2-AMINO-3-(METHYLAMINO)PYRAZINE

Product Name: 2-AMINO-3-(METHYLAMINO)PYRAZINE
CAS No.: 84996-40-7
Chemical Name: 2-AMINO-3-(METHYLAMINO)PYRAZINE
Synonyms: N2-methylpyrazine-2,3-diamin;N-METHYLPYRAZINE-2,3-DIAMINE;N2-methylpyrazine-2,3-diamine;2,3-Pyrazinediamine, N2-methyl-;2-AMINO-3-(METHYLAMINO)PYRAZINE
CBNumber: CB1138793
Molecular Formula: C5H8N4
Formula Weight: 124.14
MOL File: 84996-40-7.mol

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2-AMINO-3-(METHYLAMINO)PYRAZINE Property

storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
Appearance: Yellow to brown Solid

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: A578080
Product name: 2-Amino-3-(methylamino)pyrazine
Packaging: 100mg
Price: $65
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA154142
Product name: 2-Amino-3-(methylamino)pyrazine
Packaging: 250mg
Price: $95
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA154142
Product name: 2-Amino-3-(methylamino)pyrazine
Packaging: 500mg
Price: $165
Updated: 2021/12/16

Matrix Scientific

Product number: 118862
Product name: 2-Amino-3-(methylamino)pyrazine
Purity: 95+%
Packaging: 250mg
Price: $180
Updated: 2021/12/16

AK Scientific

Product number: Y6424
Product name: N2-Methylpyrazine-2,3-diamine
Packaging: 1g
Price: $211
Updated: 2021/12/16

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2-AMINO-3-(METHYLAMINO)PYRAZINE Chemical Properties,Usage,Production

Synthesis

6863-73-6

74-89-5

84996-40-7

General procedure for the synthesis of 2-amino-3-methylaminopyrazine from 2-amino-3-chloropyrazine (5.20 g, 40.1 mmol) and monomethylamine: 2-amino-3-chloropyrazine (5.20 g, 40.1 mmol) and CuSO4 (640 mg, 4.01 mmol) in 12 M aqueous methylamine solution (40.0 mL, 480 mmol) were The mixture was placed in a microwave reactor and the reaction was stirred at 120 °C for 3 hours. Upon completion of the reaction, the reaction mixture was cooled to room temperature and concentrated under reduced pressure to remove the solvent. The residue was purified by fast column chromatography (silica gel as stationary phase and chloroform solution with 0-5% methanol as eluent) to afford the target product 2-amino-3-methylaminopyrazine (3.99 g, 80% yield) as a yellow solid. The structure of the product was confirmed by 1H NMR (DMSO-d6) and mass spectrometry (ESI): 1H NMR (DMSO-d6) δ 2.81 (d, 3H, J=4.7 Hz), 5.84 (s, 2H), 6.13 (q, 1H, J=4.7 Hz), 7.09 (d, 1H, J=3.1 Hz), 7.23 (d, 1H, J=3.1 Hz ); MS (ESI) m/z 125 [M+H]+.

References

[1] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 13, p. 3515 - 3526

2-AMINO-3-(METHYLAMINO)PYRAZINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMINO-3-(METHYLAMINO)PYRAZINE Suppliers

China 36 Czech Republic 1 Germany 1 Hungary 1 India 1 United Kingdom 2 United States 5 Global 47

Pure Chemistry Scientific Inc.

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84996-40-7, 2-AMINO-3-(METHYLAMINO)PYRAZINERelated Search:

Aminopyrazine TIMTEC-BB SBB006492 N-1,3-BENZODIOXOL-5-YL-6-(4-METHYLPIPERIDIN-1-YL)[1,2,5]OXADIAZOLO[3,4-B]PYRAZIN-5-AMINE 2-([6-(4-CHLOROANILINO)[1,2,5]OXADIAZOLO[3,4-B]PYRAZIN-5-YL]AMINO)-1-ETHANOL 4,11-DIHYDRO[1,2,5]OXADIAZOLO[3',4':5,6]PYRAZINO[2,3-B]QUINOXALINE N-[6-(4-FLUOROANILINO)[1,2,5]OXADIAZOLO[3,4-B]PYRAZIN-5-YL]-N-(4-FLUOROPHENYL)AMINE ZERENEX E/6022362 N,N'-BIS(2-METHOXYPHENYL)QUINOXALINE-2,3-DIAMINE N-(BENZO[D][1,3]DIOXOL-5-YL)-6-(4-BENZYLPIPERIDIN-1-YL)-[1,2,5]OXADIAZOLO[3,4-B]PYRAZIN-5-AMINE AURORA 12630 N-[3-(4-fluoroanilino)-2-quinoxalinyl]-N-(4-fluorophenyl)amine N-(6-AMINO[1,2,5]OXADIAZOLO[3,4-B]PYRAZIN-5-YL)-N-(2-FLUOROPHENYL)AMINE N,N'-dimethylquinoxaline-2,3-diamine AURORA 12631 N-[6-(2-FLUOROANILINO)[1,2,5]OXADIAZOLO[3,4-B]PYRAZIN-5-YL]-N-(2-FLUOROPHENYL)AMINE 6,12-DIHYDRO[1,2,5]OXADIAZOLO[3',4':5,6]PYRAZINO[2,3-B][1,2,5]THIADIAZOLO[3,4-F]QUINOXALINE 2,3-DIANILINO-6-NITROQUINOXALINE AURORA 14733

N-METHYLPYRAZINE-2,3-DIAMINE

N2-methylpyrazine-2,3-diamine

2-AMINO-3-(METHYLAMINO)PYRAZINE

2,3-Pyrazinediamine, N2-methyl-

N2-methylpyrazine-2,3-diamin

84996-40-7