trimethylcolchicinic acid methyl ether

Product Name: trimethylcolchicinic acid methyl ether
CAS No.: 3476-50-4
Chemical Name: trimethylcolchicinic acid methyl ether
Synonyms: NSC 201400;Deacetylcolchicine;Desacetylcolchicine;Colchicine Impurity 22;(-)-7-Deacetylcolchicine;(S)-N-Deacetyl Colchicine;(-)-N-Deacetyl Colchicine;Colchicine N-Desacetyl (S)-Isomer;trimethylcolchicinic acid methyl ether;7-AMino-6,7-dihydro-1,2,3,10-tetraMethoxy-benzo[a]heptalen-9(5H)-one
CBNumber: CB11317339
Molecular Formula: C20H23NO5
Formula Weight: 357.4
MOL File: 3476-50-4.mol

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trimethylcolchicinic acid methyl ether Property

Boiling point:: 490.03°C (rough estimate)
Density: 1.2532 (rough estimate)
refractive index: 1.5614 (estimate)
storage temp.: -20°C Freezer, Under Inert Atmosphere
solubility: DMSO: 25mg/mL; Ethanol: 25mg/mL
form: A crystalline solid
pka: 8.62±0.40(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H300Fatal if swallowed

H318Causes serious eye damage

H340May cause genetic defects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 21697
Product name: N-Deacetylcolchicine
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 21697
Product name: N-Deacetylcolchicine
Packaging: 5mg
Price: $116
Updated: 2024/03/01

Cayman Chemical

Product number: 21697
Product name: N-Deacetylcolchicine
Packaging: 10mg
Price: $199
Updated: 2024/03/01

Cayman Chemical

Product number: 21697
Product name: N-Deacetylcolchicine
Packaging: 25mg
Price: $343
Updated: 2024/03/01

TRC

Product number: D198920
Product name: (S)-N-DeacetylColchicine
Packaging: 100mg
Price: $685
Updated: 2021/12/16

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trimethylcolchicinic acid methyl ether Chemical Properties,Usage,Production

Chemical Properties

Yellow Solid

Uses

An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.

Definition

ChEBI: Deacetylcolchicine is a carbotricyclic compound, an alkaloid and a member of acetamides.

trimethylcolchicinic acid methyl ether Preparation Products And Raw materials

Raw materials

Preparation Products

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trimethylcolchicinic acid methyl ether Suppliers

Canada 1 China 21 India 5 United Kingdom 1 United States 3 Global 31

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3476-50-4, trimethylcolchicinic acid methyl etherRelated Search:

GLORIOSINE Colchicine DEMECOLCINE COLCHICOSIDE COLCHICINE, [RING C, METHOXY-14C] DEMECOLCINE HYDROGEN BROMIDE SALT COLCHICINE-D6 COLCHICINE, [RING C, METHOXY-3H] DEMECOLCINE-D6 trimethylcolchicinic acid methyl ether DEMECOLCINE-D3 N-TRIFLUOROACETYL-N-METHYL-DEACETYLCOLCHICINE N-TRIFLUOROACETYL DEACETYLCOLCHICINE COLCHICINE-D3 COLCHICINE METHANETHIOSULFONATE N-(2-MERCAPTOETHYL) DEMECOLCINE TRIMETHYLCOLCHICINIC ACID NBD-DEMECOLCIN

trimethylcolchicinic acid methyl ether

(S)-7-Amino-6,7-dihydro-1,2,3,10-tetramethoxybenzo[a]heptalen-9(5H)-one

Deacetylcolchicine

Desacetylcolchicine

(S)-N-Deacetyl Colchicine

(7S)-7-Amino-1,2,3,10-Tetramethoxy-6,7-Dihydro-5H-Benzo[g]Heptalen-9-One

(-)-7-Deacetylcolchicine

(7S)-7-AMino-6,7-dihydro-1,2,3,10-tetraMethoxy-benzo[a]heptalen-9(5H)-one

NSC 201400

7-AMino-6,7-dihydro-1,2,3,10-tetraMethoxy-benzo[a]heptalen-9(5H)-one

Colchicine N-Desacetyl (S)-Isomer

Benzo[a]heptalen-9(5H)-one, 7-amino-6,7-dihydro-1,2,3,10-tetramethoxy-, (7S)-

(S)-7-Amino-1,2,3,10-tetramethoxy-6,7-dihydrobenzo[a]heptalen-9(5H)-one

(-)-N-Deacetyl Colchicine

Colchicine Impurity 22

3476-50-4

Amines

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Heterocycles

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