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1-Methylindole-2-carboxylic acid

Product Name
1-Methylindole-2-carboxylic acid
CAS No.
16136-58-6
Chemical Name
1-Methylindole-2-carboxylic acid
Synonyms
1-Me-ICA;NSC 68357;AKOS JY2082906;RARECHEM AL BE 0864;2-Carboxy-1-methyl-1H-indole;1-methyl-2-indolecarboxylicacid;1-METHYLINDOLE-2-CARBOXYLIC ACID;N-METHYL-2-INDOLECARBOXYLIC ACID;1-Methyl-2-indolecarboxylic acid;N-Methylindole-2-carboxylic acid
CBNumber
CB2398286
Molecular Formula
C10H9NO2
Formula Weight
175.18
MOL File
16136-58-6.mol
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1-Methylindole-2-carboxylic acid Property

Melting point:
212-213 °C (dec.) (lit.)
Boiling point:
389.0±15.0 °C(Predicted)
Density 
1.24±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
Crystalline Powder
pka
4.19±0.30(Predicted)
color 
Beige
CAS DataBase Reference
16136-58-6(CAS DataBase Reference)
NIST Chemistry Reference
1-Methylindole-2-carboxylic acid(16136-58-6)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/37/38
Safety Statements 
26
WGK Germany 
3
RTECS 
NL6012400
HazardClass 
IRRITANT
HS Code 
29339980
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
134155
Product name
1-Methylindole-2-carboxylic acid
Purity
98%
Packaging
1g
Price
$82.5
Updated
2023/06/20
Sigma-Aldrich
Product number
134155
Product name
1-Methylindole-2-carboxylic acid
Purity
98%
Packaging
5g
Price
$250
Updated
2023/06/20
TCI Chemical
Product number
M1519
Product name
1-Methylindole-2-carboxylic Acid
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$49
Updated
2024/03/01
TCI Chemical
Product number
M1519
Product name
1-Methylindole-2-carboxylic Acid
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$141
Updated
2024/03/01
TRC
Product number
M313615
Product name
1-Methylindole-2-carboxylic acid
Packaging
1g
Price
$75
Updated
2021/12/16
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1-Methylindole-2-carboxylic acid Chemical Properties,Usage,Production

Chemical Properties

Beige crystalline powder

Uses

• ;Reactant for preparation of keto-indoles as novel indoleamine 2,3-dioxygenase (IDO) inhibitors1• ;Reactant for synthesis of fenbufen and ethacrynic acid derivatives as potential antitumor agents via amide coupling reactions2• ;Reactant for diastereoselective synthesis of vinylated heterocycles via ruthenium-catalyzed oxidative vinylation with alkenes3• ;Reactant for synthesis of 2,3-dihalo indoles via hypervalent iodine mediated decarboxylative halogenation4• ;Reactant for preparation of α-ketoamides as cathepsin S inhibitors with potential applications ag

Uses

  • Reactant for preparation of keto-indoles as novel indoleamine 2,3-dioxygenase (IDO) inhibitors
  • Reactant for synthesis of fenbufen and ethacrynic acid derivatives as potential antitumor agents via amide coupling reactions
  • Reactant for diastereoselective synthesis of vinylated heterocycles via ruthenium-catalyzed oxidative vinylation with alkenes
  • Reactant for synthesis of 2,3-dihalo indoles via hypervalent iodine mediated decarboxylative halogenation
  • Reactant for preparation of α-ketoamides as cathepsin S inhibitors with potential applications against tumor invasion and angiogenesis
  • Reactant for preparation of anthranilic acid mimics as bacterial translation inhibitors

General Description

1-Methylindole-2-carboxylic acid reacts with thionyl chloride to yield sulfinyl chlorides.

1-Methylindole-2-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Methylindole-2-carboxylic acid Suppliers

UkrOrgSynthesis Ltd.
Tel
--
Fax
--
Email
y.barysheva@ukrorgsynth.com
Country
Ukraine
ProdList
6230
Advantage
38
CAS Organic Company
Tel
--
Fax
--
Email
Sales@casorganic.com
Country
Ukraine
ProdList
5026
Advantage
34
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View Lastest Price from 1-Methylindole-2-carboxylic acid manufacturers

Career Henan Chemical Co
Product
1-Methylindole-2-carboxylic acid 16136-58-6
Price
US $6.60/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
1kg -1000kg
Release date
2020-01-02

16136-58-6, 1-Methylindole-2-carboxylic acidRelated Search:


  • RARECHEM AL BE 0864
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  • 1-methyl-2-indolecarboxylicacid
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  • AKOS JY2082906
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  • 1-Me-ICA
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  • 1-Methylindole-2-carboxylic acid, 1-Methyl-1H-indole-2-carboxylic acid, 99%
  • 1-Methylindole-2-carboxylic acid ,98%
  • N-Methylindole-2-carboxylic acid
  • NSC 68357
  • 2-Carboxy-1-methyl-1H-indole
  • 1-Methylindole-2-carboxylicAcid&gt
  • 16136-58-6
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