ChemicalBook > CAS DataBase List > Indole-7-boronic acid pinacol ester

Indole-7-boronic acid pinacol ester

Product Name
Indole-7-boronic acid pinacol ester
CAS No.
642494-37-9
Chemical Name
Indole-7-boronic acid pinacol ester
Synonyms
INDOLE-7-BORONIC ACID PINACOL ESTER;1H-Indole-7-boronic acid, pinacol ester;1H-INDOL-7-YLBORONIC ACID PINACOL ESTER;REF DUPL: Indole-7-boronic acid pinacol ester;Indole-7-boronic acid pinacol ester - [I12588];7-(tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-indole;4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3H-indole;7-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-INDOLE;1H-Indole, 7-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-;3-hydroxy-2,3-dimethylbutan-2-yl hydrogen 1H-indol-7-ylboronate
CBNumber
CB7839311
Molecular Formula
C14H18BNO2
Formula Weight
243.11
MOL File
642494-37-9.mol
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Indole-7-boronic acid pinacol ester Property

Melting point:
94-96 °C
Boiling point:
396.0±15.0 °C(Predicted)
Density 
1.11±0.1 g/cm3(Predicted)
storage temp. 
Inert atmosphere,2-8°C
form 
crystalline powder
pka
17.01±0.30(Predicted)
color 
White
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Safety

Hazard Codes 
Xi
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC
Product number
I577788
Product name
Indole-7-boronicacid,pinacolester
Packaging
1g
Price
$175
Updated
2021/12/16
Apolloscientific
Product number
OR59787
Product name
1H-Indole-7-boronicacid,pinacolester
Purity
97%
Packaging
1g
Price
$83
Updated
2021/12/16
SynQuest Laboratories
Product number
8H60-1-W1
Product name
1H-Indole-7-boronic acid, pinacol ester
Purity
97%
Packaging
1g
Price
$108
Updated
2021/12/16
Apolloscientific
Product number
OR59787
Product name
1H-Indole-7-boronicacid,pinacolester
Purity
97%
Packaging
5g
Price
$392
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
ING0005369
Product name
INDOLE-7-BORONIC ACID PINACOL ESTER
Purity
95.00%
Packaging
250MG
Price
$475
Updated
2021/12/16
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Indole-7-boronic acid pinacol ester Chemical Properties,Usage,Production

Uses

Indole-7-boronic acid, pinacol ester

Synthesis

51417-51-7

73183-34-3

642494-37-9

The general procedure for the synthesis of 7-bromoindole and pinacol ester of bis(pinacolato) borate from 7-bromoindole and pinacol ester of bis(pinacolato) borate was as follows: 7-bromoindole (20 g, 0.102 mol) was dissolved in a 1 L single-necked flask containing DMSO (100 mL), and bis(pinacolato)diboron (39 g, 0.153 mol), [1,1'-bis(diphenylphosphinato)ferrocene]dichloro palladium (Pd(dppf)Cl2, 4 g, 0.005 mol) and potassium acetate (15 g, 0.153 mol). The reaction system was heated to 85 °C and the reaction was stirred for 2 hours. After completion of the reaction, the reaction was quenched by the addition of water. The mixture was extracted three times with ethyl acetate, the organic phases were combined and dried over anhydrous sodium sulfate. After concentration under reduced pressure, the product was purified by column chromatography to afford the target product 7-indoleboronic acid pinacol ester (25 g, 0.103 mol). The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3) and mass spectrometry (ESI): 1H NMR (400 MHz, CDCl3) δ 9.29 (s, 1H), 7.82 (d, J = 7.9 Hz, 1H), 7.70 (d, J = 7.0 Hz, 1H), 7.32-7.29 (m, 1H), 7.21- 7.14 (m, 1H), 6.62-6.57 (m, 1H), 1.44 (s, 12H); MS (ESI) m/z: [M + H]+ 244.1.

References

[1] Synlett, 2003, # 8, p. 1204 - 1206
[2] Advanced Synthesis and Catalysis, 2017, vol. 359, # 19, p. 3421 - 3427
[3] Journal of the American Chemical Society, 2017, vol. 139, # 24, p. 8267 - 8276
[4] European Journal of Organic Chemistry, 2016, vol. 2016, # 27, p. 4621 - 4628
[5] Patent: JP2015/528445, 2015, A. Location in patent: Paragraph 0047; 0065

Indole-7-boronic acid pinacol ester Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Indole-7-boronic acid pinacol ester manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
Indole-7-boronic acid pinacol ester 642494-37-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-11
Zhuozhou Wenxi import and Export Co., Ltd
Product
Indole-7-boronic acid pinacol ester 642494-37-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09
Career Henan Chemical Co
Product
Indole-7-boronic acid pinacol ester 642494-37-9
Price
US $3500.00-3200.00/KG
Min. Order
1G
Purity
98%
Supply Ability
1000KG
Release date
2018-08-03

642494-37-9, Indole-7-boronic acid pinacol esterRelated Search:

Indole-3-butyric acid Indometacin Indole-3-acetic acid Methyl acrylate Tris(trimethylsilyl)phosphate BUTYL OLEATE Bis(pinacolato)diboron INDOLE-6-BORONIC ACID PINACOL ESTER Indole-4-boronic acid pinacol ester Ethyl indole-3-carboxylate Indole-3-carboxaldehyde Indole-5-carboxylic acid Indole-4-carboxylic acid Methyl 1H-indole-7-carboxylate Methyl indole-4-carboxylate Indole-3-carboxylic acid Indoline Methyl indole-6-carboxylate

  • 1H-INDOL-7-YLBORONIC ACID PINACOL ESTER
  • 7-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-INDOLE
  • 7-(tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-indole
  • 1H-Indole, 7-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-
  • 7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole, 2-(1H-Indol-7-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
  • 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3H-indole
  • 3-hydroxy-2,3-dimethylbutan-2-yl hydrogen 1H-indol-7-ylboronate
  • 1H-Indole-7-boronic acid, pinacol ester
  • INDOLE-7-BORONIC ACID PINACOL ESTER
  • REF DUPL: Indole-7-boronic acid pinacol ester
  • 7-4,4,5,5-Tetramethyl)-1,3,2-dioxaborolan-2-yl)-1H-indole, CAS 642494-37-9
  • Indole-7-boronic acid pinacol ester - [I12588]
  • 642494-37-9
  • Boronic ester
  • Indole
  • Organoborons