macbecin I

Product Name: macbecin I
CAS No.: 73341-72-7
Chemical Name: macbecin I
Synonyms: Macbecin;macbecin I;(15R)-6,17-Didemethoxy-15-methoxy-6-methyl-11-O-methyl-geldanamycin;(6S,15R)-6,17-Didemethoxy-15-methoxy-6-methyl-11-O-methylgeldanamycin;Geldanamycin, 6,17-didemethoxy-15-methoxy-6-methyl-11-O-methyl-, (15R)-
CBNumber: CB11346962
Molecular Formula: C30H42N2O8
Formula Weight: 558.67
MOL File: 73341-72-7.mol

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macbecin I Property

Melting point:: 205-206 °C(Solv: ethanol (64-17-5); water (7732-18-5))
Boiling point:: 736.2±60.0 °C(Predicted)
Density: 1.17±0.1 g/cm3(Predicted)
storage temp.: Desiccate at -20°C
solubility: Soluble in DMSO > 10 mM
form: Powder
pka: 8.62±0.70(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 22225
Product name: Macbecin I
Purity: ≥95%
Packaging: 1mg
Price: $291
Updated: 2024/03/01

Tocris

Product number: 3061
Product name: MacbecinI
Packaging: 1
Price: $311
Updated: 2021/12/16

Usbiological

Product number: 255749
Product name: Macbecin I
Packaging: 1mg
Price: $573
Updated: 2021/12/16

TRC

Product number: M107525
Product name: MacbecinI
Packaging: 0.5mg
Price: $1200
Updated: 2021/12/16

ApexBio Technology

Product number: B7259
Product name: MacbecinI
Packaging: 1mg
Price: $465
Updated: 2021/12/16

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macbecin I Chemical Properties,Usage,Production

Uses

Macbecin I is an ansamycin antibiotic inhibitor of Hsp90 activity.

Biological Activity

Ansamycin antibiotic compound that inhibits Hsp90 activity (IC 50 = 2 μ M) by binding to the ATP-binding site. Exhibits antitumor and cytocidal activities (IC 50 ~ 0.4 μ M) by causing degradation of key oncogenic client proteins such as ErbB2 and cRaf1. Displays higher affinity and potency than geldanamycin (9,13-Dihydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-4,6,10,18,21-pentaene-3,20,22-trione, 9-carbamate ).

macbecin I Preparation Products And Raw materials

Raw materials

Preparation Products

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macbecin I Suppliers

CHINA 16 United Kingdom 1 United States 6 Global 23

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

MedBioPharmaceutical Technology Inc

Tel: 021-69568360 18916172912
Email: order@med-bio.cn
Country: China
ProdList: 8140
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24644
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11974
Advantage: 58

ApexBio Technology

Tel: --
Fax: --
Email: sales@apexbt.com
Country: United States
ProdList: 6251
Advantage: 58

73341-72-7, macbecin IRelated Search:

N-DECYL METHACRYLAMIDE macbecin I

macbecin I

(6S,15R)-6,17-Didemethoxy-15-methoxy-6-methyl-11-O-methylgeldanamycin

(15R)-6,17-Didemethoxy-15-methoxy-6-methyl-11-O-methyl-geldanamycin

Geldanamycin, 6,17-didemethoxy-15-methoxy-6-methyl-11-O-methyl-, (15R)-

Macbecin

73341-72-7