ChemicalBook > CAS DataBase List > Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate

Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate

Product Name
Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate
CAS No.
184177-81-9
Chemical Name
Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate
Synonyms
Posaconazole SM2;Posaconazole Impurity 14;Posaconazole Impurity 56;Intermediate of Posaconazole;piperazin-1-yl)phenylcarbamate;Phenyl (4-(4-(4-hydroxyphenyl);Posaconazole Hydroxy Carbamate Impurity;Posaconazole Diastereoisomer 3 (S,R,R,R);4-(4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL)PHENYL CARBAMATE;PHENYL {4-[4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL]PHENYL}CARBAMATE
CBNumber
CB11476162
Molecular Formula
C23H23N3O3
Formula Weight
389.45
MOL File
184177-81-9.mol
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Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate Property

Boiling point:
603.9±55.0 °C(Predicted)
Density 
1.296
storage temp. 
Sealed in dry,Room Temperature
pka
12.18±0.30(Predicted)
InChI
InChI=1S/C23H23N3O3/c27-21-12-10-20(11-13-21)26-16-14-25(15-17-26)19-8-6-18(7-9-19)24-23(28)29-22-4-2-1-3-5-22/h1-13,27H,14-17H2,(H,24,28)
InChIKey
IKRKMYDCUZYKHX-UHFFFAOYSA-N
SMILES
C(OC1=CC=CC=C1)(=O)NC1=CC=C(N2CCN(C3=CC=C(O)C=C3)CC2)C=C1
CAS DataBase Reference
184177-81-9
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
H950215
Product name
[4-[4-(4-Hydroxyphenyl)-1-piperazinyl]phenyl]carbamicAcidPhenylEster
Packaging
1g
Price
$635
Updated
2021/12/16
Matrix Scientific
Product number
090772
Product name
Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate
Purity
95+%
Packaging
1g
Price
$1143
Updated
2021/12/16
AK Scientific
Product number
W3988
Product name
Phenyl(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate
Packaging
1g
Price
$70
Updated
2021/12/16
AK Scientific
Product number
W3988
Product name
Phenyl(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate
Packaging
25g
Price
$163
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0393749
Product name
PHENYL-(4-(4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL)PHENYL)CARBAMATE
Purity
95.00%
Packaging
5MG
Price
$498.82
Updated
2021/12/16
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Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate Chemical Properties,Usage,Production

Description

Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate is a piperazine derivative that inhibits the growth of gram-positive bacteria.Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate is a carbamic acid that binds to the 50S ribosomal subunit of bacteria, preventing transcription and replication. Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)) carbamate is a carbamic acid that binds to the 50S ribosomal subunit of bacteria, preventing transcription and replication. Human activity on human erythrocytes using the membrane clamp technique is frequent. This active form is metabolised by a number of metabolic transformations including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or binding to glucuronic acid.

Uses

PHENYL {4-[4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL]PHENYL}CARBAMATE is a carboxylic acid ester organic substance and can be used as a pharmaceutical intermediate.

Uses

[4-[4-(4-Hydroxyphenyl)-1-piperazinyl]phenyl]carbamic Acid Phenyl Ester is an impurity of Posaconazole (P689600), which is orally active antifungal triazole.

Definition

ChEBI: N-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]carbamic acid phenyl ester is a member of piperazines.

Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate Preparation Products And Raw materials

Raw materials

Preparation Products

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Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate Suppliers

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View Lastest Price from Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Posaconazole Intermediate 184177-81-9
Price
US $0.00/KG
Min. Order
1KG
Purity
99%min
Supply Ability
500kgs
Release date
2021-10-18
ShenZhen H&D Pharmaceutical Technology Co., LTD
Product
Posaconazole Impurity 29 184177-81-9
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
98%
Supply Ability
500mg
Release date
2024-06-28
Shaanxi Dideu New Materials Co. Ltd
Product
[4-[4-(4-Hydroxyphenyl)-1-piperazinyl]phenyl]carbamic acid phenyl ester 184177-81-9
Price
US $0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
10000KGS
Release date
2024-11-15

184177-81-9, Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamateRelated Search:

4-Methoxyphenol Posaconazole Impurity 44 (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester Posaconazole Impurity 51 D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxyMethyl)-1-(1H-1,2,4-triazol-1-yl)- 4-([4-(4-METHYLOXY-PHENYL)-PIPERAZIN-1-YL]-PHENYL)-CARBAMIC ACID PHENYL ESTER 1-(4-Methoxyphenyl)-4-(4-nitrophenyl)piperazine Posaconazole Impurity 47 Posaconazole Impurity 42 1-(((2R,4R)-4-((Benzyloxy)methyl)-2-(2,4-difluorophenyl)tetrahydrofuran-2-yl)methyl)-1H-1,2,4-triazole 1,3-PROPANEDIOL, 2-[2-(2,4-DIFLUOROPHENYL)-2-PROPEN-1-YL]- 1-(4-Methoxyphenyl)piperazine Posaconazole Impurity 50 Hydrazine, [1-ethyl-2-(phenylmethoxy)propyl]-,[S-(R*,R*)]-(9CI) [(2S,3S)-2-(benzyloxy)pentan-3-yl]hydrazine 2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxaldehyde 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine 4-Chloro-benzenesulfonic acid 5-(2,4-difluoro-phenyl)-5-[1,2,4]triazol-1-ylMethyl-tetrahydro-furan-3-ylMethyl ester

  • CarbaMic acid, [4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-, phenyl ester (9CI)
  • Posaconazole Impurity 14
  • PHENYL {4-[4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL]PHENYL}CARBAMATE
  • [4-[4-(4-Hydroxyphenyl)-1-piperazinyl]phenyl]carbamic acid phenyl ester
  • Posaconazole Diastereoisomer 3 (S,R,R,R)
  • Phenyl (4-(4-(4-hydroxyphenyl)
  • phenyl N-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl]carbamate
  • 4-(4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL)PHENYL CARBAMATE
  • piperazin-1-yl)phenylcarbamate
  • Posaconazole Impurity 56
  • Posaconazole Hydroxy Carbamate Impurity
  • Carbamic acid, N-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-, phenyl ester
  • Posaconazole SM2
  • Phenyl {4-[4-(4-Hydroxyphenyl)Piperazin-1-Yl]Phenyl}Carbamat...
  • Intermediate of Posaconazole
  • Phenyl {4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl}carbamate
  • 184177-81-9