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trimethylcolchicinic acid methyl ether

Product Name
trimethylcolchicinic acid methyl ether
CAS No.
3476-50-4
Chemical Name
trimethylcolchicinic acid methyl ether
Synonyms
NSC 201400;Deacetylcolchicine;Desacetylcolchicine;Colchicine Impurity 22;(-)-7-Deacetylcolchicine;(S)-N-Deacetyl Colchicine;(-)-N-Deacetyl Colchicine;Colchicine N-Desacetyl (S)-Isomer;trimethylcolchicinic acid methyl ether;7-AMino-6,7-dihydro-1,2,3,10-tetraMethoxy-benzo[a]heptalen-9(5H)-one
CBNumber
CB11317339
Molecular Formula
C20H23NO5
Formula Weight
357.4
MOL File
3476-50-4.mol
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trimethylcolchicinic acid methyl ether Property

Boiling point:
490.03°C (rough estimate)
Density 
1.2532 (rough estimate)
refractive index 
1.5614 (estimate)
storage temp. 
-20°C Freezer, Under Inert Atmosphere
solubility 
DMSO: 25mg/mL; Ethanol: 25mg/mL
form 
A crystalline solid
pka
8.62±0.40(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H300Fatal if swallowed

H318Causes serious eye damage

H340May cause genetic defects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
21697
Product name
N-Deacetylcolchicine
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
21697
Product name
N-Deacetylcolchicine
Packaging
5mg
Price
$116
Updated
2024/03/01
Cayman Chemical
Product number
21697
Product name
N-Deacetylcolchicine
Packaging
10mg
Price
$199
Updated
2024/03/01
Cayman Chemical
Product number
21697
Product name
N-Deacetylcolchicine
Packaging
25mg
Price
$343
Updated
2024/03/01
TRC
Product number
D198920
Product name
(S)-N-DeacetylColchicine
Packaging
100mg
Price
$685
Updated
2021/12/16
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trimethylcolchicinic acid methyl ether Chemical Properties,Usage,Production

Chemical Properties

Yellow Solid

Uses

An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.

Definition

ChEBI: Deacetylcolchicine is a carbotricyclic compound, an alkaloid and a member of acetamides.

trimethylcolchicinic acid methyl ether Preparation Products And Raw materials

Raw materials

Preparation Products

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trimethylcolchicinic acid methyl ether Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Shanghai TaoSu Biochemical Technology Co., Ltd.
Tel
021-33632979
Fax
021-34692979
Email
info@tsbiochem.com
Country
China
ProdList
8065
Advantage
58
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
Aikon International Limited
Tel
025-58859352 18068836627
Fax
02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
15084
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57412
Advantage
58
Hefei Molake Biotechnology Co., Ltd.
Tel
0551-66336380 18956014586
Fax
055166336380
Email
983438788@qq.com
Country
China
ProdList
2123
Advantage
58
sgtlifesciences pvt ltd
Tel
+8617013299288
Email
dj@sgtlifesciences.com
Country
China
ProdList
12373
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11217
Advantage
58
Shenzhen ruikai de biotechnology co., ltd.
Tel
0755-61348847 17820674378
Fax
0755-21016893
Email
2682116078@qq.com
Country
China
ProdList
7843
Advantage
58
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View Lastest Price from trimethylcolchicinic acid methyl ether manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
trimethylcolchicinic acid methyl ether 3476-50-4
Price
US $9.80/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2024-08-01

3476-50-4, trimethylcolchicinic acid methyl etherRelated Search:


  • trimethylcolchicinic acid methyl ether
  • (S)-7-Amino-6,7-dihydro-1,2,3,10-tetramethoxybenzo[a]heptalen-9(5H)-one
  • Deacetylcolchicine
  • Desacetylcolchicine
  • (S)-N-Deacetyl Colchicine
  • (7S)-7-Amino-1,2,3,10-Tetramethoxy-6,7-Dihydro-5H-Benzo[g]Heptalen-9-One
  • (-)-7-Deacetylcolchicine
  • (7S)-7-AMino-6,7-dihydro-1,2,3,10-tetraMethoxy-benzo[a]heptalen-9(5H)-one
  • NSC 201400
  • 7-AMino-6,7-dihydro-1,2,3,10-tetraMethoxy-benzo[a]heptalen-9(5H)-one
  • Colchicine N-Desacetyl (S)-Isomer
  • Benzo[a]heptalen-9(5H)-one, 7-amino-6,7-dihydro-1,2,3,10-tetramethoxy-, (7S)-
  • (S)-7-Amino-1,2,3,10-tetramethoxy-6,7-dihydrobenzo[a]heptalen-9(5H)-one
  • (-)-N-Deacetyl Colchicine
  • Colchicine Impurity 22
  • 3476-50-4
  • Amines
  • Chiral Reagents
  • Heterocycles
  • Amines, Chiral Reagents, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals