2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine

Product Name: 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
CAS No.: 124489-20-9
Chemical Name: 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
Synonyms: N-OH-PHIP;N2-OH-PhIP;N-HYDROXY-PHIP;N-HYDROXY-2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE;2-(Hydroxyamino)-1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridine;1-Methyl-2-(hydroxyamino)-6-phenyl-1H-imidazo[4,5-b]pyridine;N-(1-methyl-6-phenylimidazo[4,5-b]pyridin-2-yl)hydroxylamine;N-(1-Methyl-6-phenyl-1H-imidazo[4,5-b]pyridine-2-yl)hydroxyamine;2H-Imidazo[4,5-b]pyridin-2-one, 1,3-dihydro-1-methyl-6-phenyl-, oxime
CBNumber: CB11325833
Molecular Formula: C13H12N4O
Formula Weight: 240.26
MOL File: 124489-20-9.mol

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2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine Property

Boiling point:: 421.7±55.0 °C(Predicted)
Density: 1.35±0.1 g/cm3(Predicted)
pka: 11.70±0.40(Predicted)

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Hazard and Precautionary Statements (GHS)

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2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine Chemical Properties,Usage,Production

Uses

2-Hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine is a mutagenic metablite of PhIP. PhIP is the most abundant mutagenic heterocyclic amine in cooked foods. Studies have shown the activation of 2-Hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in the formation of PhIP adducts and 5-OH-PhIP.

Definition

ChEBI: N-hydroxy-PhIP is an imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, hydoxyamino, and phenyl groups, respectively. The active metabolite of the dietary carcinogen PhIP. It has a role as a carcinogenic agent, a mutagen, a genotoxin, a human xenobiotic metabolite, a mouse metabolite, a rat metabolite and a neurotoxin. It is an imidazopyridine and a hydroxylamine. It is functionally related to a PhIP.

2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine Suppliers

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124489-20-9, 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridineRelated Search:

1-Methyl-2-nitro-6-phenylimidazo[4,5-B]pyridine 1H-Imidazo[4,5-b]pyridin-2-amine(9CI) 2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine 1-Methyl-D3-2-nitro-6-phenylimidazo[4,5-B]pyridine 2-Amino-1,6-dimethylimidazo[4,5-b]pyridine 1H-Imidazo[4,5-b]pyridin-2-amine,1-methyl-

N-OH-PHIP

N-HYDROXY-2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE

N-HYDROXY-PHIP

1-Methyl-2-(hydroxyamino)-6-phenyl-1H-imidazo[4,5-b]pyridine

2-(Hydroxyamino)-1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridine

N-(1-Methyl-6-phenyl-1H-imidazo[4,5-b]pyridine-2-yl)hydroxyamine

N-(1-methyl-6-phenylimidazo[4,5-b]pyridin-2-yl)hydroxylamine

N2-OH-PhIP

2H-Imidazo[4,5-b]pyridin-2-one, 1,3-dihydro-1-methyl-6-phenyl-, oxime

124489-20-9