3-BROMO-4-TERT-BUTYLBENZOICACID
- Product Name
- 3-BROMO-4-TERT-BUTYLBENZOICACID
- CAS No.
- 38473-89-1
- Chemical Name
- 3-BROMO-4-TERT-BUTYLBENZOICACID
- Synonyms
- 3-Bromo-4-(tert-butyl);3-BROMO-4-TERT-BUTYLBENZOICACID;3-BroMo-4-tert-butylbenzoicbacid;3-Bromo-4-(1,1-dimethylethyl)-benzoic acid;Benzoic acid, 3-bromo-4-(1,1-dimethylethyl)-
- CBNumber
- CB11415167
- Molecular Formula
- C11H13BrO2
- Formula Weight
- 257.12
- MOL File
- 38473-89-1.mol
3-BROMO-4-TERT-BUTYLBENZOICACID Property
- Melting point:
- 176.5 °C
- Boiling point:
- 327.7±35.0 °C(Predicted)
- Density
- 1.391±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 4.01±0.10(Predicted)
Safety
- HS Code
- 2916399090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- FB148231
- Product name
- 3-Bromo-4-tert-butylbenzoicacid
- Packaging
- 50mg
- Price
- $124
- Updated
- 2021/12/16
- Product number
- 4984AB
- Product name
- 3-Bromo-4-(tert-butyl)benzoicacid
- Packaging
- 25mg
- Price
- $145
- Updated
- 2021/12/16
- Product number
- FB148231
- Product name
- 3-Bromo-4-tert-butylbenzoicacid
- Packaging
- 100mg
- Price
- $215
- Updated
- 2021/12/16
- Product number
- FB148231
- Product name
- 3-Bromo-4-tert-butylbenzoicacid
- Packaging
- 25mg
- Price
- $71
- Updated
- 2021/12/16
- Product number
- FB148231
- Product name
- 3-Bromo-4-tert-butylbenzoicacid
- Packaging
- 250mg
- Price
- $430
- Updated
- 2021/12/16
3-BROMO-4-TERT-BUTYLBENZOICACID Chemical Properties,Usage,Production
Synthesis
98-73-7
38473-89-1
4-tert-butylbenzoic acid (500 mg, 2.8 mmol) was dissolved in acetic acid (11 mL), nitric acid (1.7 mL) and bromine (114 μL, 5.9 mmol) were added with rapid stirring. Subsequently, a solution of silver nitrate (1.01 g, 5.9 mmol) in water (5 mL) was slowly added to the reaction system, at which point a thick yellow precipitate was observed to form. After addition of additional acetic acid (2 mL), the reaction mixture was heated to reflux for 1 hour. Upon completion of the reaction, the reaction solution was filtered while hot and water was added dropwise to the filtrate until a white solid precipitated. The solid was collected, air dried and purified by recrystallization from acetic acid to give finally 3-bromo-4-tert-butylbenzoic acid as a white solid (263 mg, 36% yield). The product was characterized by 1H NMR (CDCl3, 300 MHz): δ 1.85 (s, 9H, (CH3)3), 7.86 (d, 1H, J = 8.5 Hz, ArH), 8.26 (dd, 1H, J = 2.0, 8.5 Hz, ArH), 8.62 (d, 1H, J = 2.0 Hz, ArH).
References
[1] Patent: WO2012/4567, 2012, A2. Location in patent: Page/Page column 91
[2] Australian Journal of Chemistry, 1990, vol. 43, # 5, p. 807 - 814
[3] Patent: WO2010/142956, 2010, A2. Location in patent: Page/Page column 28-29
[4] Journal of the Chemical Society, 1958, p. 120,126
[5] Journal of the Chemical Society, 1958, p. 120,126
3-BROMO-4-TERT-BUTYLBENZOICACID Preparation Products And Raw materials
Raw materials
Preparation Products
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