infestations (Ctenocephalides felis), prevention of heartworm disease (Dirofilaria immitis), and for ear mites (Otodectes cynotis) in both dogs and cats. Additionally in dogs, it is indicated for sarcoptic mange (Sarcoptes scabeii), and tick infestations (Dermacentor variabilis). In cats: hookworm (Ancylostoma tubaeforme) and roundworm (Toxocara cati). The product (Revolution?) is labeled as not effective against either adult heartworms or clearing circulating microfilaria, but it possibly may have some efficacy with prolonged, continuous administration (Atkins 2007b).
Toxicity evaluation
Acute oral LD50 for rats: >1,600 mg/kg
Selamectin Preparation Products And Raw materials
Raw materials
Preparation Products
Selamectin Suppliers
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View Lastest Price from Selamectin manufacturers
- Product
- Selamectin 220119-17-5
- Price
- US $0.00/Kg/Bag
- Min. Order
- 2Kg/Bag
- Purity
- 99% up, High Density
- Supply Ability
- 20 tons
- Release date
- 2022-08-26
- Product
- Selamectin 220119-17-5
- Price
- US $5.00/kg
- Min. Order
- 1kg
- Purity
- 99.92%
- Supply Ability
- 50000tons
- Release date
- 2024-04-23
- Product
- Selamectin 220119-17-5
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2024-04-08