elaiophylin
- Product Name
- elaiophylin
- CAS No.
- 37318-06-2
- Chemical Name
- elaiophylin
- Synonyms
- EfoMycin E;Salbomycin;Elaiophilin;elaiophylin;GopalaMicin;EfoMycine E;Azalomycin B;Olive leaf hormone;Elaiophylin (Azalomycin B);255-E, 5001B, 56-62, 846 I, SNA 4606-3, AzaloMycin B, GopalaMicin, SalboMycin
- CBNumber
- CB11393845
- Molecular Formula
- C54H88O18
- Formula Weight
- 1025.27
- MOL File
- 37318-06-2.mol
elaiophylin Property
- Melting point:
- 179-182℃
- Boiling point:
- 1080.5±65.0 °C(Predicted)
- Density
- 1.25
- storage temp.
- -20°C Freezer
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 12.18±0.70(Predicted)
- form
- White to off-white solid.
- color
- White to Off-White
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 15583
- Product name
- Elaiophylin
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $110
- Updated
- 2024/03/01
- Product number
- 15583
- Product name
- Elaiophylin
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $326
- Updated
- 2024/03/01
- Product number
- 207162
- Product name
- Elaiophylin
- Packaging
- 1mg
- Price
- $325
- Updated
- 2021/12/16
- Product number
- E501003
- Product name
- Elaiophylin
- Packaging
- 2.5mg
- Price
- $525
- Updated
- 2021/12/16
- Product number
- BVT-0185-M001
- Product name
- Elaiophylin
- Purity
- ≥95%(HPLC)
- Packaging
- 1mg
- Price
- $90
- Updated
- 2021/12/16
elaiophylin Chemical Properties,Usage,Production
Uses
Elaiophyllin is a highly characteristic metabolite produced by Streptomyces hygroscopicus. Elaiophylin inhibits testosterone 5-reductase. Elaiophylin is synergistic with its co-metabolite, rapamycin, as an antifungal. Elaiophylin also has anthelminthic and immunosuppressive activity and inhibits NO synthesis. Elaiophylin displays broad, albeit weak, biological activity against bacteria, nematodes, protozoa and mammalian tumour cells.
Uses
Elaiophylin is a highly characteristic metabolite produced by Streptomyces hygroscopicus. Elaiophylin inhibits testosterone 5-reductase. Elaiophylin is synergistic with its co-metabolite, rapamycin, as an antifungal. Elaiophylin also has anthelmintic and immunosuppressive activity and inhibits NO synthesis. Elaiophylin displays broad, albeit weak, biological activity against bacteria, nematodes, protozoa and mammalian tumor cells.
Uses
Elaiophylin is a macrodiolide antibiotic that can be isolated from various strains of Streptomyces. It displays in vitro anti-protozoal activity against both Plasmodium and Trypanosoma (IC50s = 370 and 460 ng/ml, respectively) and cytotoxicity against human fetal lung fibroblast MRC-5 cells (IC50 = 870 ng/ml). Elaiophylin alone has no activity against Candida, although it enhances the anti-fungal activity of rapamycin . Elaiophylin also forms stable, long-lasting ion channels in bilayer membranes that are selective for cations.
Definition
ChEBI: A macrolide that is isolated from several bacteria including Streptomyces violaceoniger and other soil actinomycetes.