8-[2-(3-Chlorophenyl)ethenyl]-3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione

Product Name: 8-[2-(3-Chlorophenyl)ethenyl]-3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
CAS No.: 148589-13-3
Chemical Name: 8-[2-(3-Chlorophenyl)ethenyl]-3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
Synonyms: 8CSC;8-CSC;8 CSC;1H-Purine-2,6-dione, 8-[2-(3-chlorophenyl)ethenyl]-3,7-dihydro-1,3,7-trimethyl-
CBNumber: CB11392080
Molecular Formula: C16H15ClN4O2
Formula Weight: 330.77
MOL File: 148589-13-3.mol

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8-[2-(3-Chlorophenyl)ethenyl]-3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione Chemical Properties,Usage,Production

Uses

8-(3-Chlorostyryl)caffeine (CSC) is an adenosine antagonist with selective activity at the A2a adenosine receptor. 8-(3-Chlorostyryl)caffeine showed 520-fold selectivity in radioligand binding experiments in rat brain. Antagonism of adenylylase by 8-(3-Chlorostyryl)caffeine shows 22-fold selectivity in rat chromaffin cells When 8-(3-Chlorostyryl)caffeine is co-administered with the A1-selective antagonist CPX, It can also further increase exercise activity. 8-(3-Chlorostyryl)caffeine exhibits good MAO-B inhibitory activity in primate mitochondria. 8-(3-Chlorostyryl)caffeine also has excellent A2A receptor affinity[1].

Definition

ChEBI: 8-(3-chlorostyryl)caffeine is caffeine substituted at its 8-position by an (E)-3-chlorostyryl group. It has a role as an adenosine A2A receptor antagonist and an EC 1.4.3.4 (monoamine oxidase) inhibitor. It is a trimethylxanthine and a member of monochlorobenzenes. It is functionally related to a caffeine.

References

[1] 8-(3-Chlorostyryl)caffeine (CSC) is a selective A2-adenosine antagonist in vitro and in vivo

8-[2-(3-Chlorophenyl)ethenyl]-3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione Preparation Products And Raw materials

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8-[2-(3-Chlorophenyl)ethenyl]-3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione Suppliers

China 1 South Korea 1 United States 2 Global 4

TargetMol Chemicals Inc.

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TargetMol Chemicals Inc.

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TargetMol Chemicals Inc.

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148589-13-3, 8-[2-(3-Chlorophenyl)ethenyl]-3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dioneRelated Search:

8-[2-(3-Chlorophenyl)ethenyl]-3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione 1,9-DIMETHYLXANTHINE ISOCAFFEINE 1H-Imidazole-4-carboxamide,5-amino-2-methyl-(9CI) 2-STYRYL-1H-IMIDAZOLE 4-Amino-5-imidazolecarboxamide hydrochloride 2,6-DIHYDROXY-3,9-DIMETHYLPURINE 8-METHYLXANTHINE 4-AMINO-5-IMIDAZOLECARBOXAMIDE 9-METHYLXANTHINE

1H-Purine-2,6-dione, 8-[2-(3-chlorophenyl)ethenyl]-3,7-dihydro-1,3,7-trimethyl-

8 CSC

8CSC

8-CSC

148589-13-3