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Amlodipine

Product Name
Amlodipine
CAS No.
88150-42-9
Chemical Name
Amlodipine
Synonyms
AmL;Isti;LOTREL;Pelmec;besylate;UK-48340;AMlopres;Amlodipin;Intervask;AMLODIPINE
CBNumber
CB9366505
Molecular Formula
C20H25ClN2O5
Formula Weight
408.88
MOL File
88150-42-9.mol
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Amlodipine Property

Melting point:
178-179°C
Boiling point:
527.2±50.0 °C(Predicted)
Density 
1.227±0.06 g/cm3(Predicted)
RTECS 
US7968329
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
pka
pKa 8.6 (Uncertain)
form 
Almost white crystal powder
Water Solubility 
75.3 mg/L
CAS DataBase Reference
88150-42-9(CAS DataBase Reference)
EPA Substance Registry System
3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester (88150-42-9)
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Safety

HazardClass 
IRRITANT
HazardClass 
6.1
Hazardous Substances Data
88150-42-9(Hazardous Substances Data)
Toxicity
TDLo orl-chd: 400 mg/kg:BPR AJEMEN 18,581,2000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Hazard statements

H301Toxic if swalloed

H318Causes serious eye damage

H373May cause damage to organs through prolonged or repeated exposure

H400Very toxic to aquatic life

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Alfa Aesar
Product number
J62242
Product name
Amlodipine, 97+%
Packaging
1g
Price
$111
Updated
2021/03/22
Alfa Aesar
Product number
J62242
Product name
Amlodipine, 97+%
Packaging
5g
Price
$422
Updated
2021/03/22
Cayman Chemical
Product number
14838
Product name
Amlodipine
Purity
≥98%
Packaging
5g
Price
$330
Updated
2021/03/22
Cayman Chemical
Product number
14838
Product name
Amlodipine
Purity
≥98%
Packaging
1g
Price
$88
Updated
2021/03/22
Alfa Aesar
Product number
J62242
Product name
Amlodipine, 97+%
Packaging
10g
Price
$550
Updated
2021/03/22
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Amlodipine Chemical Properties,Usage,Production

Chemical Properties

Yellow Solid

Uses

A dihydropyridine calcium channel blocker; activity resides mainly in the (-)-isomer.

Uses

anti-hypertensive;calcium channel blocker

Uses

A deuterated dihydropyridine calcium channel blocker.;Application of Labeled APIs: Labeled Amlodipine, intended for use as an internal standard for the quantification of Amlodipine by GC- or LC-mass spectrometry.

Definition

ChEBI: A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.

brand name

Norvasc (Pfizer).

General Description

Amlodipine, 2-[, for the treatment of hypertension. Amlodipineis also marketed as a combination therapy with atorvastatinunder the tradename Norvasc for the management of highcholesterol and high blood pressure.

Hazard

Human systemic effects.

Safety Profile

Human systemic effects. Whenheated to decomposition it emits toxic vapors of NOx andCl-.

Amlodipine Preparation Products And Raw materials

Raw materials

Preparation Products

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Amlodipine Suppliers

Hubei Dingcheng Shijia Pharmaceutical Chemical Co., Ltd.
Tel
13995602569
Email
hbdcsjyy@163.com
Country
CHINA
ProdList
99
Advantage
58
Shenzhen Kaimingke Biotechnology Co., Ltd.
Tel
181-26439142-
Email
1144496688@QQ.COM;
Country
China
ProdList
171
Advantage
58
Anhui Dexinjia Biopharm Co., Ltd
Tel
0531-82375878-
Email
3385307203@qq.com
Country
China
ProdList
268
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833- ;010-82848833-
Fax
86-10-82849933
Email
jkinfo@jkchemical.com;market6@jkchemical.com
Country
China
ProdList
96815
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15877
Advantage
69
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 qq:2355568890
Fax
0086-21-50182339
Email
sales@demochem.com; export1@demochem.com
Country
China
ProdList
2582
Advantage
57
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057-
Fax
0757-86311057
Email
sales.gd@hwrkchemical.com
Country
China
ProdList
17295
Advantage
55
Energy Chemical
Tel
021-58432009-
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
43494
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35909
Advantage
56
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078;021-50426030
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
10006
Advantage
60
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View Lastest Price from Amlodipine manufacturers

Jinan Ande Pharmaceutical Co.,Ltd.
Product
Amlodipine 88150-42-9
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
500
Release date
2021-08-09
Dideu Industries Group Limited
Product
Amlodipine USP/EP/BP 88150-42-9
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons min
Release date
2021-08-06
Zhuozhou Wenxi import and Export Co., Ltd
Product
Amlodipine 88150-42-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10

88150-42-9, AmlodipineRelated Search:


  • 3,5-pyridinedicarboxylicacid,1,4-dihydro-2-((2-aminoethoxy)methyl)-4-(2-chlor
  • Amlodipine base (crystalline)
  • (R)-3-ethyl 5-methyl 2
  • 3-ethyl5-methylester
  • LOTREL
  • methyl ethyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
  • AMLODIPINE
  • AMLODIPINE BASE
  • Amlodipin
  • besylate
  • AMLODIPINE MM(CRM STANDARD)
  • Amlodipine&Int
  • AmlodipineBesylate/Maleate
  • 3,5-Pyridinedicarboxylic acid, 2-(2-aminoethoxy)methyl-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester
  • ethyl methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
  • Pelmec
  • Racemic Amlodipine
  • 3,5-pyridinedicarboxylic acid, 1,4-dihydro-2-((2-aminoethoxy)methyl)-4-(2-chlor 3-ethyl 5-methyl ester
  • 3-ethyl 5-Methyl 2-((2-aMinoethoxy)Methyl)-4-(2-chlorophenyl)-6-Methyl-1,4-dihydropyridine-3,5-dicarboxylate
  • Amlodipine Besilate Imp.(EP)
  • 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid O3-ethyl O5-methyl ester
  • Amlodipine besilate (JAN)
  • Amlodipine besylate (USAN)
  • Isti
  • O3-ethyl O5-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
  • Amlodipine, >=99%
  • (RS)-3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
  • 4-(2-chloro-phenyl-2(3-(1,3-dioxo-l,3-dihydro-isoindol-2yl-prpionyl)6-methyl-pyridin3, 5-dicarboxylic acid-ethyl-ethyl ester 5-methyl ester (p-2) of RS amlodipine besylate
  • AMlodipine besylate, >95%
  • Amlodipine Besylate IMP
  • phytoxanthin
  • Amlodipine (base and/or unspecified salts)
  • AMLODIPINE (BASE & SALTS)
  • Amlodipine ( Amlodipine Benzenesulfonate)
  • 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydro-3,5-pyridinedicarboxylic acid 5-methyl 3-ethyl ester
  • UK-48340
  • UK-48340-11
  • 2-(2-Aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid 3-ethyl=5-methyl ester
  • 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydro-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester
  • 2-Methyl-4-(2-chlorophenyl)-6-[[(2-aminoethyl)oxy]methyl]-1,4-dihydro-3,5-pyridinedicarboxylic acid 3-methyl 5-ethyl ester
  • 4-(2-Chlorophenyl)-2-methyl-6-(2-aminoethoxymethyl)-1,4-dihydro-3,5-pyridinedicarboxylic acid 3-methyl 5-ethyl ester
  • 4-(2-Chlorophenyl)-6-methyl-2-(2-aminoethoxymethyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-ethyl 5-methyl ester
  • 3-ethyl 5-Methyl (4S)-2-[(2-aMinoethoxy)Methyl]-4-(2-chlorophenyl)-6-Methyl-1,4-dihydropyridine-3,5-dicarboxylate
  • AMlodipine(Norvasc)
  • AMlodiping Besylate
  • (R,S)-AMlodipine
  • AMlopres
  • Intervask
  • 2-((2-Aminoethoxy)methyl)-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester
  • AMLODIPINE (RS)-3-ETHYL-5-METHYL-2[(2-AMINOETHOXY)METHYL]-4-(2-CHLOROPHENYL)-6-METHYL-1,4-DIHYDROPYRIDINE-3,5-DICARBOXYLATE
  • AMlodipine-d4 Maleate
  • [2H4]-Amlodipine besylate
  • AmL
  • odipine besyL
  • Amlodipine Solution in Methanol, 100μg/mL
  • Amlodipine USP/EP/BP
  • 88150-42-9
  • 38150-49-9