ChemicalBook > CAS DataBase List > 2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE

2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE

Product Name
2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE
CAS No.
105650-23-5
Chemical Name
2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE
Synonyms
PHIP;Ccris 2954;Brn 5951264;PhIP, 10 mM in DMSO;N,N-diethyl-3-hydroxy-4-methoxybenzamide;Amino-1-methyl-6-phenylimidazo[4.5-b]pyridine;2-AMINO-1-METHYL-6-PHENYLIMADAZO(4,5-B)PYRIDINE;2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE;2-AMINO-1-METHYL-6-PHENOLIMIDAZO[4,5-B]PYRIDINE;2-Amino-1-methyl-6-phenylimidazo[4,5-β]pyridine
CBNumber
CB4716839
Molecular Formula
C13H12N4
Formula Weight
224.26
MOL File
105650-23-5.mol
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2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE Property

Melting point:
300
Boiling point:
355.66°C (rough estimate)
Density 
1.2067 (rough estimate)
refractive index 
1.5890 (estimate)
storage temp. 
Refrigerator
solubility 
DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 15 mg/ml; Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml
form 
A crystalline solid
pka
7.72±0.30(Predicted)
color 
White to light yellow
biological source
synthetic
CAS DataBase Reference
105650-23-5(CAS DataBase Reference)
IARC
2B (Vol. 56) 1993
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Safety

Hazard Codes 
T
Hazard Note 
Toxic
HS Code 
29333999
Hazardous Substances Data
105650-23-5(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H331Toxic if inhaled

H335May cause respiratory irritation

H350May cause cancer

H360May damage fertility or the unborn child

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P311Call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
22590
Product name
2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
Purity
≥98%
Packaging
1mg
Price
$29
Updated
2024/03/01
Cayman Chemical
Product number
22590
Product name
2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
Purity
≥98%
Packaging
5mg
Price
$116
Updated
2024/03/01
Cayman Chemical
Product number
22590
Product name
2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
Purity
≥98%
Packaging
10mg
Price
$189
Updated
2024/03/01
Usbiological
Product number
131264
Product name
PHIP
Packaging
100ug
Price
$539
Updated
2021/12/16
Usbiological
Product number
298446
Product name
PHIP
Packaging
100ug
Price
$559
Updated
2021/12/16
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2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

Carcinogen

Definition

ChEBI: An imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, amino, and phenyl groups, respectively. It is the most abundant of the mutagenic heterocyclic amines found in coo ed meat and fish.

Biological Activity

Carcinogen developed in grilled meats. Induces breast and colon cancer in rats.

Safety Profile

Confirmed carcinogen with experimental carcinogenic data. Mutation data reported. When heated to decomposition it emits toxic vapors of NOx,.

Carcinogenicity

PhIP is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals and supporting genotoxicity data.

2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE Suppliers

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105650-23-5, 2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINERelated Search:


  • 2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE
  • PHIP
  • 5-b)pyridin-2-amine,1-methyl-6-phenyl-1h-imidazo(
  • Amino-1-methyl-6-phenylimidazo[4.5-b]pyridine
  • 1H-Imidazo(4,5-B)pyridin-2-amine, 1-methyl-6-phenyl- (9ci)
  • 1H-Imidazo(4,5-B)pyridine, 2-amino-1-methyl-6-phenyl-
  • Brn 5951264
  • Ccris 2954
  • Imidazo(4,5-B)pyridine, 2-amino-1-methyl-6-phenyl-
  • 1-Methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-amine
  • 2-AMINO-1-METHYL-6-PHENYLIMADAZO(4,5-B)PYRIDINE
  • 2-AMINO-1-METHYL-6-PHENYL-1H-IMIDAZO[4,5-B]PYRIDINE
  • 2-AMINO-1-METHYL-6-PHENOLIMIDAZO[4,5-B]PYRIDINE
  • 2-Amino-1-methyl-6-phenylimidazo[4,5,b]pyridine, (PhIP)
  • 1-Methyl-6-phenyl-1H-imidazo[4,5-β]pyridin-2-amine
  • 2-Amino-1-methyl-6-phenylimidazo[4,5-β]pyridine
  • 5-b)pyridine,2-amino-1-methyl-6-phenyl-1h-imidazo(
  • 5-b)pyridine,2-amino-1-methyl-6-phenyl-imidazo(
  • 1-Methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-amine 98%
  • 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, 2-Amino-1-methyl-6-phenyl-4-azabenzimidazole
  • 1-Methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-amine98%
  • N,N-diethyl-3-hydroxy-4-methoxybenzamide
  • 1H-Imidazo[4,5-b]pyridin-2-amine, 1-methyl-6-phenyl-
  • PhIP, 10 mM in DMSO
  • 105650-23-5
  • C13H12N4
  • Detergents
  • Bases & Related Reagents
  • Mutagenesis Research Chemicals
  • Nucleotides