Chimaphilin
- Product Name
- Chimaphilin
- CAS No.
- 482-70-2
- Chemical Name
- Chimaphilin
- Synonyms
- 7-Dimethyl-1;2,7-dimethylnaphthalene-1,4-dione;2,7-Dimethyl-1,4-naphthalenedione;1,4-Naphthalenedione, 2,7-dimethyl-
- CBNumber
- CB11178255
- Molecular Formula
- C12H10O2
- Formula Weight
- 186.21
- MOL File
- 482-70-2.mol
Chimaphilin Property
- Melting point:
- 113.5-114.5°; mp 232-233°
- Boiling point:
- 346.8±42.0 °C(Predicted)
- Density
- 1.187
N-Bromosuccinimide Price
- Product number
- PXT0002103
- Product name
- CHIMAPHILIN
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $501.67
- Updated
- 2021/12/16
Chimaphilin Chemical Properties,Usage,Production
Uses
Chimaphilin is an IGF-1R inhibitor (IC50: 0.086 μM). Chimaphilin has antifungal, antioxidant and anticancer activities. Chimaphilin inhibits the growth of both drug-sensitive and drug-resistant osteosarcoma cell lines. Chimaphilin can induce cancer cell apoptosis. Chimaphilin is a main component of pyrola[1][2].
Definition
ChEBI: Chimaphylin is a member of 1,4-naphthoquinones.
References
[1] Daqian W, et al. Chimaphilin inhibits proliferation and induces apoptosis in multidrug resistant osteosarcoma cell lines through insulin-like growth factor-I receptor (IGF-IR) signaling. Chem Biol Interact. 2015 Jul 25;237:25-30. DOI:10.1016/j.cbi.2015.05.008
[2] Ma WD, et al. Chimaphilin induces apoptosis in human breast cancer MCF-7 cells through a ROS-mediated mitochondrial pathway. Food Chem Toxicol. 2014 Aug;70:1-8. DOI:10.1016/j.fct.2014.04.014
Chimaphilin Preparation Products And Raw materials
Raw materials
Preparation Products
Chimaphilin Suppliers
- Tel
- +1 (866) 930-6790
- Fax
- +1 (866) 333-9607
- info@adooq.com
- Country
- United States
- ProdList
- 2782
- Advantage
- 58
- Tel
- +1-781-999-5354;
- support@targetmol.com
- Country
- United States
- ProdList
- 39035
- Advantage
- 58
- Tel
- --
- Fax
- --
- info@Alfa-Chemistry.com
- Country
- United States
- ProdList
- 6814
- Advantage
- 0