(R)-N-BOC-4-FLUOROPHENYLGLYCINE

Product Name: (R)-N-BOC-4-FLUOROPHENYLGLYCINE
CAS No.: 196707-32-1
Chemical Name: (R)-N-BOC-4-FLUOROPHENYLGLYCINE
Synonyms: Boc-D-4-Fluorophenylglycine;BOC-4-FLUORO-D-PHENYLGLYCINE;N-Boc-R-4-Fluorophenylglycine;(R)-N-BOC-4-FLUOROPHENYLGLYCINE;(R)-N-Boc-2-(4-fluorophenyl)glycine;(R)-N-boc-4-Fluorophenylglycine(e.e.);(R)-N-BOC-4-Fluorophenylglycine, 98% ee;(R)-N-BOC-4-FLUOROPHENYLGLYCINE USP/EP/BP;Boc-(R)-2-amino-2-(4-fluorophenyl)acetic acid;(R)-N-Boc-4-fluorophenylglycine, 95%, ee:98%
CBNumber: CB1145270
Molecular Formula: C13H16FNO4
Formula Weight: 269.27
MOL File: 196707-32-1.mol

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(R)-N-BOC-4-FLUOROPHENYLGLYCINE Property

Melting point:: 85.7 °C
Boiling point:: 408.4±40.0 °C(Predicted)
Density: 1.2168 (estimate)
storage temp.: Sealed in dry,Room Temperature
form: Powder
pka: 3.47±0.10(Predicted)
color: White
CAS DataBase Reference: 196707-32-1

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Safety

Safety Statements: 24/25
HazardClass: IRRITANT
HS Code: 29224985

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Activate Scientific

Product number: AS89135
Product name: (R)-N-Boc-4-fluorophenylglycine
Purity: 95% ee
Packaging: 1g
Price: $205
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: AAA0000109
Product name: (R)-N-BOC-4-FLUORO PHENYLGLYCINE
Purity: 95.00%
Packaging: 1G
Price: $664.78
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: AAA0000109
Product name: (R)-N-BOC-4-FLUORO PHENYLGLYCINE
Purity: 95.00%
Packaging: 5G
Price: $3467.31
Updated: 2021/12/16

Acrotein

Product number: A-5664
Product name: Boc-(R)-2-amino-2-(4-fluorophenyl)aceticacid
Purity: 97%
Packaging: 1g
Price: $137.5
Updated: 2021/12/16

Alichem

Product number: 196707321
Product name: (R)-2-((tert-Butoxycarbonyl)amino)-2-(4-fluorophenyl)aceticacid
Packaging: 250mg
Price: $183.6
Updated: 2021/12/16

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(R)-N-BOC-4-FLUOROPHENYLGLYCINE Chemical Properties,Usage,Production

Chemical Properties

white powder

Synthesis

24424-99-5

351-95-1

196707-32-1

Example 59a Single Enantiomeric Isomer; R Configuration NaHCO3 (1.0 g, 11.9 mmol) was added to a stirred aqueous suspension of (R)-4-fluorophenylglycine (1.0 g, 5.9 mmol). after 30 min, a solution of di-tert-butyl dicarbonate (1.5 g, 7.1 mmol) dissolved in tertiary butanol was slowly added dropwise. The reaction mixture was stirred overnight at room temperature. Upon completion of the reaction, the reaction mixture was diluted with water and the pH was subsequently adjusted to 4-5 with 5% aqueous citric acid.The mixture was extracted with dichloromethane (DCM), the organic layer was separated, dried over anhydrous Na2SO4 and concentrated under reduced pressure to give the title compound (R)-2-((tert-butoxycarbonyl)amino)-2-(4-fluorophenyl)acetic acid (1.6 g). HPLC-MS (Method 17): retention time (Rt) = 2.25 min; mass spectrum (ES+): m/z = 292 [M + Na]+.

References

[1] Patent: US2015/105397, 2015, A1. Location in patent: Paragraph 0385; 0386; 0387; 0388; 0389

(R)-N-BOC-4-FLUOROPHENYLGLYCINE Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-N-BOC-4-FLUOROPHENYLGLYCINE Suppliers

Belgium 1 China 34 Germany 1 United Kingdom 1 United States 8 Global 45

Meryer (Shanghai) Chemical Technology Co., Ltd.

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Wuhan Chemwish Technology Co., Ltd

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Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
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Maya High Purity Chemicals

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Thermo Fisher Scientific

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Beijing innoChem Science & Technology Co.,Ltd.

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9ding chemical ( Shanghai) Limited

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Shanghai Aladdin Bio-Chem Technology Co.,LTD

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LABTER PHARMATECH(BEIJING) CO.,LTD

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Shanghai GL Peptide Ltd.

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196707-32-1, (R)-N-BOC-4-FLUOROPHENYLGLYCINERelated Search:

TERT-BUTOXYCARBONYLAMINO-PHENYL-ACETIC ACID N-BOC-D/L-PHENYLGLYCINOL (S)-N-BOC-4-FLUOROPHENYLGLYCINE 4-Fluorophenylacetic acid 4-Fluorophenylglycine (R)-4-Fluorophenylglycine BOC-D-PHG-OH (R)-N-(tert-Butoxycarbonyl)-2-phenylglycinol (S)-1-(4-FLUOROPHENYL)ETHYLAMINE FOR-D-PHG-OH N-ME-D-PHG-OH (S) (-)-ALPHA-PHENETHYLURETHANE N-BOC-2-FLUOROPHENYLGLYCINE N-BOC- 4-FLUOROPHENYLGLYCINE (R)-N-BOC-4-FLUOROPHENYLGLYCINE (S)-N-METHYL-1-(4-FLUOROPHENYL)ETHYLAMINE (R)-TERT-BUTOXYCARBONYLAMINO-(3,4-DIFLUORO-PHENYL)-ACETIC ACID (R)-TERT-BUTOXYCARBONYLAMINO-(2,4-DIFLUORO-PHENYL)-ACETIC ACID

(D)-N-TERT-BUTOXYCARBONYL-ALPHA-(4-FLUOROPHENYL)ACETIC ACID

BOC-4-FLUORO-D-PHENYLGLYCINE

(R)-N-boc-4-Fluorophenylglycine(e.e.)

(R)-N-BOC-4-FLUOROPHENYLGLYCINE 95% (98% E.E.)

(R)-N-Boc-4-fluorophenylglycine, 95%, ee:98%

(R)-N-BOC-4-Fluorophenylglycine, 98% ee

(R)-N-BOC-4-Fluorophenylglycine, 98% ee, 95% 1GR

Boc-(R)-2-amino-2-(4-fluorophenyl)acetic acid

(R)-N-BOC-4-FLUOROPHENYLGLYCINE

(R)-TERT-BUTOXYCARBONYLAMINO-(4-FLUORO-PHENYL)-ACETIC ACID

N-Boc-R-4-Fluorophenylglycine

Benzeneacetic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]-4-fluoro-, (αR)-

(2R)-2-(4-fluorophenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]acetate

(R)-N-BOC-4-FLUOROPHENYLGLYCINE USP/EP/BP

(R)-2-((tert-Butoxycarbonyl)amino)-2-(4-fluorophenyl)acetic acid

Boc-D-4-Fluorophenylglycine

(R)-N-Boc-2-(4-fluorophenyl)glycine

(2R)-2-(4-fluorophenyl)-2-[(2-methylpropan-2-yl)oxycarbon

(2R)-2-(tert-butoxycarbonylamino)-2-(4-fluorophenyl)acetic acid

196707-32-1