ChemicalBook > CAS DataBase List > 2-phenylsulfanylethyl methyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-d icarboxylate
2-phenylsulfanylethyl methyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-d icarboxylate
- Product Name
- 2-phenylsulfanylethyl methyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-d icarboxylate
- CAS No.
- 123875-01-4
- Chemical Name
- 2-phenylsulfanylethyl methyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-d icarboxylate
- Synonyms
- 2-phenylsulfanylethyl methyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-d icarboxylate;3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,4,6-trimethyl-, 3-methyl 5-[2-(phenylthio)ethyl] ester
- CBNumber
- CB11261151
- Molecular Formula
- C19H23NO4S
- Formula Weight
- 361.46
- MOL File
- 123875-01-4.mol
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2-phenylsulfanylethyl methyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-d icarboxylate Property
- storage temp.
- Desiccate at -20°C
- solubility
- Soluble to 100 mM in DMSO and to 100 mM in ethanol
- form
- Powder
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N-Bromosuccinimide Price
TRC
- Product number
- P216605
- Product name
- PCA4248
- Packaging
- 10mg
- Price
- $115
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- B6355
- Product name
- PCA4248
- Packaging
- 10mg
- Price
- $219
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- INB0000758
- Product name
- PCA 4248
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $653.68
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- B6355
- Product name
- PCA4248
- Packaging
- 50mg
- Price
- $921
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- INB0000758
- Product name
- PCA 4248
- Purity
- 95.00%
- Packaging
- 50MG
- Price
- $976.27
- Updated
- 2021/12/16
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2-phenylsulfanylethyl methyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-d icarboxylate Chemical Properties,Usage,Production
Uses
PCA 4248 is a competitive inhibitor of PAF at the PAF-R level.
Definition
ChEBI: 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid O3-methyl ester O5-[2-(phenylthio)ethyl] ester is a dihydropyridine.
Biological Activity
A specific PAF antagonist, more potent than the ginkolide BN-52021. Inhibits rabbit platelet aggregation with an IC 50 value of 1.05 μ M and has no significant activity on Ca 2+ channels. Active in vivo , antagonising PAF-induced systemic hypotension and protein-plasma extravasation in rats.
2-phenylsulfanylethyl methyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-d icarboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
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2-phenylsulfanylethyl methyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-d icarboxylate Suppliers
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123875-01-4, 2-phenylsulfanylethyl methyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-d icarboxylateRelated Search:
dimethyl 1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylate
2-(Phenylthio)Ethyl Acrylate
2-phenylsulfanylethyl methyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-d icarboxylate
2,4-DIMETHYL-1,4-DIHYDRO-PYRIDINE-3-CARBOXYLIC ACID ETHYL ESTER
2-(METHYLTHIO)ETHYL METHACRYLATE