ChemicalBook > CAS DataBase List > 2-phenylsulfanylethyl methyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-d icarboxylate

2-phenylsulfanylethyl methyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-d icarboxylate

Product Name
2-phenylsulfanylethyl methyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-d icarboxylate
CAS No.
123875-01-4
Chemical Name
2-phenylsulfanylethyl methyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-d icarboxylate
Synonyms
2-phenylsulfanylethyl methyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-d icarboxylate;3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,4,6-trimethyl-, 3-methyl 5-[2-(phenylthio)ethyl] ester
CBNumber
CB11261151
Molecular Formula
C19H23NO4S
Formula Weight
361.46
MOL File
123875-01-4.mol
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2-phenylsulfanylethyl methyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-d icarboxylate Property

storage temp. 
Desiccate at -20°C
solubility 
Soluble to 100 mM in DMSO and to 100 mM in ethanol
form 
Powder
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
P216605
Product name
PCA4248
Packaging
10mg
Price
$115
Updated
2021/12/16
ApexBio Technology
Product number
B6355
Product name
PCA4248
Packaging
10mg
Price
$219
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0000758
Product name
PCA 4248
Purity
95.00%
Packaging
10MG
Price
$653.68
Updated
2021/12/16
ApexBio Technology
Product number
B6355
Product name
PCA4248
Packaging
50mg
Price
$921
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0000758
Product name
PCA 4248
Purity
95.00%
Packaging
50MG
Price
$976.27
Updated
2021/12/16
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2-phenylsulfanylethyl methyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-d icarboxylate Chemical Properties,Usage,Production

Uses

PCA 4248 is a competitive inhibitor of PAF at the PAF-R level.

Definition

ChEBI: 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid O3-methyl ester O5-[2-(phenylthio)ethyl] ester is a dihydropyridine.

Biological Activity

A specific PAF antagonist, more potent than the ginkolide BN-52021. Inhibits rabbit platelet aggregation with an IC 50 value of 1.05 μ M and has no significant activity on Ca 2+ channels. Active in vivo , antagonising PAF-induced systemic hypotension and protein-plasma extravasation in rats.

2-phenylsulfanylethyl methyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-d icarboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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2-phenylsulfanylethyl methyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-d icarboxylate Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44808
Advantage
58
Changzhou Bojia Biomedical Technology Co., Ltd.
Tel
2122619822
Email
czbjpharma@126.com
Country
China
ProdList
18478
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24647
Advantage
58

123875-01-4, 2-phenylsulfanylethyl methyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-d icarboxylateRelated Search:


  • 2-phenylsulfanylethyl methyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-d icarboxylate
  • 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,4,6-trimethyl-, 3-methyl 5-[2-(phenylthio)ethyl] ester
  • 123875-01-4
  • C19H23NO4S