2-Pyrimidinamine, N-methyl- (9CI)
- Product Name
- 2-Pyrimidinamine, N-methyl- (9CI)
- CAS No.
- 931-61-3
- Chemical Name
- 2-Pyrimidinamine, N-methyl- (9CI)
- Synonyms
- NSC 102272;N-Methyl-2-pyrimidinamine;2-PyriMidinaMine, N-Methyl-;methyl(pyrimidin-2-yl)amine;2-Pyrimidinamine, N-methyl- (9CI);2-Pyrimidinamine, N-methyl- (9CI) ISO 9001：2015 REACH
- CBNumber
- CB11081371
- Molecular Formula
- C5H7N3
- Formula Weight
- 109.13
- MOL File
- 931-61-3.mol
2-Pyrimidinamine, N-methyl- (9CI) Property
- Melting point:
- 60-62℃
- Boiling point:
- 216℃
- Density
- 1.144
- Flash point:
- 85℃
- storage temp.
- 2-8°C(protect from light)
- form
- Solid
- pka
- 3.90±0.10(Predicted)
- Appearance
- White to yellow Solid
- InChI
- InChI=1S/C5H7N3/c1-6-5-7-3-2-4-8-5/h2-4H,1H3,(H,6,7,8)
- InChIKey
- BQNXHDSGGRTFNX-UHFFFAOYSA-N
- SMILES
- C1(NC)=NC=CC=N1
Safety
- HS Code
- 2933599590
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- M103138
- Product name
- N-methylpyrimidin-2-amine
- Packaging
- 5mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- M103138
- Product name
- N-methylpyrimidin-2-amine
- Packaging
- 10mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- CS-0061723
- Product name
- N-Methylpyrimidin-2-amine
- Packaging
- 250mg
- Price
- $71
- Updated
- 2021/12/16
- Product number
- J55249
- Product name
- 2-(Methylamino)pyrimidine
- Packaging
- 100mg
- Price
- $77
- Updated
- 2021/12/16
- Product number
- CS-0061723
- Product name
- N-Methylpyrimidin-2-amine
- Packaging
- 1g
- Price
- $142
- Updated
- 2021/12/16
2-Pyrimidinamine, N-methyl- (9CI) Chemical Properties,Usage,Production
Synthesis
1722-12-9
74-89-5
931-61-3
Step 1: Synthesis of N-methylpyrimidin-2-amine To a solution of 2-chloropyrimidine (1 g, 8.7 mmol) in methanol (10 mL) was slowly added a methanolic solution of 2Methylamine (13.2 mL, 26.2 mmol) followed by potassium carbonate (2.5 g, 18 mmol). The reaction flask was sealed and the reaction was stirred at 80 °C overnight. Upon completion of the reaction, the mixture was cooled to room temperature and concentrated by rotary evaporator to remove volatile solvents. The residue was extracted by liquid-liquid partition with distilled water and dichloromethane. The organic layer was separated, dried over anhydrous sodium sulfate, filtered and concentrated to give 2-methylaminopyrimidine (290 mg, 30% yield) as a brown oil.
References
[1] Bulletin of the Chemical Society of Japan, 1998, vol. 71, # 8, p. 1973 - 1991
[2] Journal of Medicinal Chemistry, 2013, vol. 56, # 17, p. 6626 - 6637
[3] Molecules, 2004, vol. 9, # 7, p. 520 - 526
[4] Patent: WO2011/71716, 2011, A1. Location in patent: Page/Page column 99
[5] Journal of the American Chemical Society, 1954, vol. 76, p. 1065,1067
2-Pyrimidinamine, N-methyl- (9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
View Lastest Price from 2-Pyrimidinamine, N-methyl- (9CI) manufacturers
- Product
- 2-Pyrimidinamine, N-methyl- (9CI) 931-61-3
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-12-13
- Product
- 2-Pyrimidinamine, N-methyl- (9CI) 931-61-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 25kg
- Release date
- 2019-07-12