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3-Bromomethyl-3-oxetanemethanol

Product Name
3-Bromomethyl-3-oxetanemethanol
CAS No.
22633-44-9
Chemical Name
3-Bromomethyl-3-oxetanemethanol
Synonyms
3-BroMoMethyl-3-(hydroxyM...;3-Bromomethyl-3-oxetanemethanol;3-Oxetanemethanol, 3-(bromomethyl)-;3-Bromomethyl-3-oxetanemethanol,95%;[3-(Bromomethyl)-3-oxetanyl]methanol;3-Bromomethyl-3-hydroxymethyloxetane;[3-(BROMOMETHYL)OXETAN-3-YL]METHANOL;3-bromomethyl-3-hydroxymethyl-1-oxacyclobutane;(3-(Bromomethyl)oxetan-3-yl)methanol - [B5888];2-(Bromomethyl)-2-(hydroxymethyl)-1,3-epoxypropane
CBNumber
CB11122339
Molecular Formula
C5H9BrO2
Formula Weight
181.03
MOL File
22633-44-9.mol
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3-Bromomethyl-3-oxetanemethanol Property

Boiling point:
242℃
Density 
1.598
refractive index 
1.5130 to 1.5170
Flash point:
100°(212°F)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
clear liquid
pka
14.58±0.10(Predicted)
color 
Colorless to Light yellow
CAS DataBase Reference
22633-44-9
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
23-26-37-60
RIDADR 
UN3265
TSCA 
No
HS Code 
2932209090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
B5442
Product name
3-(Bromomethyl)-3-oxetanemethanol
Purity
>97.0%(GC)
Packaging
1g
Price
$118
Updated
2024/03/01
TRC
Product number
B697410
Product name
(3-(Bromomethyl)oxetan-3-yl)methanol
Packaging
5g
Price
$195
Updated
2021/12/16
AK Scientific
Product number
Z4449
Product name
(3-(Bromomethyl)oxetan-3-yl)methanol
Packaging
10g
Price
$196
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB142754
Product name
(3-(Bromomethyl)oxetan-3-yl)methanol
Packaging
2g
Price
$200
Updated
2021/12/16
ChemScene
Product number
CS-W019428
Product name
(3-(Bromomethyl)oxetan-3-yl)methanol
Purity
98.90%
Packaging
25g
Price
$275
Updated
2021/12/16
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3-Bromomethyl-3-oxetanemethanol Chemical Properties,Usage,Production

Synthesis

3296-90-0

22633-44-9

A. Synthesis of 3-bromomethyl-3-hydroxymethyl oxetane 2,2-Bis(bromomethyl)propane-1,3-diol (150 g, 0.573 mol) was dissolved in 650 mL of ethanol, followed by the slow addition of an ethanolic solution of sodium ethoxide (21%, 185.74 g, 0.573 mol) over 10 min. The reaction mixture was refluxed for 2 hours followed by stirring at room temperature for 16 hours. After completion of the reaction, the reaction mixture was filtered and the solvent was evaporated to give an oil containing solids. The crude product was dissolved in 200 mL of dichloromethane, filtered and the solvent was evaporated to give 98 g of crude 3-bromomethyl-3-hydroxymethoxetane. The crude product was purified by reduced pressure distillation (113°C, 3 mmHg) to give 52.95 g of pure product in 52% yield. NMR data: 1H NMR (δ, ppm): 3.75 (s, 2H), 3.88 (d, J = 4.9 Hz, 2H), 4.45 (s, 4H). 13C NMR (δ, ppm): 36.336 (t, J = 152.78 Hz), 45.0935 (s), 63.995 (t, J = 143.3 Hz), 77.216 (t, J = 152.78 Hz).

References

[1] Tetrahedron Letters, 2011, vol. 52, # 5, p. 565 - 567
[2] Patent: US5489700, 1996, A
[3] DRP/DRBP Org.Chem.,
[4] Journal of Organic Chemistry, 1956, vol. 21, p. 997
[5] Mededelingen van de Koninklijke Vlaamse Academie voor Wetenschappen, Letteren en Schone Kunsten van Belgie, Klasse der Wetenschappen, 1954, vol. 16, # 8, p. 3,10

3-Bromomethyl-3-oxetanemethanol Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Bromomethyl-3-oxetanemethanol Suppliers

J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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86-10-82849933
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jkinfo@jkchemical.com
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China
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Alfa Aesar
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400-6106006
Fax
021-67582001/03/05
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China
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China
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Adamas Reagent, Ltd.
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400-6009262 16621234537
Fax
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China
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Shanghai Longsheng chemical Co.,Ltd.
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Shanghai Hanhong Scientific Co.,Ltd.
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Tongchuang Pharma(Suzhou). Co., Ltd.
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Heterochem
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China
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Tianjin Derchemist Science & Technology Co., Ltd.
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22-58627059 13920586291
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022-58620305
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China
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3829
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Chengdu Forest Science and Technology Development Co., Ltd.
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18030648795
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028-61777050
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sales@cdforestchem.com
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China
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1998
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View Lastest Price from 3-Bromomethyl-3-oxetanemethanol manufacturers

Career Henan Chemical Co
Product
3-Bromomethyl-3-oxetanemethanol 22633-44-9
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2019-12-26

22633-44-9, 3-Bromomethyl-3-oxetanemethanolRelated Search:


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  • [3-(Bromomethyl)-3-oxetanyl]methanol
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  • [3-(Bromomethyl)oxetan-3-yl]methanol, 2-(Bromomethyl)-2-(hydroxymethyl)-1,3-epoxypropane
  • 3-Oxetanemethanol, 3-(bromomethyl)-
  • 3-bromomethyl-3-hydroxymethyl-1-oxacyclobutane
  • 3-Bromomethyl-3-oxetanemethanol,95%
  • 2-(Bromomethyl)-2-(hydroxymethyl)-1,3-epoxypropane
  • (3-(Bromomethyl)oxetan-3-yl)methanol - [B5888]
  • 22633-44-9
  • Methyl Halides
  • Ring Systems
  • Methyl Halides