(CYANOMETHYL)TRIPHENYLPHOSPHONIUM CHLORIDE
- Product Name
- (CYANOMETHYL)TRIPHENYLPHOSPHONIUM CHLORIDE
- CAS No.
- 4336-70-3
- Chemical Name
- (CYANOMETHYL)TRIPHENYLPHOSPHONIUM CHLORIDE
- Synonyms
- NSC 92174;Cyanomethyl triphenylphosph;cyanomethyl(triphenyl)phosphanium;(Cyanmethyl)triphenylphosphoniumchlorid;(cyanomethyl)triphenyl-phosphoniuchloride;Triphenyl(cyanomethyl)phosphonium·chloride;(CYANOMETHYL)TRIPHENYLPHOSPHONIUM CHLORIDE;Cyanomethyl triphenylphosphonium chloride,97%;2-(chlorotriphenyl-l5-phosphanyl)acetonitrile;(Cyanomethyl)triphenylphosphonium Chloride >
- CBNumber
- CB1148372
- Molecular Formula
- C20H17ClNP
- Formula Weight
- 337.78
- MOL File
- 4336-70-3.mol
(CYANOMETHYL)TRIPHENYLPHOSPHONIUM CHLORIDE Property
- Melting point:
- 268-270 °C
- storage temp.
- Inert atmosphere,Room Temperature
- form
- solid
- color
- White to Almost white
- Water Solubility
- very faint turbidity
- Sensitive
- Hygroscopic
- BRN
- 6222047
- InChIKey
- ARPLQAMUUDIHIT-UHFFFAOYSA-M
- CAS DataBase Reference
- 4336-70-3(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-20/21/22
- Safety Statements
- 37/39-26
- RIDADR
- 3276
- WGK Germany
- 3
- RTECS
- TA2075000
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29319090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H301Toxic if swalloed
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H331Toxic if inhaled
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 464937
- Product name
- (Cyanomethyl)triphenylphosphonium chloride
- Purity
- 98%
- Packaging
- 25g
- Price
- $106
- Updated
- 2025/07/31
- Product number
- C1739
- Product name
- (Cyanomethyl)triphenylphosphonium Chloride
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 25g
- Price
- $66
- Updated
- 2025/07/31
- Product number
- C1739
- Product name
- (Cyanomethyl)triphenylphosphonium Chloride
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 100g
- Price
- $198
- Updated
- 2025/07/31
- Product number
- C998525
- Product name
- (Cyanomethyl)triphenylphosphonium Chloride
- Packaging
- 500mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- C998525
- Product name
- (Cyanomethyl)triphenylphosphonium Chloride
- Packaging
- 2.5g
- Price
- $75
- Updated
- 2021/12/16
(CYANOMETHYL)TRIPHENYLPHOSPHONIUM CHLORIDE Chemical Properties,Usage,Production
Chemical Properties
off-white crystalline powder
Uses
Reactant involved in:
- Condenation reactions
- Wittig reactions
- Synthesis of phosphonium-iodonium ylides
- Preparation of α,β-unsaturated esters, amides, and nitriles
reaction suitability
reaction type: C-C Bond Formation
Synthesis
107-14-2
603-35-0
4336-70-3
The general procedure for the synthesis of cyanomethyltriphenylphosphonium chloride from chloroacetonitrile and triphenylphosphine was as follows: chloroacetonitrile (10 g, 0.132 mol) was added slowly and dropwise to a toluene solution (120 mL) of triphenylphosphine (23.5 g, 0.0895 mol), and the mixture was subsequently heated to reflux for 6 hours. After completion of the reaction, the reaction mixture was cooled to room temperature, the solid product was collected by filtration and washed with ether (2 x 20 mL). The final cyanomethyltriphenylphosphonium chloride (15 g, 49.58% yield) was obtained as a white solid. The product was characterized by NMR hydrogen spectroscopy (400 MHz, DMSO): δ 8.02-7.97 (m, 3H), 7.90-7.79 (m, 12H), 5.94 (s, 1H), 5.90 (s, 1H); Liquid Chromatography-Mass Spectrometry (electrospray ionization, m/z): [M + H]+ = 301.7.
References
[1] European Journal of Medicinal Chemistry, 2013, vol. 68, p. 132 - 138
[2] Chemistry - A European Journal, 2013, vol. 19, # 7, p. 2442 - 2449
[3] Journal of Organic Chemistry, 1980, vol. 45, # 26, p. 5316 - 5319
[4] International Journal of Chemical Kinetics, 2006, vol. 38, # 8, p. 496 - 502
[5] Patent: WO2016/105485, 2016, A2. Location in patent: Paragraph 0158
(CYANOMETHYL)TRIPHENYLPHOSPHONIUM CHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
(CYANOMETHYL)TRIPHENYLPHOSPHONIUM CHLORIDE Suppliers
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- sales@tcieurope.be
- Country
- Belgium
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- Advantage
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- Belgium
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View Lastest Price from (CYANOMETHYL)TRIPHENYLPHOSPHONIUM CHLORIDE manufacturers
- Product
- (CYANOMETHYL)TRIPHENYLPHOSPHONIUM CHLORIDE 4336-70-3
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-09-30
- Product
- (CYANOMETHYL)TRIPHENYLPHOSPHONIUM CHLORIDE 4336-70-3
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
- Product
- (CYANOMETHYL)TRIPHENYLPHOSPHONIUM CHLORIDE 4336-70-3
- Price
- US $20.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10000KG
- Release date
- 2020-11-10