1-Methylindole-2-carboxylic acid

Product Name: 1-Methylindole-2-carboxylic acid
CAS No.: 16136-58-6
Chemical Name: 1-Methylindole-2-carboxylic acid
Synonyms: 1-Me-ICA;NSC 68357;AKOS JY2082906;RARECHEM AL BE 0864;2-Carboxy-1-methyl-1H-indole;1-methyl-2-indolecarboxylicacid;1-METHYLINDOLE-2-CARBOXYLIC ACID;N-METHYL-2-INDOLECARBOXYLIC ACID;1-Methyl-2-indolecarboxylic acid;N-Methylindole-2-carboxylic acid
CBNumber: CB2398286
Molecular Formula: C10H9NO2
Formula Weight: 175.18
MOL File: 16136-58-6.mol

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1-Methylindole-2-carboxylic acid Property

Melting point:: 212-213 °C (dec.) (lit.)
Boiling point:: 389.0±15.0 °C(Predicted)
Density: 1.24±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: Crystalline Powder
pka: 4.19±0.30(Predicted)
color: Beige
CAS DataBase Reference: 16136-58-6(CAS DataBase Reference)
NIST Chemistry Reference: 1-Methylindole-2-carboxylic acid(16136-58-6)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 22-36/37/38
Safety Statements: 26
WGK Germany: 3
RTECS: NL6012400
HazardClass: IRRITANT
HS Code: 29339980

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 134155
Product name: 1-Methylindole-2-carboxylic acid
Purity: 98%
Packaging: 1g
Price: $82.5
Updated: 2023/06/20

Sigma-Aldrich

Product number: 134155
Product name: 1-Methylindole-2-carboxylic acid
Purity: 98%
Packaging: 5g
Price: $250
Updated: 2023/06/20

TCI Chemical

Product number: M1519
Product name: 1-Methylindole-2-carboxylic Acid
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $49
Updated: 2024/03/01

TCI Chemical

Product number: M1519
Product name: 1-Methylindole-2-carboxylic Acid
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $141
Updated: 2024/03/01

TRC

Product number: M313615
Product name: 1-Methylindole-2-carboxylic acid
Packaging: 1g
Price: $75
Updated: 2021/12/16

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1-Methylindole-2-carboxylic acid Chemical Properties,Usage,Production

Chemical Properties

Beige crystalline powder

Uses

• ;Reactant for preparation of keto-indoles as novel indoleamine 2,3-dioxygenase (IDO) inhibitors1• ;Reactant for synthesis of fenbufen and ethacrynic acid derivatives as potential antitumor agents via amide coupling reactions2• ;Reactant for diastereoselective synthesis of vinylated heterocycles via ruthenium-catalyzed oxidative vinylation with alkenes3• ;Reactant for synthesis of 2,3-dihalo indoles via hypervalent iodine mediated decarboxylative halogenation4• ;Reactant for preparation of α-ketoamides as cathepsin S inhibitors with potential applications ag

Uses

Reactant for preparation of keto-indoles as novel indoleamine 2,3-dioxygenase (IDO) inhibitors
Reactant for synthesis of fenbufen and ethacrynic acid derivatives as potential antitumor agents via amide coupling reactions
Reactant for diastereoselective synthesis of vinylated heterocycles via ruthenium-catalyzed oxidative vinylation with alkenes
Reactant for synthesis of 2,3-dihalo indoles via hypervalent iodine mediated decarboxylative halogenation
Reactant for preparation of α-ketoamides as cathepsin S inhibitors with potential applications against tumor invasion and angiogenesis
Reactant for preparation of anthranilic acid mimics as bacterial translation inhibitors

General Description

1-Methylindole-2-carboxylic acid reacts with thionyl chloride to yield sulfinyl chlorides.

1-Methylindole-2-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Methylindole-2-carboxylic acid Suppliers

Americas 1 China 114 Europe 3 Finland 1 France 1 Germany 6 India 9 Japan 1 Slovakia 1 Switzerland 5 The Netherlands 2 Ukraine 2 United Kingdom 11 United States 30 Global 187

J & K SCIENTIFIC LTD.

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3B Pharmachem (Wuhan) International Co.,Ltd.

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Energy Chemical

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Shanghai Hanhong Scientific Co.,Ltd.

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Shandong Xiya Chemical Co., Ltd

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Syntechem Co.,Ltd

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Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: +8618575662672 18575662672
Fax: 021 51613951
Email: mzeng@3wpharm.com
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ProdList: 9747
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View Lastest Price from 1-Methylindole-2-carboxylic acid manufacturers

Career Henan Chemical Co

Product: 1-Methylindole-2-carboxylic acid 16136-58-6
Price: US $6.60/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 1kg -1000kg
Release date: 2020-01-02

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1-Me-ICA

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16136-58-6

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