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PERAKINE

Product Name
PERAKINE
CAS No.
4382-56-3
Chemical Name
PERAKINE
Synonyms
PERAKINE;Aids003043;Aids-003043;Raucaffrine;Indole alkaloid;(17R,20α)-19-Oxo-1,2-didehydro-1-demethyl-21β-methyl-18-norajmalan-17-ol acetate;18-Norajmalan-19-al, 17-(acetyloxy)-1,2-didehydro-1-demethyl-21-methyl-, (17R,20α,21β)-;18-Norajmalan-19-al, 17-(acetyloxy)-1,2-didehydro-1-demethyl-21-methyl-, (17R,20A,21B)-;(13R)-13-Acetyloxy-7aα,2α,6α-ethan[1]yl[2]ylidene-1,2,3,4,6,7,7a,12bβ-octahydro-4α-methylindolo[2,3-a]quinolizine-3β-carbaldehyde
CBNumber
CB11439626
Molecular Formula
C21H22N2O3
Formula Weight
350.42
MOL File
4382-56-3.mol
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PERAKINE Property

Melting point:
186 °C
Boiling point:
492.8±45.0 °C(Predicted)
Density 
1.59±0.1 g/cm3(Predicted)
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Powder
pka
5.38±0.70(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Usbiological
Product number
300770
Product name
Perakine
Packaging
10mg
Price
$490
Updated
2021/12/16
Biorbyt Ltd
Product number
orb105275
Product name
Perakine
Purity
>98%,Standard References Grade
Packaging
20mg
Price
$569.5
Updated
2021/12/16
Biorbyt Ltd
Product number
orb594184
Product name
Perakine
Packaging
5mg
Price
$596.7
Updated
2021/12/16
Biorbyt Ltd
Product number
orb594184
Product name
Perakine
Packaging
10mg
Price
$799
Updated
2021/12/16
DC Chemicals
Product number
DCP-015
Product name
Perakine
Purity
>98%,StandardReferencesGrade
Packaging
20mg
Price
$280
Updated
2021/12/16
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PERAKINE Chemical Properties,Usage,Production

Description

This alkaloid has been shown to be identical with Perakine (q.v.).

Uses

Perakine is an alkaloid extracted from family of Rauvolfia plants which acts as an inhibitor of aldose reductase, a potent drug target for diabetes.

Definition

ChEBI: An indole alkaloid having a ajmalan-type skeleton and characterised by a 17alpha-acetoxy group, a 21beta-methyl group, loss of the 1-methyl group with associated unsaturation at N(1)2C(2), and a 20alph -formyl group in place of the 20beta-ethyl side-chain.

References

Khan, Khan, Siddiqui., Pakistan 1. Sci. Ind. Res., 8, 23 (1965)

PERAKINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from PERAKINE manufacturers

Career Henan Chemical Co
Product
PERAKINE 4382-56-3
Price
US $1.00/kg
Min. Order
1g
Purity
99%
Supply Ability
100KG
Release date
2018-12-24

4382-56-3, PERAKINERelated Search:

menisdaurin L-Hyoscyamine Xanthiazone VERATRIDINE daurisoline 2-[2-(Methylamino)benzoyl]-3,4-dihydro-β-carboline-1(2H)-one Xanthiside veratramine Daurinoline VERATRINE Ajmaline

  • PERAKINE
  • (13R)-13-Acetyloxy-7aα,2α,6α-ethan[1]yl[2]ylidene-1,2,3,4,6,7,7a,12bβ-octahydro-4α-methylindolo[2,3-a]quinolizine-3β-carbaldehyde
  • (17R,20α)-19-Oxo-1,2-didehydro-1-demethyl-21β-methyl-18-norajmalan-17-ol acetate
  • 18-Norajmalan-19-al, 17-(acetyloxy)-1,2-didehydro-1-demethyl-21-methyl-, (17R,20A,21B)-
  • Aids003043
  • Aids-003043
  • Indole alkaloid
  • Raucaffrine
  • 18-Norajmalan-19-al, 17-(acetyloxy)-1,2-didehydro-1-demethyl-21-methyl-, (17R,20α,21β)-
  • 4382-56-3