2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE

Product Name: 2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE
CAS No.: 105650-23-5
Chemical Name: 2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE
Synonyms: PHIP;Ccris 2954;Brn 5951264;PhIP, 10 mM in DMSO;N,N-diethyl-3-hydroxy-4-methoxybenzamide;Amino-1-methyl-6-phenylimidazo[4.5-b]pyridine;2-AMINO-1-METHYL-6-PHENYLIMADAZO(4,5-B)PYRIDINE;2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE;2-AMINO-1-METHYL-6-PHENOLIMIDAZO[4,5-B]PYRIDINE;2-Amino-1-methyl-6-phenylimidazo[4,5-β]pyridine
CBNumber: CB4716839
Molecular Formula: C13H12N4
Formula Weight: 224.26
MOL File: 105650-23-5.mol

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2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE Property

Melting point:: 300
Boiling point:: 355.66°C (rough estimate)
Density: 1.2067 (rough estimate)
refractive index: 1.5890 (estimate)
storage temp.: Refrigerator
solubility: DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 15 mg/ml; Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml
form: A crystalline solid
pka: 7.72±0.30(Predicted)
color: White to light yellow
biological source: synthetic
Henry's Law Constant: 3.5×10⁷ mol/(m³Pa) at 25℃, HSDB (2015)
InChI: 1S/C13H12N4/c1-17-11-7-10(9-5-3-2-4-6-9)8-15-12(11)16-13(17)14/h2-8H,1H3,(H2,14,15,16)
InChIKey: UQVKZNNCIHJZLS-UHFFFAOYSA-N
SMILES: NC1=NC2=NC=C(C3=CC=CC=C3)C=C2N1C
CAS DataBase Reference: 105650-23-5(CAS DataBase Reference)
IARC: 2B (Vol. 56) 1993

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Safety

Hazard Codes: T
WGK Germany: WGK 3
Hazard Note: Toxic
HS Code: 29333999
Storage Class: 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications: Acute Tox. 3 Oral
Carc. 2
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Hazardous Substances Data: 105650-23-5(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H331Toxic if inhaled

H335May cause respiratory irritation

H350May cause cancer

H360May damage fertility or the unborn child

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P311Call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SMB01383
Product name: PhIP
Purity: ≥95% (HPLC)
Packaging: 10mg
Price: $260
Updated: 2026/04/30

Cayman Chemical

Product number: 22590
Product name: 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
Purity: ≥98%
Packaging: 1mg
Price: $32
Updated: 2026/04/30

Cayman Chemical

Product number: 22590
Product name: 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
Purity: ≥98%
Packaging: 5mg
Price: $128
Updated: 2026/04/30

Cayman Chemical

Product number: 22590
Product name: 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
Purity: ≥98%
Packaging: 10mg
Price: $208
Updated: 2026/04/30

Cayman Chemical

Product number: 22590
Product name: 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
Purity: ≥98%
Packaging: 1mg
Price: $29
Updated: 2024/03/01

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2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

Carcinogen

Definition

ChEBI: An imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, amino, and phenyl groups, respectively. It is the most abundant of the mutagenic heterocyclic amines found in coo ed meat and fish.

Biological Activity

Carcinogen developed in grilled meats. Induces breast and colon cancer in rats.

Safety Profile

Confirmed carcinogen with experimental carcinogenic data. Mutation data reported. When heated to decomposition it emits toxic vapors of NOx,.

Carcinogenicity

PhIP is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals and supporting genotoxicity data.

2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE Suppliers

Canada 1 China 64 Germany 2 India 1 Switzerland 1 United Kingdom 6 United States 16 USA 1 Global 92

J & K SCIENTIFIC LTD.

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Shanghai Macklin Biochemical Co.,Ltd.

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105650-23-5, 2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINERelated Search:

2-Phenylbenzimidazole-5-sulfonic acid 2-Aminoimidazole 2-Benzothiazolamine 2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE 1-Methyl-D3-2-nitro-6-phenylimidazo[4,5-B]pyridine 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-2-14C N-(DEOXYGUANOSIN-8-YL)-2-AMINO-1-METHYL-D3-6-PHENYLIMIDAZO[4,5-B]PYRIDINE 2-Azido-1-methyl-6-phenylimidazo[4,5-b]pyridine 2-Amino-1-(trideuteromethyl)-6-Phenylimidazo[4,5-b] pyridine N-HYDROXY-2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE 1-Methyl-2-nitro-6-phenylimidazo[4,5-B]pyridine N-(deoxyguanosin-8-yl)-2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine 2-amino-1-methyl-6-(4-hydroxyphenyl)imidazo(4,5-b)pyridine 2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE-2-14C N-(DEOXYGUANOSIN-8-YL)-2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE 2-AMINO-3-METHYL-6-PHENYLIMIDAZO(4,5-B)PYRIDINE 2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE-2 PHIP HYDROCHLORIDE

2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE

PHIP

5-b)pyridin-2-amine,1-methyl-6-phenyl-1h-imidazo(

Amino-1-methyl-6-phenylimidazo[4.5-b]pyridine

1H-Imidazo(4,5-B)pyridin-2-amine, 1-methyl-6-phenyl- (9ci)

1H-Imidazo(4,5-B)pyridine, 2-amino-1-methyl-6-phenyl-

Brn 5951264

Ccris 2954

Imidazo(4,5-B)pyridine, 2-amino-1-methyl-6-phenyl-

1-Methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-amine

2-AMINO-1-METHYL-6-PHENYLIMADAZO(4,5-B)PYRIDINE

2-AMINO-1-METHYL-6-PHENYL-1H-IMIDAZO[4,5-B]PYRIDINE

2-AMINO-1-METHYL-6-PHENOLIMIDAZO[4,5-B]PYRIDINE

2-Amino-1-methyl-6-phenylimidazo[4,5,b]pyridine, (PhIP)

1-Methyl-6-phenyl-1H-imidazo[4,5-β]pyridin-2-amine

2-Amino-1-methyl-6-phenylimidazo[4,5-β]pyridine

5-b)pyridine,2-amino-1-methyl-6-phenyl-1h-imidazo(

5-b)pyridine,2-amino-1-methyl-6-phenyl-imidazo(

1-Methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-amine 98%

2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, 2-Amino-1-methyl-6-phenyl-4-azabenzimidazole

1-Methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-amine98%

N,N-diethyl-3-hydroxy-4-methoxybenzamide

1H-Imidazo[4,5-b]pyridin-2-amine, 1-methyl-6-phenyl-

PhIP, 10 mM in DMSO

105650-23-5

C13H12N4

Detergents

Bases & Related Reagents

Mutagenesis Research Chemicals

Nucleotides