ChemicalBook > CAS DataBase List > 5,7-DIMETHYLISATIN

5,7-DIMETHYLISATIN

Product Name: 5,7-DIMETHYLISATIN
CAS No.: 39603-24-2
Chemical Name: 5,7-DIMETHYLISATIN
Synonyms: AKOS BC-1645;5,7-Dimethylsatin;5,7-DIMETHYLISATIN;TIMTEC-BB SBB005805;5,7-dimethylisatine;5,7-Dimethylisatin,96%;5,7-Dimethylisatin,95%;5,7-dimethyl-indole-3-dione;5,7-dimethyl-indole-2,3-dione;5,7-DIMETHYL-2,3-INDOLINEDIONE
CBNumber: CB1100167
Molecular Formula: C10H9NO2
Formula Weight: 175.18
MOL File: 39603-24-2.mol

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5,7-DIMETHYLISATIN Property

Melting point:: 245 °C
Boiling point:: 306.47°C (rough estimate)
Density: 1.250
refractive index: 1.5060 (estimate)
storage temp.: Sealed in dry,Room Temperature
pka: 10.43±0.20(Predicted)
Appearance: Yellow to orange Solid
Water Solubility: Insoluble in water.
BRN: 143679
CAS DataBase Reference: 39603-24-2(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Safety Statements: 24/25-22
RTECS: NL7930000
HazardClass: IRRITANT
HS Code: 29337900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: D460028
Product name: 5,7-Dimethylisatin
Packaging: 100mg
Price: $75
Updated: 2021/12/16

ChemScene

Product number: CS-0037914
Product name: 5,7-Dimethyl-1H-indole-2,3-dione
Purity: 99.10%
Packaging: 10g
Price: $51
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD67956
Product name: 5,7-Dimethylisatin
Packaging: 5G
Price: $62.5
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD67956
Product name: 5,7-Dimethylisatin
Packaging: 10g
Price: $100
Updated: 2021/12/16

ChemScene

Product number: CS-0037914
Product name: 5,7-Dimethyl-1H-indole-2,3-dione
Purity: 99.10%
Packaging: 25g
Price: $110
Updated: 2021/12/16

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5,7-DIMETHYLISATIN Chemical Properties,Usage,Production

Chemical Properties

red to red-brown powder

Uses

5,7-Dimethylisatin is used to produce cyano-(5,7-dimethyl-2-oxo-1,2-dihydro-indol-3-ylidene)-acetic acid ethyl ester by knoevenagel condensation with cyanoacetic acid ethyl ester. It is an important raw material and intermediate used in organic synthesis, pharmaceuticals and agrochemicals.

Synthesis

7343-12-6

39603-24-2

The general procedure for the synthesis of 5,7-dimethylindoline-2,3-dione using (E)-N-(2,4-dimethylphenyl)-2-(hydroxyimino)acetamide as starting material was as follows: concentrated sulfuric acid (20 mL) was added to a 100 mL flask with vigorous stirring at 50°C, and N-2-(hydroxyimino)acetamide derivatives (7.0 g) were added in batches. The reaction temperature was maintained between 50°C and 75°C, followed by the addition of sulfide. After the addition was completed, the reaction mixture was warmed to 80°C and stirring was continued for 30 minutes. After completion of the reaction, the mixture was cooled to room temperature and slowly poured into ice (250 g). The precipitated solid was collected and dried in air to give the crude product. The crude product was dissolved in 5% dilute sodium hydroxide solution (100 mL) and acidified with 4N hydrochloric acid (20 mL). The precipitated solid was filtered and dried thoroughly to give the purified target compound 5,7-dimethylindoline-2,3-dione.

References

[1] Journal of Chemical Research, Miniprint, 1998, # 7, p. 1425 - 1434
[2] Medicinal Chemistry, 2016, vol. 12, # 5, p. 489 - 498
[3] Journal of Organic Chemistry, 1952, vol. 17, p. 149,153
[4] Proceedings of the Royal Society of London, Series B: Biological Sciences, 1958, vol. 148, p. 481,488
[5] Gazzetta Chimica Italiana, 1955, vol. 85, p. 840,841

5,7-DIMETHYLISATIN Preparation Products And Raw materials

Raw materials

Preparation Products

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5,7-DIMETHYLISATIN Suppliers

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View Lastest Price from 5,7-DIMETHYLISATIN manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 5,7-DIMETHYLISATIN 39603-24-2
Price: US $100.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-07

Zhuozhou Wenxi import and Export Co., Ltd

Product: 5,7-DIMETHYLISATIN 39603-24-2
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

Career Henan Chemical Co

Product: 5,7-DIMETHYLISATIN 39603-24-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2019-12-24

39603-24-2, 5,7-DIMETHYLISATINRelated Search:

5,6-Dimethylisatin 1,5-DIMETHYLINDOLINE-2,3-DIONE 4,5-Dimethylisatin 5,7-DIMETHYLISATIN AKOS BBS-00006012 AKOS BBS-00005452 AKOS BBS-00005449 AKOS BBS-00006009 AKOS BBS-00006008 AKOS BBS-00006010 AKOS BBS-00006007 6,7-dimethylisatin 4,7-Dimethylisatin 3,5-Dimethylisatoic anhydride AKOS BBS-00005493 AKOS BBS-00006004 AKOS BBS-00005465 AKOS BBS-00005459

TIMTEC-BB SBB005805

1H-Indole-2,3-dione,5,7-dimethyl-

5,7-dimethyl-1h-indole-2,3-dione

5,7-dimethyl-1h-indole-3-dione

5,7-dimethyl-indole-2,3-dione

5,7-dimethyl-indole-3-dione

5,7-Dimethylisatin,96%

5,7-DIMETHYL-2,3-INDOLINEDIONE

5,7-DIMETHYLISATIN

AKOS BC-1645

5,7-dimethyl-1H-indole-2,3-dione(SALTDATA: FREE)

5,7-Dimethylisatin,95%

5,7-Dimethylsatin

5,7-dimethylisatine

5,7-Dimethyl-1H-indol-2,3-dione

39603-24-2

C1OH9NO2

AMIDE

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