ChemicalBook > CAS DataBase List > 8-Chloro-3-iodoimidazo[1,2-a]pyrazine

8-Chloro-3-iodoimidazo[1,2-a]pyrazine

Product Name
8-Chloro-3-iodoimidazo[1,2-a]pyrazine
CAS No.
1049677-32-8
Chemical Name
8-Chloro-3-iodoimidazo[1,2-a]pyrazine
Synonyms
8-Chloro-3-iodoimidazo[1,2-a]pyrazine;Imidazo[1,2-a]pyrazine, 8-chloro-3-iodo-
CBNumber
CB11482006
Molecular Formula
C6H3ClIN3
Formula Weight
279.47
MOL File
1049677-32-8.mol
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8-Chloro-3-iodoimidazo[1,2-a]pyrazine Property

Density 
2.34
storage temp. 
Storage temp. 2-8°C
Appearance
White to off-white Solid
InChI
InChI=1S/C6H3ClIN3/c7-5-6-10-3-4(8)11(6)2-1-9-5/h1-3H
InChIKey
RHQCTVNTDPLROD-UHFFFAOYSA-N
SMILES
C12=NC=C(I)N1C=CN=C2Cl
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Safety

HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Apolloscientific
Product number
OR321319
Product name
8-Chloro-3-iodoimidazo[1,2-a]pyrazine
Purity
97%
Packaging
250mg
Price
$56
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-M-0G
Product name
8-Chloro-3-iodoimidazo[1,2-a]pyrazine
Purity
97%
Packaging
250mg
Price
$157
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0043750
Product name
8-CHLORO-3-IODOIMIDAZO[1,2-A]PYRAZINE
Purity
95.00%
Packaging
0.25G
Price
$380
Updated
2021/12/16
Apolloscientific
Product number
OR321319
Product name
8-Chloro-3-iodoimidazo[1,2-a]pyrazine
Packaging
1g
Price
$445
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-M-0G
Product name
8-Chloro-3-iodoimidazo[1,2-a]pyrazine
Purity
97%
Packaging
1g
Price
$527
Updated
2021/12/16
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8-Chloro-3-iodoimidazo[1,2-a]pyrazine Chemical Properties,Usage,Production

Chemical Properties

off-white solid

Biological Activity

8-Chloro-3-iodoimidazo[1,2-a]pyrazine has demonstrated broad-spectrum antibacterial activity at low concentration levels against both gram-positive and gram-negative bacteria. Its antimicrobial potency can be increased by structural modifications.

Synthesis

8-chloroimidazo[1,2-a]pyrazine (5.2 g, 33.9 mmol) and N-iodo-succinimide (NIS) (8 g, 35.6 mmol) were combined with DMF (34 ml). The reaction mixture was stirred at RT for 48 h. After that, the water was added to the suspension, and the solid was filtered, washed with water and MeOH, and dried under HV to afford 8-Chloro-3-iodoimidazo[1,2-a]pyrazine (7.17 g, 25.6 mmol, 75.8% yield).

8-Chloro-3-iodoimidazo[1,2-a]pyrazine Preparation Products And Raw materials

Raw materials

Preparation Products

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8-Chloro-3-iodoimidazo[1,2-a]pyrazine Suppliers

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