ChemicalBook > CAS DataBase List > Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI)

Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI)

Product Name
Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI)
CAS No.
225641-84-9
Chemical Name
Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI)
Synonyms
tert-Butyl ((1R,3S)-3-hydroxycyclopentyl)carbaMate;(1S,3R)-3-(Boc-amino)cyclopentanol;(3-Hydroxy-cyclopentyl)-carbamic acid tert-butyl ester;tert-Butyl ((1R,3S);-3-hydroxycyclopentyl);tert-butyl (1S,3R)-3-hydroxycyclopentylcarbamate;tert-butyl N-[(1R,3S)-3-hydroxycyclopentyl]carbamate;Benzoicacid,4-fluoro-,(5-bromo-5-methoxyphenyl)methylester;[(1R,3S)-3-Hydroxycyclopentyl]carbamic acid tert-butyl ester;Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester
CBNumber
CB11051327
Molecular Formula
C10H19NO3
Formula Weight
201.26
MOL File
225641-84-9.mol
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Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI) Property

Boiling point:
320.8±31.0 °C(Predicted)
Density 
1.08±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
pka
12.27±0.40(Predicted)
Appearance
Off-white to light yellow Solid
optical activity
Consistent with structure
InChI
InChI=1S/C10H19NO3/c1-10(2,3)14-9(13)11-7-4-5-8(12)6-7/h7-8,12H,4-6H2,1-3H3,(H,11,13)/t7-,8+/m1/s1
InChIKey
SBUKINULYZANSP-SFYZADRCSA-N
SMILES
C(OC(C)(C)C)(=O)N[C@@H]1CC[C@H](O)C1
CAS DataBase Reference
225641-84-9
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

SynQuest Laboratories
Product number
4256-1-54
Product name
tert-Butyl N-[(1R,3S)-3-hydroxycyclopentyl]carbamate
Purity
97.0%
Packaging
250mg
Price
$290
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CCH0030964
Product name
[(1R,3S)-3-HYDROXYCYCLOPENTYL]-CARBAMIC ACID-1,1-DIMETHYLETHYL ESTER
Purity
95.00%
Packaging
5MG
Price
$495.34
Updated
2021/12/16
Matrix Scientific
Product number
122499
Product name
tert-Butyl((1R,3S)-3-hydroxycyclopentyl)carbamate
Purity
97.0%
Packaging
1g
Price
$594
Updated
2021/12/16
SynQuest Laboratories
Product number
4256-1-54
Product name
tert-Butyl N-[(1R,3S)-3-hydroxycyclopentyl]carbamate
Purity
97.0%
Packaging
1g
Price
$790
Updated
2021/12/16
AK Scientific
Product number
4732AQ
Product name
Tert-Butyl(1R,3S)-3-Hydroxycyclopentylcarbamate
Packaging
250mg
Price
$213.2
Updated
2021/12/16
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Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI) Chemical Properties,Usage,Production

Uses

Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI) is carboxylic acid ester organic compounds, which can be used as pharmaceutical intermediates.

Synthesis

201054-55-9

225641-84-9

General procedure for the synthesis of tert-butyl ((1R,3S)-3-hydroxycyclopentyl)carbamate from (1S,4R)-4-cyclopenten-1-ol-2-amino-tert-butyloxycarbonyl: Tert-butyl (1S,4R)-4-hydroxycyclopent-2-enylcarbamate (2.0 g, 10 mmol) was dissolved in methanol (20 mL), and the reaction flask was subjected to three times nitrogen Displacement. 10% Pd/C catalyst (0.2 g, 10%, w/w) was added to the above solution, followed by three displacements with hydrogen. The reaction mixture was stirred at room temperature and hydrogen atmosphere (1 atm) for 14 hours. Upon completion of the reaction, the catalyst was removed by diatomaceous earth filtration. The filtrate was concentrated to afford the target product ((1R,3S)-3-hydroxycyclopentyl)carbamic acid tert-butyl ester (1.9 g, yield: 95%).

References

[1] Patent: US2016/200730, 2016, A1. Location in patent: Paragraph 0500; 0501

Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

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Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI) Suppliers

Suzhou MgPlus Pharmtech Co., Ltd.
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0512-66727658 18115508618
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China
ProdList
1159
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58
Beijing Ouhe Technology Co., Ltd
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010-010-82967028 13522913783
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+86-10-82967029
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China
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+86-21-61294319
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sales@topbiochem.com
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China
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Shanghai Jian Chao Chemical Technology Co., Ltd.
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150-2103-5486 18017383231
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Bide Pharmatech Ltd.
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Chengdu Firster Pharmaceutical Co., Ltd.
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028-87078428 028-87074958
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8772-8116
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China
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2598
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Shanghai Balmxy Pharmaceutical Co., Ltd
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021-24206007 13764915196
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86-021-23027023
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Shanghai AQBioPharma Co., Ltd.
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51370935-8011
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View Lastest Price from Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI) manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
TERT-BUTYL ((1R,3S)-3-HYDROXYCYCLOPENTYL)CARBAMATE 225641-84-9
Price
US $3.00-9.00/KG
Min. Order
0.1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2025-06-24

225641-84-9, Carbamic acid, [(1R,3S)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI)Related Search:


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