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cannabidiol dimethyl ether

Product Name
cannabidiol dimethyl ether
CAS No.
1242-67-7
Chemical Name
cannabidiol dimethyl ether
Synonyms
cannabidiol dimethyl ether;1-Methyl-3β-(2,6-dimethoxy-4-pentylphenyl)-4α-isopropenylcyclohexene;(3R)-1-Methyl-3β-(2,6-dimethoxy-4-pentylphenyl)-4α-isopropenyl-1-cyclohexene;(1R,6R)-1-(2,6-Dimethoxy-4-pentylphenyl)-3-methyl-6-isopropenyl-2-cyclohexene;Benzene, 1,3-dimethoxy-2-[(1R,6R)-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-5-pentyl-
CBNumber
CB11385417
Molecular Formula
C23H34O2
Formula Weight
342.51
MOL File
1242-67-7.mol
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cannabidiol dimethyl ether Property

Boiling point:
438.4±45.0 °C(Predicted)
Density 
0.957±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
≤14mg/ml in ethanol;1mg/ml in DMSO;2mg/ml in dimethyl formamide
form 
solution in acetate.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

H336May cause drowsiness or dizziness

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
13285
Product name
Cannabidiol dimethyl ether
Purity
≥98%
Packaging
1mg
Price
$56
Updated
2024/03/01
Cayman Chemical
Product number
13285
Product name
Cannabidiol dimethyl ether
Purity
≥98%
Packaging
5mg
Price
$179
Updated
2024/03/01
Cayman Chemical
Product number
13285
Product name
Cannabidiol dimethyl ether
Purity
≥98%
Packaging
10mg
Price
$200
Updated
2021/12/16
Cayman Chemical
Product number
13285
Product name
Cannabidiol dimethyl ether
Purity
≥98%
Packaging
50mg
Price
$875
Updated
2021/12/16
ApexBio Technology
Product number
C3420
Product name
Cannabidioldimethylether
Packaging
10mg(solution)
Price
$277
Updated
2021/12/16
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cannabidiol dimethyl ether Chemical Properties,Usage,Production

Uses

Lipoxygenases (LOs) are non-heme iron-containing dioxygenases that catalyze the oxidation of polyunsaturated fatty acids to generate unsaturated fatty acid hydroperoxides. The immediate products of 15-LO fatty acid oxidation act as mediators in inflammation, thrombosis, and cancer. CBDD is a cannabidiol derivative that potently and selectively inhibits 15-LO with an IC50 value of 0.28 μM. It does not inhibit 5-LO effectively (IC50 >200 μM).

Biological Activity

cannabidiol dimethyl ether (cbdd) is a cannabidiol derivative that potently and selectively inhibits 15-lox with an ic50 value of 0.28 μm.15-lox can oxygenate cholesterol esters in the low-density lipoprotein (ldl) particle. thus, 15-lox has been involved in the development of atherosclerosis, and cbdd may be a useful prototype for producing medicines for atherosclerosis [1].cbdd showed a potent inhibitory effect on the catalytic activity of cytochrome p450 2c19 with an ic50 value of 14.8 μμ [2]. cbdd inhibited the cyp2b6 activity with the ic50values of 75.7 μm [3]. cytochrome p450 enzymes have been isolated from numerous mammalian tissues such as liver, kidney, lung, intestine, adrenal cortex. cytochrome p450 enzymes have also existed in insects, plants, yeasts, and bacteria. cytochrome p450 has been known to catalyze hydroxylations, epoxidations, n-, s-, and o-dealkylations, n-oxidations, sulfoxidations, dehalogenations, and other reactions [4].

References

[1] takeda s, usami n, yamamoto i, et al. cannabidiol-2′, 6′-dimethyl ether, a cannabidiol derivative, is a highly potent and selective 15-lipoxygenase inhibitor[j]. drug metabolism and disposition, 2009, 37(8): 1733-1737.
[2] jiang r, yamaori s, okamoto y, et al. cannabidiol is a potent inhibitor of the catalytic activity of cytochrome p450 2c19[j]. drug metabolism and pharmacokinetics, 2013, 28(4): 332-338.
[3] yamaori s, maeda c, yamamoto i, et al. differential inhibition of human cytochrome p450 2a6 and 2b6 by major phytocannabinoids[j]. forensic toxicology, 2011, 29(2): 117-124.
[4] groves j t, han y z. models and mechanisms of cytochrome p450 action[m]//cytochrome p450. springer us, 1995: 3-48.

cannabidiol dimethyl ether Preparation Products And Raw materials

Raw materials

Preparation Products

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cannabidiol dimethyl ether Suppliers

BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
Advantage
65
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Shaanxi Dideu Medichem Co. Ltd
Tel
+86-29-81148696 +86-15536356810
Email
1022@dideu.com
Country
China
ProdList
3882
Advantage
58
ApexBio Technology
Tel
--
Fax
--
Email
sales@apexbt.com
Country
United States
ProdList
6251
Advantage
58
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View Lastest Price from cannabidiol dimethyl ether manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
cannabidiol dimethyl ether 1242-67-7
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000Kg
Release date
2024-08-08

1242-67-7, cannabidiol dimethyl etherRelated Search:


  • cannabidiol dimethyl ether
  • (1R,6R)-1-(2,6-Dimethoxy-4-pentylphenyl)-3-methyl-6-isopropenyl-2-cyclohexene
  • (3R)-1-Methyl-3β-(2,6-dimethoxy-4-pentylphenyl)-4α-isopropenyl-1-cyclohexene
  • 1-Methyl-3β-(2,6-dimethoxy-4-pentylphenyl)-4α-isopropenylcyclohexene
  • Benzene, 1,3-dimethoxy-2-[(1R,6R)-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-5-pentyl-
  • 1242-67-7