Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate
- Product Name
- Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate
- CAS No.
- 184177-81-9
- Chemical Name
- Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate
- Synonyms
- Posaconazole SM2;Posaconazole Impurity 14;Posaconazole Impurity 56;Intermediate of Posaconazole;piperazin-1-yl)phenylcarbamate;Phenyl (4-(4-(4-hydroxyphenyl);Posaconazole Hydroxy Carbamate Impurity;Posaconazole Diastereoisomer 3 (S,R,R,R);4-(4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL)PHENYL CARBAMATE;PHENYL {4-[4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL]PHENYL}CARBAMATE
- CBNumber
- CB11476162
- Molecular Formula
- C23H23N3O3
- Formula Weight
- 389.45
- MOL File
- 184177-81-9.mol
Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate Property
- Boiling point:
- 603.9±55.0 °C(Predicted)
- Density
- 1.296
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 12.18±0.30(Predicted)
- InChI
- InChI=1S/C23H23N3O3/c27-21-12-10-20(11-13-21)26-16-14-25(15-17-26)19-8-6-18(7-9-19)24-23(28)29-22-4-2-1-3-5-22/h1-13,27H,14-17H2,(H,24,28)
- InChIKey
- IKRKMYDCUZYKHX-UHFFFAOYSA-N
- SMILES
- C(OC1=CC=CC=C1)(=O)NC1=CC=C(N2CCN(C3=CC=C(O)C=C3)CC2)C=C1
- CAS DataBase Reference
- 184177-81-9
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P273Avoid release to the environment.
P391Collect spillage. Hazardous to the aquatic environment
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- H950215
- Product name
- [4-[4-(4-Hydroxyphenyl)-1-piperazinyl]phenyl]carbamicAcidPhenylEster
- Packaging
- 1g
- Price
- $635
- Updated
- 2021/12/16
- Product number
- 090772
- Product name
- Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate
- Purity
- 95+%
- Packaging
- 1g
- Price
- $1143
- Updated
- 2021/12/16
- Product number
- W3988
- Product name
- Phenyl(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate
- Packaging
- 1g
- Price
- $70
- Updated
- 2021/12/16
- Product number
- W3988
- Product name
- Phenyl(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate
- Packaging
- 25g
- Price
- $163
- Updated
- 2021/12/16
- Product number
- CHM0393749
- Product name
- PHENYL-(4-(4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL)PHENYL)CARBAMATE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $498.82
- Updated
- 2021/12/16
Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate Chemical Properties,Usage,Production
Description
Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate is a piperazine derivative that inhibits the growth of gram-positive bacteria.Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate is a carbamic acid that binds to the 50S ribosomal subunit of bacteria, preventing transcription and replication. Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)) carbamate is a carbamic acid that binds to the 50S ribosomal subunit of bacteria, preventing transcription and replication. Human activity on human erythrocytes using the membrane clamp technique is frequent. This active form is metabolised by a number of metabolic transformations including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or binding to glucuronic acid.
Uses
PHENYL {4-[4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL]PHENYL}CARBAMATE is a carboxylic acid ester organic substance and can be used as a pharmaceutical intermediate.
Uses
[4-[4-(4-Hydroxyphenyl)-1-piperazinyl]phenyl]carbamic Acid Phenyl Ester is an impurity of Posaconazole (P689600), which is orally active antifungal triazole.
Definition
ChEBI: N-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]carbamic acid phenyl ester is a member of piperazines.
Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate Preparation Products And Raw materials
Raw materials
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View Lastest Price from Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate manufacturers
- Product
- PHENYL (4-(4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL)PHENYL)CARBAMATE 184177-81-9
- Price
- US $0.00/kg
- Min. Order
- 25kg
- Purity
- 98%
- Supply Ability
- Inquiry
- Release date
- 2022-11-02
- Product
- Posaconazole Intermediate 184177-81-9
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%min
- Supply Ability
- 500kgs
- Release date
- 2021-10-18
- Product
- [4-[4-(4-Hydroxyphenyl)-1-piperazinyl]phenyl]carbamic acid phenyl ester 184177-81-9
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99%min
- Supply Ability
- 100kg ; 500kg
- Release date
- 2023-06-16