Ethyl alpha-Formyl Benzeneacetic Acid Ester Property

Melting point:

50 °C

Boiling point:

135-140 °C(Press: 10 Torr)

Density 

1.108±0.06 g/cm3(Predicted)

solubility 

Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

6.86±0.29(Predicted)

color 

White to Off-White

Dielectric constant

3.0（20℃）

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

Ethyl alpha-Formyl Benzeneacetic Acid Ester Chemical Properties,Usage,Production

Chemical Properties

Liquid. Boiling point 110-120℃/2.72-4.08kPa.

Uses

Ethyl-2-formyl-2-phenylacetate is an intermediate of Lixisheng.

Synthesis

Use ethyl phenylacetate and ethyl formate to condense under the participation of metallic sodium to generate α-(sodium methacrylate) ethyl phenylacetate, and then acidify to obtain Ethyl-2-formyl-2-phenylacetate.