2,6-Difluoroiodobenzene
- Product Name
- 2,6-Difluoroiodobenzene
- CAS No.
- 13697-89-7
- Chemical Name
- 2,6-Difluoroiodobenzene
- Synonyms
- 2-Iodo-1,3-difluorobenzene;2,6-DIFLUORO-1-IODOBENZENE;Benzene,1,3-difluoro-2-iodo-;1,3-Difluoro-2-iodobenzene>2,6-Difluoroiodobenzene ISO 9001：2015 REACH
- CBNumber
- CB11113126
- Molecular Formula
- C6H3F2I
- Formula Weight
- 239.99
- MOL File
- 13697-89-7.mol
2,6-Difluoroiodobenzene Property
- Melting point:
- 24-26℃
- Boiling point:
- 186℃
- Density
- 2.001
- Flash point:
- 69℃
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- powder to lump to clear liquid
- color
- White or Colorless to Yellow
- InChIKey
- VQMXWPLTZBKNEH-UHFFFAOYSA-N
- CAS DataBase Reference
- 13697-89-7
Safety
- Hazard Codes
- Xi
- HazardClass
- IRRITANT
- HS Code
- 2903998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- D3643
- Product name
- 1,3-Difluoro-2-iodobenzene
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $84
- Updated
- 2025/07/31
- Product number
- D446048
- Product name
- 2,6-Difluoroiodobenzene
- Packaging
- 500mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- HCH0002322
- Product name
- 2,6-DIFLUOROIODOBENZENE
- Purity
- 95.00%
- Packaging
- 25G
- Price
- $1219.68
- Updated
- 2021/12/16
- Product number
- HCH0002322
- Product name
- 2,6-DIFLUOROIODOBENZENE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $793.49
- Updated
- 2021/12/16
- Product number
- 1600-K-07
- Product name
- 2,6-Difluoroiodobenzene
- Packaging
- 100g
- Price
- $132
- Updated
- 2021/12/16
2,6-Difluoroiodobenzene Chemical Properties,Usage,Production
Synthesis
372-18-9
13697-89-7
The general procedure for the synthesis of 2,6-difluoroiodobenzene from 1,3-difluorobenzene was as follows: n-butyllithium (n-BuLi, 42 mL, 105 mmol) was slowly added to an anhydrous tetrahydrofuran (THF, 50 mL) solution of 1,3-difluorobenzene (10.0 g, 87 mmol) over a period of 10 min at -78 °C and under nitrogen protection. Subsequently, the reaction mixture was gradually warmed to room temperature and held for 5 minutes. Next, a tetrahydrofuran (THF, 200 mL) solution of iodine (26.7 g, 105 mmol) was slowly added and the reaction mixture continued to be stirred for 4 hours at room temperature. Upon completion of the reaction, the reaction was quenched with water and the organic phase was extracted with dichloromethane (CH2Cl2), followed by washing the organic layer with brine and drying with anhydrous sodium sulfate (Na2SO4). After filtration, the target product 2,6-difluoroiodobenzene (12.5 g, 74% yield) was obtained by concentration under reduced pressure. The structure of the product was confirmed by 1H NMR (CDCl3): δ 7.24-7.30 (1H, m), 6.89 (2H, dd, J = 6.6 Hz, 8.4 Hz).
References
[1] European Journal of Organic Chemistry, 2002, # 19, p. 3351 - 3358
[2] Angewandte Chemie - International Edition, 2018, vol. 57, # 1, p. 187 - 191
[3] Angew. Chem., 2018, vol. 130, p. 193 - 197,5
[4] Patent: WO2013/71865, 2013, A1. Location in patent: Page/Page column 56
[5] Patent: CN103102349, 2017, B. Location in patent: Paragraph 0493-0495
2,6-Difluoroiodobenzene Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2,6-Difluoroiodobenzene manufacturers
- Product
- 2,6-Difluoroiodobenzene 13697-89-7
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 2000
- Release date
- 2025-04-17
- Product
- 2,6-Difluoroiodobenzene 13697-89-7
- Price
- US $101.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-29
- Product
- 2,6-Difluoroiodobenzene 13697-89-7
- Price
- US $2.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2018-12-24