Methyl indole-3-carboxylate

Product Name: Methyl indole-3-carboxylate
CAS No.: 942-24-5
Chemical Name: Methyl indole-3-carboxylate
Synonyms: METHYL 1H-INDOLE-3-CARBOXYLATE;3-Methoxycarbonylindole;methyl indoline-3-carboxylate;INDOLE-3-CARBOXYLIC ACID METHYL ESTER;1H-INDOLE-3-CARBOXYLIC ACID METHYL ESTER;RARECHEM AH BS 0112;3-Carbomethoxyindole;Oxiracetam Impurity 38;3-indole,Methyl forMate;Tropisetron Impurity 23
CBNumber: CB9385281
Molecular Formula: C10H9NO2
Formula Weight: 175.18
MOL File: 942-24-5.mol

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Methyl indole-3-carboxylate Property

Melting point:: 149-152 °C (lit.)
Boiling point:: 306.47°C (rough estimate)
Density: 1.1999 (rough estimate)
refractive index: 1.5060 (estimate)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 15.42±0.30(Predicted)
color: Light Pink
Water Solubility: Slightly soluble methanol and dimethyl sulfoxide. Insoluble in water.
BRN: 142023
CAS DataBase Reference: 942-24-5(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-37/39
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H402Harmful to aquatic life

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 395307
Product name: Methyl indole-3-carboxylate
Purity: 99%
Packaging: 25g
Price: $78.5
Updated: 2023/06/20

TCI Chemical

Product number: I0491
Product name: Methyl Indole-3-carboxylate
Purity: >98.0%(GC)
Packaging: 25g
Price: $35
Updated: 2024/03/01

TCI Chemical

Product number: I0491
Product name: Methyl Indole-3-carboxylate
Purity: >98.0%(GC)
Packaging: 500g
Price: $377
Updated: 2024/03/01

Alfa Aesar

Product number: L14516
Product name: Methyl indole-3-carboxylate, 99%
Packaging: 25g
Price: $45.65
Updated: 2024/03/01

Alfa Aesar

Product number: L14516
Product name: Methyl indole-3-carboxylate, 99%
Packaging: 100g
Price: $150.65
Updated: 2024/03/01

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Methyl indole-3-carboxylate Chemical Properties,Usage,Production

Chemical Properties

light brown amorphous powder

Uses

Methyl indole-3-carboxylate is a reagent in the preaparation of oncrasin-1 derivatives which is a novel inhibitor of the C-terminal domain of RNA polymerase II.

Uses

Reactant for preparation of:

Nitric oxide synthase (nNOS) inhibitorS
Protein kinase c alpha (PKCα) inhibitors
Inhibitors of the C-terminal domain of RNA polymerase II as antitumor agents
Kinase insert domain receptor (KDR) inhibitors
Organocatalysts for the anti-Mannich reaction
Very late antigen-4 (VLA-4) antagonists
Inhibitors of Human 5-Lipoxygenase
Serotonin 5-HT4 receptor antagonists
Hyaluronidase inhibitors

Reactant for:

Enantioselective Meerwein-Eschenmoser Claisen rearrangement reactions?

Definition

ChEBI: Methyl indole-3-carboxylate is the methyl ester of indole-3-carboxylic acid. It has a role as a metabolite. It is a member of indoles and a methyl ester. It is functionally related to an indole-3-carboxylic acid.

General Description

Methyl indole-3-carboxylate (3-Methoxycarbonylindole, 3-Carbomethoxyindole, Methyl indolyl-3-carboxylate) has been extracted from the marine Streptomyces sp. 060524. Its crystal structure indicates the presence of inter-molecular N-H…O hydrogen bond. It is also obtained during the isolation of sorazinones A and B from Sorangium cellulosum strain Soce895. It undergoes regioselective dibromination with bromine in acetic acid to afford methyl 5,6-dibromoindole-3-carboxylate.

Methyl indole-3-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyl indole-3-carboxylate Suppliers

Americas 1 Austria 1 Belgium 3 China 212 Czech Republic 1 Europe 3 Germany 12 India 7 Japan 3 Slovakia 1 Switzerland 4 United Kingdom 17 United States 39 Global 304

Sichuan BioCrick Biotech Co., Ltd

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Alfa Aesar

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Energy Chemical

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Capot Chemical Co., Ltd

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JinYan Chemicals(ShangHai) Co.,Ltd.

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View Lastest Price from Methyl indole-3-carboxylate manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: Methyl indole-3-carboxylate 942-24-5
Price: US $150.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5ton
Release date: 2024-04-22

Hebei Yanxi Chemical Co., Ltd.

Product: Methyl indole-3-carboxylate 942-24-5
Price: US $30.00-10.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 10 tons
Release date: 2023-10-23

Hebei Mojin Biotechnology Co., Ltd

Product: Methyl indole-3-carboxylate 942-24-5
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-10-09

942-24-5, Methyl indole-3-carboxylateRelated Search:

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METHYL-(3-INDOLCARBOXYLATE) FOR SYNTHESI

INDOLE-3-CARBOXYLIC ACID METHYL ESTER(I3CAMe)

Indole -3-Methyl forMate

3-indole,Methyl forMate

Indole-3-carboxylicacidmethylester,99%

3-Carbomethoxyindole

3-Methoxycarbonylindole

Methyl indole-3-carboxylate 99%

INDOLE-3-CARBOXYLIC ACID METHYL ESTER

METHYL INDOLE-3-CARBOXYLATE

METHYL 1H-INDOLE-3-CARBOXYLATE

METHYL-(3-INDOLCARBOXYLATE)

3-Indolecarboxylic acid methyl ester

1H-INDOLE-3-CARBOXYLIC ACID METHYL ESTER

RARECHEM AH BS 0112

methyl indoline-3-carboxylate

Methylindole-3-Carboxylate99%

MethylIndole-3-carboxylate&gt

TIANFU 942-24-5 Methyl indole-3-carboxylate

Tropisetron Impurity 23

Oxiracetam Impurity 38

942-24-5

42-24-5

842-24-5

Heterocyclic Building Blocks

Building Blocks

Indoles

Simple Indoles

Heterocycle-Indole series

Indoles

Simple Indoles

Building Blocks

Heterocyclic Building Blocks

Indoles and derivatives

Heterocycles series

IndoleDerivative

Indole