ChemicalBook > CAS DataBase List > Indole-2-carboxylic acid

Indole-2-carboxylic acid

Product Name
Indole-2-carboxylic acid
CAS No.
1477-50-5
Chemical Name
Indole-2-carboxylic acid
Synonyms
1H-INDOLE-2-CARBOXYLIC ACID;2-INDOLECARBOXYLIC ACID;NSC 16598;e-2-carboxyL;AKOS JY2082713;2-CARBOXYINDOLE;Indol-2-carbonsure;Indole-2-carboxylic;2-Carboxy-1H-indole;TIMTEC-BB SBB003953
CBNumber
CB7728231
Molecular Formula
C9H7NO2
Formula Weight
161.16
MOL File
1477-50-5.mol
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Indole-2-carboxylic acid Property

Melting point:
202-206 °C(lit.)
Boiling point:
287.44°C (rough estimate)
Density 
1.2480 (rough estimate)
refractive index 
1.5050 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Soluble in clear yellow solution 5% in ethanol, dimethyl sulfoxide and methanol.
pka
4.44±0.30(Predicted)
form 
Crystalline Powder or Crystals
color 
Off-white to yellow to brown
BRN 
124132
CAS DataBase Reference
1477-50-5(CAS DataBase Reference)
NIST Chemistry Reference
Indole-2-carboxylic acid(1477-50-5)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
36/37/38-21/22
Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
NK7882812
HazardClass 
IRRITANT
HS Code 
29339990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H301Toxic if swalloed

H311Toxic in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
I5109
Product name
Indole-2-carboxylic acid
Purity
98%
Packaging
5g
Price
$112
Updated
2024/03/01
Sigma-Aldrich
Product number
I5109
Product name
Indole-2-carboxylic acid
Purity
98%
Packaging
10g
Price
$113
Updated
2024/03/01
TCI Chemical
Product number
I0332
Product name
Indole-2-carboxylic Acid
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$18
Updated
2024/03/01
TCI Chemical
Product number
I0332
Product name
Indole-2-carboxylic Acid
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$37
Updated
2024/03/01
Alfa Aesar
Product number
A18690
Product name
Indole-2-carboxylic acid, 98+%
Packaging
10g
Price
$52.8
Updated
2022/04/27
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Indole-2-carboxylic acid Chemical Properties,Usage,Production

Chemical Properties

Yellow Crystalline Powder

Uses

• ;Reactant for total synthesis of (±)-dibromophakellin and analogs1• ;Reactant for synthesis of the pyrrolizidine alkaloid (±)-trachelanthamidine2• ;Reactant for stereoselective preparation of renieramycin G analogs3• ;Reactant for preparation of spirooxoindolepyrrolidines via reduction of indole-2-carboxylic acid followed by oxidation, condensation, reduction, amidation and Kharasch radical cyclization4• ;Reactant for Pd-catalyzed cyclization5• ;Reactant for preparation of N,N′-(pentane)diylbis[indolecarboxamide] and N,N′-[phenylenebis(

Uses

Reactant for total synthesis of (±)-dibromophakellin and analogs, synthesis of the pyrrolizidine alkaloid (±)-trachelanthamidine, stereo selective preparation of renieramycin G analogs, preparation of spirooxoindolepyrrolidines via reduction of indole-2-carboxylic acid followed by oxidation, condensation, reduction, amidation and Kharasch radical cyclization, Pd-catalyzed cyclization and N,N?-(pentane)diylbis[indolecarboxamide] and N,N?-[phenylenebis(methylene)]bis[indolecarboxamide] derivatives.

Definition

ChEBI: Indole-2-carboxylic acid is an indolyl carboxylic acid.

Synthesis Reference(s)

Tetrahedron Letters, 33, p. 7961, 1992 DOI: 10.1016/S0040-4039(00)74789-7

Indole-2-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Indole-2-carboxylic acid Suppliers

Shanghai Harvest Chemical Industrial Co., Ltd.
Tel
21-31038972 15721252604
Fax
+86-21-51385350
Email
ammyzuo@harvest-chem.com
Country
China
ProdList
2540
Advantage
64
Hunan Daolin Biotechnology Co. , Ltd.
Tel
18974846212
Email
1876969603@qq.com
Country
China
ProdList
57
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
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76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
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Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
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81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
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61
Beijing Mediking Biopharm Co., Ltd
Tel
010-81769521,89753524,81760121 15901403431
Fax
+86-10-81769652
Email
sales01@mediking.cn
Country
China
ProdList
704
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68
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
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View Lastest Price from Indole-2-carboxylic acid manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Indole-2-carboxylic acid 1477-50-5
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-21
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Indole-2-carboxylic acid 1477-50-5
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
10 ton
Release date
2021-07-27
Hebei Chuanghai Biotechnology Co,.LTD
Product
Indole-2-carboxylic acid 1477-50-5
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-20

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