Indole-7-boronic acid pinacol ester

Product Name: Indole-7-boronic acid pinacol ester
CAS No.: 642494-37-9
Chemical Name: Indole-7-boronic acid pinacol ester
Synonyms: INDOLE-7-BORONIC ACID PINACOL ESTER;1H-Indole-7-boronic acid, pinacol ester;1H-INDOL-7-YLBORONIC ACID PINACOL ESTER;REF DUPL: Indole-7-boronic acid pinacol ester;Indole-7-boronic acid pinacol ester - [I12588];7-(tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-indole;4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3H-indole;7-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-INDOLE;1H-Indole, 7-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-;3-hydroxy-2,3-dimethylbutan-2-yl hydrogen 1H-indol-7-ylboronate
CBNumber: CB7839311
Molecular Formula: C14H18BNO2
Formula Weight: 243.11
MOL File: 642494-37-9.mol

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Indole-7-boronic acid pinacol ester Property

Melting point:: 94-96 °C
Boiling point:: 396.0±15.0 °C(Predicted)
Density: 1.11±0.1 g/cm3(Predicted)
storage temp.: Inert atmosphere,2-8°C
form: crystalline powder
pka: 17.01±0.30(Predicted)
color: White

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Safety

Hazard Codes: Xi
HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC

Product number: I577788
Product name: Indole-7-boronicacid,pinacolester
Packaging: 1g
Price: $175
Updated: 2021/12/16

Apolloscientific

Product number: OR59787
Product name: 1H-Indole-7-boronicacid,pinacolester
Purity: 97%
Packaging: 1g
Price: $83
Updated: 2021/12/16

SynQuest Laboratories

Product number: 8H60-1-W1
Product name: 1H-Indole-7-boronic acid, pinacol ester
Purity: 97%
Packaging: 1g
Price: $108
Updated: 2021/12/16

Apolloscientific

Product number: OR59787
Product name: 1H-Indole-7-boronicacid,pinacolester
Purity: 97%
Packaging: 5g
Price: $392
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: ING0005369
Product name: INDOLE-7-BORONIC ACID PINACOL ESTER
Purity: 95.00%
Packaging: 250MG
Price: $475
Updated: 2021/12/16

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Indole-7-boronic acid pinacol ester Chemical Properties,Usage,Production

Uses

Indole-7-boronic acid, pinacol ester

Synthesis

51417-51-7

73183-34-3

642494-37-9

The general procedure for the synthesis of 7-bromoindole and pinacol ester of bis(pinacolato) borate from 7-bromoindole and pinacol ester of bis(pinacolato) borate was as follows: 7-bromoindole (20 g, 0.102 mol) was dissolved in a 1 L single-necked flask containing DMSO (100 mL), and bis(pinacolato)diboron (39 g, 0.153 mol), [1,1'-bis(diphenylphosphinato)ferrocene]dichloro palladium (Pd(dppf)Cl2, 4 g, 0.005 mol) and potassium acetate (15 g, 0.153 mol). The reaction system was heated to 85 °C and the reaction was stirred for 2 hours. After completion of the reaction, the reaction was quenched by the addition of water. The mixture was extracted three times with ethyl acetate, the organic phases were combined and dried over anhydrous sodium sulfate. After concentration under reduced pressure, the product was purified by column chromatography to afford the target product 7-indoleboronic acid pinacol ester (25 g, 0.103 mol). The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3) and mass spectrometry (ESI): 1H NMR (400 MHz, CDCl3) δ 9.29 (s, 1H), 7.82 (d, J = 7.9 Hz, 1H), 7.70 (d, J = 7.0 Hz, 1H), 7.32-7.29 (m, 1H), 7.21- 7.14 (m, 1H), 6.62-6.57 (m, 1H), 1.44 (s, 12H); MS (ESI) m/z: [M + H]+ 244.1.

References

[1] Synlett, 2003, # 8, p. 1204 - 1206
[2] Advanced Synthesis and Catalysis, 2017, vol. 359, # 19, p. 3421 - 3427
[3] Journal of the American Chemical Society, 2017, vol. 139, # 24, p. 8267 - 8276
[4] European Journal of Organic Chemistry, 2016, vol. 2016, # 27, p. 4621 - 4628
[5] Patent: JP2015/528445, 2015, A. Location in patent: Paragraph 0047; 0065

Indole-7-boronic acid pinacol ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Indole-7-boronic acid pinacol ester Suppliers

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View Lastest Price from Indole-7-boronic acid pinacol ester manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: Indole-7-boronic acid pinacol ester 642494-37-9
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-11

Zhuozhou Wenxi import and Export Co., Ltd

Product: Indole-7-boronic acid pinacol ester 642494-37-9
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

Career Henan Chemical Co

Product: Indole-7-boronic acid pinacol ester 642494-37-9
Price: US $3500.00-3200.00/KG
Min. Order: 1G
Purity: 98%
Supply Ability: 1000KG
Release date: 2018-08-03

642494-37-9, Indole-7-boronic acid pinacol esterRelated Search:

Indole-3-butyric acid Indometacin Indole-3-acetic acid Methyl acrylate Tris(trimethylsilyl)phosphate BUTYL OLEATE Bis(pinacolato)diboron INDOLE-6-BORONIC ACID PINACOL ESTER Indole-4-boronic acid pinacol ester Ethyl indole-3-carboxylate Indole-3-carboxaldehyde Indole-5-carboxylic acid Indole-4-carboxylic acid Methyl 1H-indole-7-carboxylate Methyl indole-4-carboxylate Indole-3-carboxylic acid Indoline Methyl indole-6-carboxylate

1H-INDOL-7-YLBORONIC ACID PINACOL ESTER

7-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-INDOLE

7-(tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-indole

1H-Indole, 7-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-

7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole, 2-(1H-Indol-7-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3H-indole

3-hydroxy-2,3-dimethylbutan-2-yl hydrogen 1H-indol-7-ylboronate

1H-Indole-7-boronic acid, pinacol ester

INDOLE-7-BORONIC ACID PINACOL ESTER

REF DUPL: Indole-7-boronic acid pinacol ester

7-4,4,5,5-Tetramethyl)-1,3,2-dioxaborolan-2-yl)-1H-indole, CAS 642494-37-9

Indole-7-boronic acid pinacol ester - [I12588]

642494-37-9

Boronic ester

Indole

Organoborons