ChemicalBook > CAS DataBase List > 2-BENZIMIDAZOLEPROPIONIC ACID

2-BENZIMIDAZOLEPROPIONIC ACID

Product Name: 2-BENZIMIDAZOLEPROPIONIC ACID
CAS No.: 23249-97-0
Chemical Name: 2-BENZIMIDAZOLEPROPIONIC ACID
Synonyms: 3-(1H-;Propazol;propazole;procodazol;procodazole;AKOS AUF2065;Procodazole [INN];IFLAB-BB F0852-0156;Procodazol [INN-Spanish];Procodazolum [INN-Latin]
CBNumber: CB1113611
Molecular Formula: C10H10N2O2
Formula Weight: 190.2
MOL File: 23249-97-0.mol

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2-BENZIMIDAZOLEPROPIONIC ACID Property

Melting point:: 229-231 °C (dec.)(lit.)
Boiling point:: 497.9±28.0 °C(Predicted)
Density: 1.367±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : ≥ 30 mg/mL (157.73 mM)
form: Solid
pka: 3.98±0.10(Predicted)
color: White to off-white
Merck: 13,7851
InChI: InChI=1S/C10H10N2O2/c13-10(14)6-5-9-11-7-3-1-2-4-8(7)12-9/h1-4H,5-6H2,(H,11,12)(H,13,14)
InChIKey: XYWJNTOURDMTPI-UHFFFAOYSA-N
SMILES: C1(CCC(O)=O)NC2=CC=CC=C2N=1
CAS DataBase Reference: 23249-97-0(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 20/21/22-36/37/38
Safety Statements: 26-37/39
WGK Germany: 3
RTECS: UE7480000
HazardClass: IRRITANT
HS Code: 29332990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 361933
Product name: 2-Benzimidazolepropionic acid
Purity: 97%
Packaging: 1g
Price: $45
Updated: 2023/06/20

Sigma-Aldrich

Product number: 361933
Product name: 2-Benzimidazolepropionic acid
Purity: 97%
Packaging: 5g
Price: $89.1
Updated: 2023/06/20

TRC

Product number: H999825
Product name: 3-(1H-Benzimidazol-2-yl)propanoicAcid
Packaging: 100mg
Price: $75
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H58-1-300
Product name: 2-Benzimidazolepropionic acid
Packaging: 1g
Price: $60
Updated: 2021/12/16

ChemScene

Product number: CS-4578
Product name: Procodazole
Purity: 98.95%
Packaging: 500mg
Price: $60
Updated: 2021/12/16

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2-BENZIMIDAZOLEPROPIONIC ACID Chemical Properties,Usage,Production

Uses

immune stimulant

Uses

2-Benzimidazolepropionic acid is suitable reagent for use in the method of generation of monoclonal antibodies against very small drug hapten, 5-benzimidazolecarboxylic acid by in vivo immunisation method and an in vitro immunisation procedure. It may be used in the synthesis of cytidine derivatives.

Definition

ChEBI: Procodazole is a member of benzimidazoles.

General Description

2-Benzimidazolepropionic acid is a 2-(4-thiazolyl)benzimidazole analog. 2-Benzimidazolepropionic acid is a 2-substituted benzimidazole ligand and its dissociation constant has been evaluated. 2-Benzimidazolepropionic acid is reported to possess active antimarial activity.

in vivo

Procodazole (50 mg per dog, p.o., once daily for 28 days) can significantly reduce the parasite burden in Beagles infected with Toxocara canis and enhance their resistance to Toxocara canisinfection^[1].

Animal Model:	Three-month-old Beagle puppies infected with 3000 embryonated Toxocara canis eggs^[2]
Dosage:	50 mg per dog
Administration:	Oral gavage (p.o.), once daily for 28 days
Result:	Reduced the number of worms significantly in the treated group compared to the untreated group, with a 63.8% reduction in worm burden.

IC 50

CA Ⅸ: 8.35 μM (IC₅₀)

2-BENZIMIDAZOLEPROPIONIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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2-BENZIMIDAZOLEPROPIONIC ACID Suppliers

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View Lastest Price from 2-BENZIMIDAZOLEPROPIONIC ACID manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: 2-BENZIMIDAZOLEPROPIONIC ACID 23249-97-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

Career Henan Chemical Co

Product: 2-BENZIMIDAZOLEPROPIONIC ACID 23249-97-0
Price: US $6.60/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 1kg -1000kg
Release date: 2020-01-02

23249-97-0, 2-BENZIMIDAZOLEPROPIONIC ACIDRelated Search:

2-BENZIMIDAZOLEPROPIONIC ACID methyl 1-methyl-1H-indole-2-carboxylate 1-Methylindole-2-carboxylic acid TERT-BUTYL 1-METHYL-4-NITRO-1H-PYRROLE-2-CARBOXYLATE METHYL 1-METHYLPYRROLE-2-CARBOXYLATE 4-(2,4-DICHLOROBENZOYL)-1-METHYL-1H-PYRROLE-2-CARBOXYLIC ACID ETHYL 4-CHLORO-5-METHYL-7-PHENYL-7H-PYRROLO[2,3-D]PYRIMIDINE-6-CARBOXYLATE METHYL 4-(2,4-DICHLOROBENZOYL)-1-METHYL-1H-PYRROLE-2-CARBOXYLATE 4-ACETYL-1-METHYL-1H-PYRROLE-2-CARBOXYLIC ACID ETHYL 1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-1H-PYRROLE-2-CARBOXYLATE ETHYL 1-(4-CHLOROBENZYL)-3-(1H-PYRROL-1-YL)-1H-INDOLE-2-CARBOXYLATE 1-PHENYL-1H-INDOLE-2-CARBOXYLIC ACID METHYL 4-ACETYL-1-METHYL-1H-PYRROLE-2-CARBOXYLATE SPECS AE-508/36399029 ETHYL 1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-3-(1H-PYRROL-1-YL)-1H-INDOLE-2-CARBOXYLATE 1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-1H-PYRROLE-2-CARBOXYLIC ACID RARECHEM AL BF 0409 ETHYL 1-(2,4-DICHLOROBENZYL)-3-((2,4-DICHLOROBENZYL)[3-(TRIFLUOROMETHYL)BENZOYL]AMINO)-1H-INDOLE-2-CARBOXYLATE

2-(2-carboxyethyl)benzimidazole

(2-benzimidazolyl)propionicacid

1h-benzimidazole-2-propanoicacid

2-(2-benzimidazolyl)-propionicaci

1H-Benzimidazole-2-propionic acid

3-(1H-Benzoimidazole-2-yl)propanoic acid

3-(1H-Benzoimidazole-2-yl)propionic acid

1H-BenziMidazol-2-propionic acid

3-(1H-

3-(1H-benzimidazol-2-yl)propionic acid

3-(1H-benzimidazol-3-ium-2-yl)propanoate

3-(1H-benzo[d]imidazol-2-yl)propanoic acid

Procodazol [INN-Spanish]

Procodazole [INN]

Procodazolum [INN-Latin]

Propazol

Propionic acid, 2-(2-benzimidazolyl)-

beta-(2-benzimidazole)propionicacid

beta-(2-benzimidazolyl)propionicacid

procodazol

procodazole

2-BENZIMIDAZOLEPROPIONIC ACID 97%

1H-Benzimidazole-2-propanoicacid(9CI)

(BENZIMIDAZOLYL)PROPIONIC ACID

IFLAB-BB F0852-0156

AKOS AUF2065

3-(1H-1,3-BENZIMIDAZOL-2-YL)PROPANOIC ACID

3-(1H-BENZIMIDAZOL-2-YL)PROPANOIC ACID

3-(1H-BENZOIMIDAZOL-2-YL)-PROPIONIC ACID

2-BENZIMIDAZOLEPROPIONIC ACID

propazole

inhibit,Inhibitor,Bacterial,Procodazole

Procodazole, 10 mM in DMSO

3-(2-Benzimidazolyl)propanoic Acid

23249-97-0

Heterocyclic Building Blocks

Benzimidazoles

Building Blocks

Benzimidazoles

Building Blocks

Heterocyclic Building Blocks

BENZIMIDAZOLE

Building Blocks

Chemical Synthesis

Heterocyclic Building Blocks

ESTIMULOCEL