6-Nitro-2-benzothiazolinone
- Product Name
- 6-Nitro-2-benzothiazolinone
- CAS No.
- 28620-12-4
- Chemical Name
- 6-Nitro-2-benzothiazolinone
- Synonyms
- 6-Nitrobenzothiazolone;6-NITRO-BENZOTHIAZOL-2-ONE;6-nitrobenzothiazolin-2-one;6-NITRO-2-BENZOTHIAZOLINONE;6-nitro-2H-benzothiazolinone;6-nitro-2(3H)-benzothiazolone;2-Hydroxy-6-nitrobenzothiazol;2(3H)-Benzothiazolone,6-nitro;6-Nitrobenzo[d]thiazol-2(3H)-one;6-nitro-3H-1,3-benzothiazol-2-one
- CBNumber
- CB1129843
- Molecular Formula
- C7H4N2O3S
- Formula Weight
- 196.18
- MOL File
- 28620-12-4.mol
6-Nitro-2-benzothiazolinone Property
- Melting point:
- 246 °C (dec.) (lit.)
- Density
- 1.603±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- form
- viscous liquid
- pka
- 8.78±0.20(Predicted)
- Appearance
- Light yellow to yellow Solid
- CAS DataBase Reference
- 28620-12-4(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 441929
- Product name
- 6-Nitro-2-benzothiazolinone
- Packaging
- 1g
- Price
- $21.3
- Updated
- 2023/06/20
- Product number
- N495768
- Product name
- 6-Nitro-2-benzothiazolinone
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- W5127
- Product name
- 6-Nitrobenzo[d]thiazol-2(3H)-one
- Packaging
- 1g
- Price
- $95
- Updated
- 2021/12/16
- Product number
- 8H70-1-0R
- Product name
- 6-Nitro-2-benzothiazolinone
- Packaging
- 1g
- Price
- $175
- Updated
- 2021/12/16
- Product number
- W5127
- Product name
- 6-Nitrobenzo[d]thiazol-2(3H)-one
- Packaging
- 5g
- Price
- $196
- Updated
- 2021/12/16
6-Nitro-2-benzothiazolinone Chemical Properties,Usage,Production
Chemical Properties
White solid
Uses
6-Nitro-2-benzothiazolinone may be used as a starting reagent for the synthesis of 3-alkyl-6-nitro-2-benzothiazolinones.
General Description
6-Nitro-2-benzothiazolinone is a 6-substituted 2-benzothiazolinone.
Synthesis
934-34-9
28620-12-4
General procedure for the synthesis of 6-nitro-2-(3H)-benzothiazolone from 2-hydroxybenzothiazole: 3H-benzothiazol-2-one (10 g, 66 mmol) was added to 70% nitric acid (20 mL), and the reaction was stirred for 3 h at 20 °C. After completion of the reaction, the precipitate was collected by filtration and washed with deionized water. The crude product was purified by recrystallization from anhydrous ethanol. The yield of this synthesis step was 90% and the melting point of the product was 228-229 °C. It was characterized by 1H NMR (300 MHz, DMSO-d6): δ 7.28 (d, J = 8.9 Hz, 1H, H4), 8.18 (dd, J = 8.9 Hz, J = 2.4 Hz, 1H, H5), 8.65 (d, J = 2.5 Hz, 1H, H7), and 12.54 (br s, 1H, NH).13C NMR ( 75 MHz, DMSO-d6) characterization: δ 111.9 (CH), 119.6 (CH), 123.2 (CH), 125.0 (Caro), 142.5 (Caro), 142.9 (Caro), 171.0 (CO).LCMS (ESI-) analysis: calculated value of [M-H+] is 195.0; measured value is 195.0.
References
[1] European Journal of Medicinal Chemistry, 2015, vol. 92, p. 807 - 817
[2] Journal of Heterocyclic Chemistry, 1988, vol. 25, p. 1503 - 1509
[3] Monatshefte fur Chemie, 2011, vol. 142, # 1, p. 67 - 80
[4] Chemistry of Heterocyclic Compounds, 1990, vol. 25, # 11, p. 1294 - 1296
[5] Patent: US2003/40533, 2003, A1
6-Nitro-2-benzothiazolinone Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 6-Nitro-2-benzothiazolinone manufacturers
- Product
- 6-nitrobenzothiazolin-2-one 28620-12-4
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98.5%
- Supply Ability
- 100 tons
- Release date
- 2022-01-14
- Product
- 6-Nitro-2-benzothiazolinone 28620-12-4
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
- Product
- 6-Nitro-2-benzothiazolinone 28620-12-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- Customized
- Release date
- 2019-05-23