ChemicalBook > CAS DataBase List > Arteether

Arteether

Product Name
Arteether
CAS No.
75887-54-6
Chemical Name
Arteether
Synonyms
SM-22;SM-227;Areether;Arteethe;Arteether;Artemotil;ARPRINOCID;aArteether;NSC 665971;Beta-Arteether
CBNumber
CB11012009
Molecular Formula
C17H28O5
Formula Weight
312.4
MOL File
75887-54-6.mol
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Arteether Property

Melting point:
80-820C
alpha 
D21 +154.5° (c = 1.0 in CHCl3)
Boiling point:
372.4±42.0 °C(Predicted)
Density 
1.16±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly)
form 
Solid
color 
White
CAS DataBase Reference
75887-54-6
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H226Flammable liquid and vapour

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P370+P378In case of fire: Use … for extinction.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
11814
Product name
Arteether
Purity
≥95%
Packaging
5mg
Price
$77
Updated
2024/03/01
Cayman Chemical
Product number
11814
Product name
Arteether
Purity
≥95%
Packaging
10mg
Price
$144
Updated
2024/03/01
Cayman Chemical
Product number
11814
Product name
Arteether
Purity
≥95%
Packaging
25mg
Price
$340
Updated
2024/03/01
Cayman Chemical
Product number
11814
Product name
Arteether
Purity
≥95%
Packaging
50mg
Price
$602
Updated
2024/03/01
TRC
Product number
A774300
Product name
Arteether
Packaging
100mg
Price
$970
Updated
2021/12/16
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Arteether Chemical Properties,Usage,Production

Description

Arteether reached the market in the Netherlands as a solution in sesame oil, administered by i.m. injection, for the treatment of severe malaria infections in children and adolescents. Artheether, a sesquiterpene acetal with an endoperoxide bridge, is an ether derivative of the naturally occuring compound artemisinin, the active component of Chinese herbal remedies. As the other structural analogs of artemisinin, such as artesunate or artemether, it acts rapidly against Plasmodium, the parasite responsible for the disease, during the early blood stage of its development. It also exhibits a gametocytocidal activity against Plasmodium falciparum, reducing its potential for transmission. Because the only controlled clinical studies had been performed in children and adolescents, this new antimalarial drug was only approved for young patients. Further studies in adults treated with 150 mg i.m. artemotil, once daily for three consecutive days, indicated that the drug was efficient, rapidly acting (parasite clearance time meanly 38 h) and well tolerated. A new promising achievement in the regression of malaria is the combination of artemisinin derivatives with other long-lived antimalarials as mefloquine or pyrimethamine/sulfa.

Chemical Properties

White Crystalline Solid

Originator

Central Drug Research Institute (India)

Uses

Derivative of Artemisinin. Antimalarial

Definition

ChEBI: Artemotil is an artemisinin derivative.

brand name

Artemotil

Arteether Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Arteether manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Arteether 75887-54-6
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
1000kg
Release date
2021-09-15
NanJing Spring & Autumn Biological Engineering CO., LTD.
Product
Arteether 75887-54-6 75887-54-6
Price
US $6.50/mg
Min. Order
20mg
Purity
≥98%
Supply Ability
1000.00 kgs
Release date
2019-07-11
Qiuxian Baitai New Material Co., LTD
Product
Arteether 75887-54-6
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 tons
Release date
2021-03-11

75887-54-6, ArteetherRelated Search:


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  • dihydroqinghaosu ethyl ether
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  • 3,12-Epoxy-12H-pyrano(4,3-J)-1,2-benzodioxepin, 10-ethoxydecahydro-3,6,9-trimethyl-, (3S-(3alpha,5alpha,6alpha,8aalpha,9beta,10beta,12beta,12aalpha))-
  • AlphaBetaArteetherC17H28O5
  • Alpha Beta Arteether
  • aArteether
  • (3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-Ethoxydecahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin
  • Artemotil
  • SM-22
  • 10-Ethoxydecahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin
  • Arteether 75887-54-6
  • 3,12-Epoxy-12H-pyrano(4,3-J)-1,2-benzodioxepin, decahydro-10-ethoxy-3,6,9-trimethyl-, (3R-(3alpha,5abeta,6beta,8abeta,9alpha,10alpha,12beta,12ar*))-
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  • NSC 665971
  • Beta-Arteether
  • 3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin, 10-ethoxydecahydro-3,6,9-trimethyl-, (3R,5aS,6R,8aS,9R,10S,12R,12aR)-
  • (3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-ethoxy-3,6,9-trimethyldecahydro-3H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene
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  • 75887-54-6
  • C17H28O5
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