ChemicalBook > CAS DataBase List > (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester
(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester
- Product Name
- (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester
- CAS No.
- 149809-43-8
- Chemical Name
- (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester
- Synonyms
- (5R-cis)-Toluene-4-sulfonic acid;((3R,5R)-5-((1H-1,2,4-triazol-1-yl)Methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)Methyl 4-Methylbenzenesulfonate;2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[[(4-Methylphenyl)sulfonyl]oxy]Methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol;Posaconazole A;Posaconazole int1;((3S,5R)-5-((1H-1;US-DMF No.: 033193;Posaconazole inter-1;Posaconazole Main Ring;Posaconazole Impurity 53
- CBNumber
- CB22128616
- Molecular Formula
- C21H21F2N3O4S
- Formula Weight
- 449.47
- MOL File
- 149809-43-8.mol
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(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester Property
- Melting point:
- 100-102°C
- Boiling point:
- 608.1±65.0 °C(Predicted)
- Density
- 1.40
- storage temp.
- -20°C Freezer, Under Inert Atmosphere
- solubility
- slightly sol. in Chloroform
- form
- powder to crystal
- pka
- 2.75±0.10(Predicted)
- color
- White to Orange to Green
- InChIKey
- DFWVLCJRFGIRAK-HRAATJIYSA-N
- CAS DataBase Reference
- 149809-43-8(CAS DataBase Reference)
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Safety
- HS Code
- 2934.99.4400
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H311Toxic in contact with skin
H331Toxic if inhaled
H341Suspected of causing genetic defects
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P308+P313IF exposed or concerned: Get medical advice/attention.
P310Immediately call a POISON CENTER or doctor/physician.
P330Rinse mouth.
P361Remove/Take off immediately all contaminated clothing.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
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N-Bromosuccinimide Price
TCI Chemical
- Product number
- D4537
- Product name
- (3S,5R)-5-(2,4-Difluorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]oxolan-3-ylmethyl p-Toluenesulfonate
- Purity
- >98.0%(HPLC)
- Packaging
- 1g
- Price
- $457
- Updated
- 2021/12/16
TCI Chemical
- Product number
- D4537
- Product name
- (3S,5R)-5-(2,4-Difluorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]oxolan-3-ylmethyl p-Toluenesulfonate
- Purity
- >98.0%(HPLC)
- Packaging
- 200mg
- Price
- $123
- Updated
- 2024/03/01
TRC
- Product number
- T535900
- Product name
- (5R-cis)-Toluene-4-sulfonicAcid5-(2,4-Difluorophenyl)-5-[1,2,4]triazol-1-ylmethyltetrahydrofuran-3-ylmethylEster
- Packaging
- 100mg
- Price
- $790
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- HCH0029265
- Product name
- (5R-CIS)-TOLUENE-4-SULFONIC ACID 5-(2,4-DIFLUOROPHENYL)-5-(1H-1,2,4-TRIAZOL-1-YL)METHYLTETRAHYDROFURAN-3-YLMETHYL ESTER
- Purity
- 95.00%
- Packaging
- 100MG
- Price
- $1709.98
- Updated
- 2021/12/16
Ark Pharm
- Product number
- P000097815
- Product name
- ((3R,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl 4-methylbenzenesulfonate
- Purity
- 97%
- Packaging
- 5g
- Price
- $553
- Updated
- 2021/12/16
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(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester Chemical Properties,Usage,Production
Description
(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester is a pharmaceutical intermediate ingredient for Posaconazole is one of the newest triazole antifungal agents approved by the FDA for the prevention of invasive Aspergillus and Candida infections in immunocompromised patients. Such patients include haematopoietic stem cell transplant patients with graft-versus-host disease and patients with haematological malignancies undergoing chemotherapy.
Chemical Properties
White Crystalline Solid
Uses
Posaconazole intermediate. Antifungal agent.
(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester Suppliers
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View Lastest Price from (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester manufacturers
WUHAN FORTUNA CHEMICAL CO., LTD
- Product
- Posaconazole Intermediate 149809-43-8
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%min
- Supply Ability
- 500kgs
- Release date
- 2021-10-18
Shaanxi Dideu New Materials Co. Ltd
- Product
- (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester 149809-43-8
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 10000KGS
- Release date
- 2024-11-15
ShenZhen H&D Pharmaceutical Technology Co., LTD
- Product
- posaconazole impurity 13 149809-43-8
- Price
- US $0.00-0.00/mg
- Min. Order
- 10mg
- Purity
- 98%
- Supply Ability
- 500mg
- Release date
- 2024-06-28
149809-43-8, (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl esterRelated Search:
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1,2,4-Triazole
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2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one,
1H-Benzotriazole
Ribavirin
D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxyMethyl)-1-(1H-1,2,4-triazol-1-yl)-
Ascoric Acid
Posaconazole Impurity 44
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Posaconazole iMpurity 4
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PHENYL {4-[4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL]PHENYL}CARBAMATE
Posaconazole inter-8