ChemicalBook > CAS DataBase List > Metoprolol Acid

Metoprolol Acid

Product Name
Metoprolol Acid
CAS No.
56392-14-4
Chemical Name
Metoprolol Acid
Synonyms
Atenolol Acid;Metoprolol Acid Sodium Salt;2-(4-(2-Hydroxy-3-(isopropylamino)propoxy)phenyl)acetic acid; H 117/04;SL 77-010;Atenlol Imp G;Metoprolol Acid;Atenolol USP RC C;ATENOLOL EP IMP G;Atenlol Impurity G
CBNumber
CB11176473
Molecular Formula
C14H21NO4
Formula Weight
267.32
MOL File
56392-14-4.mol
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Metoprolol Acid Property

Melting point:
174-176°C
Boiling point:
477.1±40.0 °C(Predicted)
Density 
1.159±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMSO (Slightly), Methanol (Slightly, Heated), Water (Slightly)
form 
Solid
pka
4.41±0.10(Predicted)
color 
White to Off-White
Stability:
Hygroscopic
CAS DataBase Reference
56392-14-4
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Safety

Hazard Codes 
Xn
Risk Statements 
22
WGK Germany 
3
RTECS 
CY1634360
Toxicity
LD50 intravenous in dog: > 500mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
902853
Product name
Metoprolol acid
Purity
≥95%
Packaging
10MG
Price
$222.6
Updated
2024/03/01
Sigma-Aldrich
Product number
77947
Product name
4-(2-Hydroxy-3-isopropylaminopropoxy)phenylacetic acid
Purity
analytical standard
Packaging
25mg
Price
$734
Updated
2024/03/01
TRC
Product number
M338785
Product name
MetoprololAcid
Packaging
25mg
Price
$410
Updated
2021/12/16
Usbiological
Product number
017611
Product name
Metoprolol Acid
Packaging
10mg
Price
$460
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0027319
Product name
METOPROLOL ACID
Purity
95.00%
Packaging
5MG
Price
$501.44
Updated
2021/12/16
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Metoprolol Acid Chemical Properties,Usage,Production

Chemical Properties

Off-white Solid

Uses

The acidic inactive metabolite of Metoprolol

Uses

4-(2-Hydroxy-3-isopropylaminopropoxy)phenylacetic acid may be used as an analytical standard for the determination of the analyte in environmental water samples, wastewater samples, and human and animal biological samples by various chromatography techniques.

Definition

ChEBI: A monocarboxylic acid that is phenylacetic acid substituted by a 2-hydroxy-3-(propan-2-ylamino)propoxy group at position 4. It is a metabolite of the drug atenolol.

General Description

4-(2-Hydroxy-3-isopropylaminopropoxy)phenylacetic acid is a metabolite of the selective β-1 blocker drug metoprolol.

Metoprolol Acid Preparation Products And Raw materials

Raw materials

Preparation Products

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56392-14-4, Metoprolol AcidRelated Search:

Ginkgo biloba extract 3-[2-Hydroxy-3-[4-(2-methoxyethyl)phenoxy]propoxy]-1-isopropylamino-2-propanol 3-[4-(2-Methoxyethyl)phenoxy]- 1,3-Bis[(1-Methylethyl)aMino]-2-propanol Dihydrochloride Amlodipine Nifedipine 1-(2,6-Dimethylphenoxy)-2-propanamine Metoprolol Impurity 14 2-[4-(2,3-DIHYDROXYPROPOXY)PHENYL]ACETAMIDE C-Desmethyl Atenolol 2-[4-(2,3-EPOXYPROPOXY)PHENYL]ACETAMIDE 1,3-Bis[4-(2-methoxyethyl)phenoxy]- 1,1[(1-Methylethyl)imino]bis[3-[4-(2-methoxyethyl)phenoxy]-2-propanol_x000b_(Mixture of diastereomers) 4-TERT-BUTOXYPHENETHYL ALCOHOL C-Desmethyl Metoprolol MCYVNMKALCGOTK-UHFFFAOYSA-N 1-(4-Ethenylphenoxy)-3-[(1-Methylethyl)aMino]-2-propanole [[p-(2-methoxyethyl)phenoxy]methyl]oxirane

  • H 117/04
  • 4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-benzeneacetic Acid
  • Atenolol Acid
  • Metoprolol Acid
  • SL 77-010
  • Atenolol IMpurity –G(EP)
  • Atenolol Related CoMpound C
  • 4-(3-Isopropylamino-2-hydroxypropoxy)benzeneacetic acid
  • Atenolol EP Impurity G
  • 2-[4-[(2RS)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]acetic acid
  • 2-[4-[(2RS)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]acetic acid sodium salt
  • Metoprolol Acid Sodium Salt
  • Atenolol Impurity 7（Atenolol EP Impurity G）
  • 2-[4-[(2RS)-2-Hydroxy-3-[(1-methyle
  • Atenolol USP RC C
  • Benzeneacetic acid, 4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-
  • 2-(4-(2-Hydroxy-3-(isopropylamino)propoxy)phenyl)acetic acid
  • Atenlol Imp G
  • Atenlol Impurity G
  • Atenolol EP Impurity G/ Atenolol Related Compound C (Metoprolol Acid)
  • Atenolol EP Impurity GQ: What is Atenolol EP Impurity G Q: What is the CAS Number of Atenolol EP Impurity G
  • Atenolol Impurity 7
  • Atenolol Related Compound C (2-{4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl} acetic acid) (1044436)
  • Atenolol USP Related Compound C
  • ATENOLOL EP IMP G
  • 56392-14-4
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals