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Brofaromine

Product Name
Brofaromine
CAS No.
63638-91-5
Chemical Name
Brofaromine
Synonyms
4-(7-bromo-5-methoxybenzofuran-2-yl)piperidine;Piperidine, 4-(7-bromo-5-methoxy-2-benzofuranyl)-;4-(7-Bromo-5-methoxy-1-benzofuran-2-yl)piperidine
CBNumber
CB11178149
Molecular Formula
C14H16BrNO2
Formula Weight
310.19
MOL File
63638-91-5.mol
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Brofaromine Property

Boiling point:
404.0±45.0 °C(Predicted)
Density 
1.386±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: 250 mg/mL (805.96 mM)
form 
Solid
pka
9.99±0.10(Predicted)
color 
Off-white to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-6637
Product name
Brofaromine
Purity
98.55%
Packaging
5mg
Price
$245
Updated
2021/12/16
ChemScene
Product number
CS-6637
Product name
Brofaromine
Purity
98.55%
Packaging
10mg
Price
$395
Updated
2021/12/16
ChemScene
Product number
CS-6637
Product name
Brofaromine
Purity
98.55%
Packaging
50mg
Price
$980
Updated
2021/12/16
ChemScene
Product number
CS-6637
Product name
Brofaromine
Purity
98.55%
Packaging
100mg
Price
$1500
Updated
2021/12/16
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Brofaromine Chemical Properties,Usage,Production

Biological Activity

Brofaromine (CGP 11305A) is a monoamine oxidase (MAO) inhibitor, inhibits MAO-A with IC50 of 0.2 μM.

in vitro

In order to assess whether the protective effect is related to the inhibition of the MAO-A or due to another mechanism, the effect of Brofaromine (CGP 11305A, BRO) is determined on the activity of MAO-A in cultured cortical cells. It shows, firstly, that cultured cortical cells have a significant MAO-A activity, and secondly, that Brofaromine inhibits the enzyme in a concentration-dependent manner. The IC 50 is 0.19 μM for Brofaromine . Hill coefficient is 0.96. The enzyme is almost completely inhibited at 10 μM . Brofaromine inhibits MAO-A activity of our cultured cortical cells in a concentration-dependent manner. The IC 50 range of Brofaromine is 0.01 μM to 0.1 μM.

target

IC50: 0.2 μM (MAO-A)

Brofaromine Preparation Products And Raw materials

Raw materials

Preparation Products

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Brofaromine Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
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32161
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TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38631
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Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
52924
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MedChemExpress
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Fax
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Email
sales@medchemexpress.com
Country
United States
ProdList
6398
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63638-91-5, BrofaromineRelated Search:


  • 4-(7-bromo-5-methoxybenzofuran-2-yl)piperidine
  • 4-(7-Bromo-5-methoxy-1-benzofuran-2-yl)piperidine
  • Piperidine, 4-(7-bromo-5-methoxy-2-benzofuranyl)-
  • 63638-91-5