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Dicyclohexyl carbonate

Product Name
Dicyclohexyl carbonate
CAS No.
4427-97-8
Chemical Name
Dicyclohexyl carbonate
Synonyms
Dicyclohexyl carbonate;Candesartan Impurity 27;Carbonic acid dicyclohexyl ester
CBNumber
CB11247298
Molecular Formula
C13H22O3
Formula Weight
226.31
MOL File
4427-97-8.mol
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Dicyclohexyl carbonate Property

Melting point:
43-44 °C
Boiling point:
340.2±9.0 °C(Predicted)
Density 
1.04±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
D438505
Product name
DicyclohexylCarbonate
Packaging
100mg
Price
$160
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD142457
Product name
Dicyclohexyl carbonate
Packaging
5G
Price
$216
Updated
2021/12/16
AK Scientific
Product number
9665CA
Product name
Dicyclohexylcarbonate
Packaging
5g
Price
$231
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD142457
Product name
Dicyclohexyl carbonate
Packaging
10g
Price
$375
Updated
2021/12/16
Ark Pharm
Product number
P000613819
Product name
Dicyclohexyl carbonate
Purity
95+%
Packaging
10g
Price
$439
Updated
2021/12/16
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Dicyclohexyl carbonate Chemical Properties,Usage,Production

Uses

Dicyclohexyl Carbonate is used as a reagent in the synthesis of colon specific reduction sensitive polymers for pharmaceuticals.

Synthesis

124-38-9

108-93-0

4427-97-8

Example 18: Synthesis of dicyclohexyl carbonate by reaction of cyclohexanol, CO2 and propylene oxide at 80 bar CO2 pressure and 150 °C using BWCsoo as catalyst. This was done as follows: propylene oxide (10.17 g, 0.175 mol), cyclohexanol (140.81 g, 1.40 mol) and BWC80o catalyst (15.0 g, 10% wt/wt) were added to a 700 ml autoclave vessel and sealed. Subsequently, the autoclave vessel was pressurized with CO2, heated to 150 °C with continuous stirring and maintained at 80 bar pressure, and the reaction continued for 24 hours. Upon completion of the reaction, the reaction mixture was post-treated according to the method described in Example 1. By quantitatively analyzing the reaction mixture, the amount of dicyclohexyl carbonate produced was measured to be 9.55 g (42.0 mmol), with a yield of 24% calculated on the basis of propylene oxide.

References

[1] Patent: EP1460056, 2004, A1. Location in patent: Page 32-33
[2] Patent: WO2015/114474, 2015, A1. Location in patent: Page/Page column 18

Dicyclohexyl carbonate Preparation Products And Raw materials

Raw materials

Preparation Products

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Dicyclohexyl carbonate Suppliers

YangZhou Ruihong Biotech Co., Ltd.
Tel
0514-015380367604 15380367604
Fax
0514-83828236
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sales@ruibobiotech.com
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China
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Zhengzhou Gecko Scientific Inc.
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0371-63336364 17344886665
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0371-65511872
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209932355@qq.com
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China
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489
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Zhengzhou Guancheng Laboratory equipment Sales
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0371-88888888 272369594
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China
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4960
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Alfa Chemistry
Tel
1-516-6625404
Fax
1-516-927-0118
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support@alfa-chemistry.com
Country
United States
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9171
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60
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
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Country
China
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71826
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Jiangsu aikang biomedical research and development co., LTD
Tel
025-58859352 13155353615
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qzhang@aikonchem.com
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China
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Henan qinpeng technology co., ltd
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18839185240
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2148319152@qq.com
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China
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Energy Chemical
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021-58432009 400-005-6266
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021-58436166
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marketing@energy-chemical.com
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China
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58
Bide Pharmatech Ltd.
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400-1647117 13681763483
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product02@bidepharm.com
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China
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Bide Pharmatech Ltd.
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400-6005915
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sales@picasso-e.com
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China
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4427-97-8, Dicyclohexyl carbonateRelated Search:


  • Dicyclohexyl carbonate
  • Carbonic acid dicyclohexyl ester
  • Candesartan Impurity 27
  • 4427-97-8