Forphenicine

Product Name: Forphenicine
CAS No.: 57784-96-0
Chemical Name: Forphenicine
Synonyms: Forphenicine;L-(+)-Forphenicin;α-Amino-4-formyl-3-hydroxybenzeneacetic acid;Benzeneacetic acid, α-amino-4-formyl-3-hydroxy-, (αS)-
CBNumber: CB11178811
Molecular Formula: C9H9NO4
Formula Weight: 195.17
MOL File: 57784-96-0.mol

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Forphenicine Property

Boiling point:: 419.4±45.0 °C(Predicted)
Density: 1.485±0.06 g/cm3(Predicted)
storage temp.: -20°C
pka: 1.62±0.10(Predicted)
form: A solid

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Hazard and Precautionary Statements (GHS)

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Forphenicine Chemical Properties,Usage,Production

Biological Activity

Forphenicine is a bacterial metabolite that has been found in S. fulvoviridis and an inhibitor of alkaline phosphatase (IC50 = 0.036 μg/ml for the chicken intestine enzyme).1 It inhibits the growth of HL-60 leukemia cells when used at a concentration of 10 μM.2 Forphenicine (50 and 500 μg/animal) increases survival in a guinea pig model of experimental autoimmune encephalomyelitis (EAE).3

References

1.Aoyagi, T., Yamamoto, T., Kojiri, K., et al.Forphenicine, and inhibitor of alkaline phosphatase produced by actinomycetesJ. Antibiot. (Tokyo)31(3)244-246(1978) 2.Miura, K., Sawa, T., Takeuchi, T., et al.Effects of enzyme inhibitors in inhibiting the growth and inducing the differentiation of human promyelocytic leukemia cells, HL-60J Antibiot (Tokyo)39(5)734-735(1986) 3.Aoyagi, T., Wada, T., Nagai, M., et al.Low-molecular-weight enzyme inhibitors suppress the development of experimental allergic encephalomyelitisExperientia40(12)1405-1407(1984)

Forphenicine Preparation Products And Raw materials

Raw materials

Preparation Products

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Forphenicine Suppliers

China 5 United States 2 Global 7

ChemeGen 中国

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 6973
Advantage: 58

Beijing Biocreative Technology Co., Ltd.

Tel: 15522676233
Email: 3007606172@qq.com
Country: China
ProdList: 1248
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24648
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11974
Advantage: 58

TargetMol Chemicals Inc.

Tel: +8613564774135
Email: zijue.cai@tsbiochem.com
Country: United States
ProdList: 19863
Advantage: 58

57784-96-0, ForphenicineRelated Search:

(S)-4-CARBOXY-3-HYDROXYPHENYLGLYCINE 2-AMINO-2-(4-METHYLPHENYL)ACETIC ACID (RS)-4-CARBOXY-3-HYDROXYPHENYLGLYCINE Forphenicine

L-(+)-Forphenicin

Forphenicine

α-Amino-4-formyl-3-hydroxybenzeneacetic acid

Benzeneacetic acid, α-amino-4-formyl-3-hydroxy-, (αS)-

57784-96-0