trimethylcolchicinic acid methyl ether
- Product Name
- trimethylcolchicinic acid methyl ether
- CAS No.
- 3476-50-4
- Chemical Name
- trimethylcolchicinic acid methyl ether
- Synonyms
- NSC 201400;Deacetylcolchicine;Desacetylcolchicine;Colchicine Impurity 22;(-)-7-Deacetylcolchicine;(S)-N-Deacetyl Colchicine;(-)-N-Deacetyl Colchicine;Colchicine N-Desacetyl (S)-Isomer;trimethylcolchicinic acid methyl ether;7-AMino-6,7-dihydro-1,2,3,10-tetraMethoxy-benzo[a]heptalen-9(5H)-one
- CBNumber
- CB11317339
- Molecular Formula
- C20H23NO5
- Formula Weight
- 357.4
- MOL File
- 3476-50-4.mol
trimethylcolchicinic acid methyl ether Property
- Boiling point:
- 490.03°C (rough estimate)
- Density
- 1.2532 (rough estimate)
- refractive index
- 1.5614 (estimate)
- storage temp.
- -20°C Freezer, Under Inert Atmosphere
- solubility
- DMSO: 25mg/mL; Ethanol: 25mg/mL
- form
- A crystalline solid
- pka
- 8.62±0.40(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H300Fatal if swallowed
H318Causes serious eye damage
H340May cause genetic defects
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313IF exposed or concerned: Get medical advice/attention.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 21697
- Product name
- N-Deacetylcolchicine
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 21697
- Product name
- N-Deacetylcolchicine
- Packaging
- 5mg
- Price
- $116
- Updated
- 2024/03/01
- Product number
- 21697
- Product name
- N-Deacetylcolchicine
- Packaging
- 10mg
- Price
- $199
- Updated
- 2024/03/01
- Product number
- 21697
- Product name
- N-Deacetylcolchicine
- Packaging
- 25mg
- Price
- $343
- Updated
- 2024/03/01
- Product number
- D198920
- Product name
- (S)-N-DeacetylColchicine
- Packaging
- 100mg
- Price
- $685
- Updated
- 2021/12/16
trimethylcolchicinic acid methyl ether Chemical Properties,Usage,Production
Chemical Properties
Yellow Solid
Uses
An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.
Definition
ChEBI: Deacetylcolchicine is a carbotricyclic compound, an alkaloid and a member of acetamides.